Zobrazeno 1 - 10
of 452
pro vyhledávání: '"Marc K Rosenblum"'
Autor:
Matthias A. Karajannis, Bryan K. Li, Mark M. Souweidane, Benjamin Liechty, JinJuan Yao, Jamal K. Benhamida, Tejus A. Bale, Marc K. Rosenblum
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-4 (2022)
Abstract Biallelic inactivation of NF2 represents the primary or sole oncogenic driver event in the vast majority of schwannomas. We report on a four-year-old female who underwent subtotal resection of a right medullary intraparenchymal schwannoma. R
Externí odkaz:
https://doaj.org/article/b57182a0e66b4bef97901adae7315f1c
Autor:
Douglas A. Mata, Jamal K. Benhamida, Andrew L. Lin, Chad M. Vanderbilt, Soo-Ryum Yang, Liliana B. Villafania, Donna C. Ferguson, Philip Jonsson, Alexandra M. Miller, Viviane Tabar, Cameron W. Brennan, Nelson S. Moss, Martin Sill, Ryma Benayed, Ingo K. Mellinghoff, Marc K. Rosenblum, Maria E. Arcila, Marc Ladanyi, Tejus A. Bale
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, it
Externí odkaz:
https://doaj.org/article/e6a9da3b0b01489295be630dcbaceb95
Autor:
Matthew A Smith-Cohn, Zied Abdullaev, Kenneth D. Aldape, Martha Quezado, Marc K. Rosenblum, Chad M. Vanderbilt, Fausto J. Rodriguez, John Laterra, Charles G. Eberhart
Publikováno v:
Free Neuropathology, Vol 2 (2021)
The majority of astroblastoma occur in a cerebral location in children and young adults. Here we describe the unusual case of a 38-year-old man found to have a rapidly growing cystic enhancing circumscribed brainstem tumor with high grade histopathol
Externí odkaz:
https://doaj.org/article/a0c1d1e14a9a45e2b27ce51789faaf31
Autor:
Ingo K. Mellinghoff, Min Lu, Patrick Y. Wen, Jennie W. Taylor, Elizabeth A. Maher, Isabel Arrillaga-Romany, Katherine B. Peters, Benjamin M. Ellingson, Marc K. Rosenblum, Saewon Chun, Kha Le, Ania Tassinari, Sung Choe, Youssef Toubouti, Steven Schoenfeld, Shuchi S. Pandya, Islam Hassan, Lori Steelman, Jennifer L. Clarke, Timothy F. Cloughesy
Publikováno v:
Nature medicine, vol 29, iss 3
Vorasidenib and ivosidenib inhibit mutant forms of isocitrate dehydrogenase (mIDH) and have shown preliminary clinical activity against mIDH glioma. We evaluated both agents in a perioperative phase 1 trial to explore the mechanism of action in recur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9f679f7f754d03e40b27a62bb7565c
https://doi.org/10.1038/s41591-022-02141-2
https://doi.org/10.1038/s41591-022-02141-2
Autor:
Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adriana Heguy, Karina Ray, Arline Faustin, Olga Aminova, Igor Dolgalev, Stacie L. Stapleton, David Zagzag, Luis Chiriboga, Sharon L. Gardner, Jeffrey H. Wisoff, John G. Golfinos, David Capper, Volker Hovestadt, Marc K. Rosenblum, Dimitris G. Placantonakis, Sarah E. LeBoeuf, Thales Y. Papagiannakopoulos, Lukas Chavez, Sama Ahsan, Charles G. Eberhart, Stefan M. Pfister, David T. W. Jones, Matthias A. Karajannis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pineoblastoma is a highly aggressive and rare childhood brain cancer, and the genetic drivers of sporadic pineoblastoma are unknown. Here, the authors genomically interrogated pediatric and adult pineoblastomas and found novel variants including recu
Externí odkaz:
https://doaj.org/article/ead93584496f48eaacd71d7cac4d1501
Autor:
Benjamin Goode, Gourish Mondal, Michael Hyun, Diego Garrido Ruiz, Yu-Hsiu Lin, Jessica Van Ziffle, Nancy M. Joseph, Courtney Onodera, Eric Talevich, James P. Grenert, Iman H. Hewedi, Matija Snuderl, Daniel J. Brat, Bette K. Kleinschmidt-DeMasters, Fausto J. Rodriguez, David N. Louis, William H. Yong, M. Beatriz Lopes, Marc K. Rosenblum, Nicholas Butowski, Tarik Tihan, Andrew W. Bollen, Joanna J. Phillips, Arun P. Wiita, Iwei Yeh, Matthew P. Jacobson, Boris C. Bastian, Arie Perry, David A. Solomon
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Chordoid glioma is a rare low-grade brain tumor that originates from the anterior wall of the third ventricle where surgical resection is challenging; the clinical outcome of patients after subtotal resection or disease recurrence is poor. Here the a
Externí odkaz:
https://doaj.org/article/8ff58d0463294f3b9772e2541cb2ebc5
Autor:
Peter J. Cook, Rozario Thomas, Ram Kannan, Esther Sanchez de Leon, Alexander Drilon, Marc K. Rosenblum, Maurizio Scaltriti, Robert Benezra, Andrea Ventura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The use of mouse models has been an invaluable resource in cancer research but their generation is lengthy and costly. Here the authors describe an approach to generate engineered mouse models carrying specific gene fusions and, as a proof of princip
Externí odkaz:
https://doaj.org/article/ddd7582963914757848181c6d8b5e60f
Autor:
Lily A. McLaughlin, Onur Yildirim, Marc K. Rosenblum, Brandon S. Imber, Justin M. Haseltine, Michael J. Zelefsky, Heiko Schöder, Michael J. Morris, William M. Rafelson, Simone Krebs, Nelson S. Moss
Publikováno v:
Journal of Neuro-Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e16e6c3e2504faed2282b391c2b771d7
https://doi.org/10.1007/s11060-023-04355-x
https://doi.org/10.1007/s11060-023-04355-x
Autor:
Tom Rosenberg, Kee Kiat Yeo, Audrey Mauguen, Sanda Alexandrescu, Sanjay P Prabhu, Jessica W Tsai, Seth Malinowski, Mrinal Joshirao, Karishma Parikh, Sameer Farouk Sait, Marc K Rosenblum, Jamal K Benhamida, George Michaiel, Hung N Tran, Sonika Dahiya, Kara Kachurak, Gregory K Friedman, Julie I Krystal, Michael A Huang, Ashley S Margol, Karen D Wright, Dolly Aguilera, Tobey J MacDonald, Susan N Chi, Matthias A Karajannis
Publikováno v:
Neuro Oncol
Background The prognosis for patients with pediatric high-grade glioma (pHGG) is poor despite aggressive multimodal therapy. Objective responses to targeted therapy with BRAF inhibitors have been reported in some patients with recurrent BRAF-mutant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f4c96c60e61ce31e344d50486644e5
https://pubmed.ncbi.nlm.nih.gov/35750023
https://pubmed.ncbi.nlm.nih.gov/35750023
Autor:
Chris Jones, David T.W. Jones, Thomas S. Jacques, David W. Ellison, Sergey Popov, David Capper, Maria Vinci, Andrea Carai, Angela Mastronuzzi, Suzanne J. Baker, Felix Sahm, Stefan M. Pfister, Christof M. Kramm, Andreas von Deimling, Lynley V. Marshall, Fernando Carceller, Darren R. Hargrave, Kristian Aquilina, Matthias A. Karajannis, David S. Ziegler, Mark J. Cowley, Maria Tsoli, Stephen P. Lowis, Timothy E.G. Hassall, Andrew S. Moore, Simon Bailey, Francesca Diomedi-Camassei, Giovanna Stefania Colafati, Evelina Miele, Clare Mitchell, Tabitha Bloom, Olaf Witt, Marc Zuckermann, Dominik Sturm, Barbara C. Worst, Lotte Hiddingh, Andrey Korshunov, Pablo Hernáiz Driever, Felipe Andreiuolo, Torsten Pietsch, Simone Hettmer, Kornelius Kerl, Winand N.M. Dinjens, Martin Ebinger, Martin U. Schuhmann, Jens Schittenhelm, Michael Karremann, Michael Capra, Jane B. Cryan, Michael Farrell, Petter Brandal, Thale Kristin Olsen, David A. Solomon, Monika Ashok Davare, Lissa Baird, Matthew D. Wood, Barbara Faganel Kotnik, Mara Popović, Shani Caspi, Ho-Keung Ng, Roger Packer, Irene Slavc, Christine Haberler, Matthias Preusser, Tobey J. Macdonald, Paula Z. Proszek, Debbie Hughes, Marc K. Rosenblum, Stephen W. Gilheeney, Ira J. Dunkel, Martin Sill, Simon P. Robinson, Jessica K.R. Boult, Rachael Natrajan, Claire Cairns, Bassel Zebian, Christopher Chandler, Safa Al-Sarraj, Lawrence J. Doey, Andrew J. Martin, Leslie Bridges, Matija Snuderl, David E. Kram, Uwe Kordes, Ulrich Schüller, Jeffrey Knipstein, Stephen Crosier, Mellissa Maybury, Catherine Rowe, Kathreena M. Kurian, Michael Hubank, Ji Wen, Wilda Orisme, James D. Dalton, Kelly Haupfear, Mark Kristiansen, Jane Chalker, Aimee Avery, Amy R. Fairchild, Alex Virasami, Louise Howell, Anna Burford, Valeria Molinari, Diana M. Carvalho, Sara Temelso, Elisa Izquierdo, Iris Stoler, Tejus A. Bale, Scott Newman, Ruth G. Tatevossian, Jessica C. Pickles, Britta Ismer, Alan Mackay, Matthew Clarke
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04d97c92485c6eb10e27f5e8a1018f6
https://doi.org/10.1158/2159-8290.22535600
https://doi.org/10.1158/2159-8290.22535600
