Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Marc Jan van Goethem"'
Autor:
Haibin Qian, Ron A. Hoebe, Michel R. Faas, Marc Jan van Goethem, Emiel R. van der Graaf, Christoph Meyer, Harry Kiewiet, Sytze Brandenburg, Przemek M. Krawczyk
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cellular responses to DNA double-strand breaks (DSBs) not only promote genomic integrity in healthy tissues, but also largely determine the efficacy of many DNA-damaging cancer treatments, including X-ray and particle therapies. A growing bo
Externí odkaz:
https://doaj.org/article/f53b3751d3154ed185a148a298d26f11
Autor:
Nicholas T. Henthorn, Olga Sokol, Marco Durante, Ludovic De Marzi, Frederic Pouzoulet, Justyna Miszczyk, Pawel Olko, Sytze Brandenburg, Marc Jan van Goethem, Lara Barazzuol, Makbule Tambas, Johannes A. Langendijk, Marie Davídková, Vladimír Vondráĉek, Elisabeth Bodenstein, Joerg Pawelke, Antony J. Lomax, Damien C. Weber, Alexandru Dasu, Bo Stenerlöw, Per R. Poulsen, Brita S. Sørensen, Cai Grau, Mateusz K. Sitarz, Anne-Catherine Heuskin, Stephane Lucas, John W. Warmenhoven, Michael J. Merchant, Ran I. Mackay, Karen J. Kirkby
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Particle therapy is a growing cancer treatment modality worldwide. However, there still remains a number of unanswered questions considering differences in the biological response between particles and photons. These questions, and probing of biologi
Externí odkaz:
https://doaj.org/article/88275246ca1f4bacb94b8d81b66f3077
Autor:
Wilhelmina E. Radstake, Alessio Parisi, Silvana Miranda, Kiran Gautam, Randy Vermeesen, Emil Rehnberg, Kevin Tabury, Rob Coppes, Marc-Jan van Goethem, Sytze Brandenburg, Ulrich Weber, Claudia Fournier, Marco Durante, Bjorn Baselet, Sarah Baatout
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Without the protective shielding of Earth’s atmosphere, astronauts face higher doses of ionizing radiation in space, causing serious health concerns. Highly charged and high energy (HZE) particles are particularly effective in causing comp
Externí odkaz:
https://doaj.org/article/40a7222ff86546588c135ff1cd72113d
Autor:
Simon Sioen, Oniecha Vanhove, Barbara Vanderstraeten, Carlos De Wagter, Monique Engelbrecht, Charlot Vandevoorde, Evan De Kock, Marc-Jan Van Goethem, Anne Vral, Ans Baeyens
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Proton therapy is of great interest to pediatric cancer patients because of its optimal depth dose distribution. In view of healthy tissue damage and the increased risk of secondary cancers, we investigated DNA damage induction and repair of
Externí odkaz:
https://doaj.org/article/b5673780e80442879eb8c7d4baff6119
Autor:
Wilhelmina E. Radstake, Kiran Gautam, Silvana Miranda, Randy Vermeesen, Kevin Tabury, Emil Rehnberg, Jasmine Buset, Ann Janssen, Liselotte Leysen, Mieke Neefs, Mieke Verslegers, Jürgen Claesen, Marc-Jan van Goethem, Uli Weber, Claudia Fournier, Alessio Parisi, Sytze Brandenburg, Marco Durante, Bjorn Baselet, Sarah Baatout
Publikováno v:
Cells, Vol 12, Iss 2, p 246 (2023)
Human spaceflight is associated with several health-related issues as a result of long-term exposure to microgravity, ionizing radiation, and higher levels of psychological stress. Frequent reported skin problems in space include rashes, itches, and
Externí odkaz:
https://doaj.org/article/2c641cac29aa41b9ac46ac0c13434c34
Autor:
Marie Davídková, C Ankjærgaard, C.E. Andersen, A. Dasu, C. De Angelis, Ludovic De Marzi, Marijke De Saint-Hubert, Daniela Ekendahl, Nicholas Henthorn, Anna Jelínek Michaelidesová, Željka Knežević, Dawid Krzempek, Pawel Kukolowicz, Małgorzata Liszka, Stefano Lorentini, Amelia Maia Leite, Marija Majer, Matěj Navrátil, Brigitte Reniers, Wioletta Ślusarczyk-Kacprzyk, Marc Jan Van Goethem, Anne Vestergaard, Gloria Vilches-Freixas, Vladimír Vondráček, Michele Togno, Liliana Stolarczyk, Pawel Olko
Publikováno v:
Physica Medica. 104:S107-S108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fe51ad9e0250f7f344c2e6dfd364197
https://doi.org/10.1016/s1120-1797(22)02370-5
https://doi.org/10.1016/s1120-1797(22)02370-5
Autor:
Jana Kretschmer, Leonie Brodbek, Hui Khee Looe, Emiel van der Graaf, Marc Jan van Goethem, Harry Kiewiet, Francesco Olivari, Christoph Meyer, Björn Poppe, Sytze Brandenburg
Publikováno v:
Physics in Medicine and Biology, 67(14):145003. IOP PUBLISHING LTD
Objective. Point detector measurements in proton fields are perturbed by the volume effect originating from geometrical volume-averaging within the extended detector’s sensitive volume and density perturbations by non-water equivalent detector comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622c41081434e5b2657d98d43b674fc6
https://research.rug.nl/en/publications/5926ffcc-2a88-4d32-84e9-fbfe319eef08
https://research.rug.nl/en/publications/5926ffcc-2a88-4d32-84e9-fbfe319eef08
Autor:
Christoph F. J. Meyer, Haibin Qian, Harry Kiewiet, Sytze Brandenburg, Przemek M. Krawczyk, Emiel R van der Graaf, Marc-Jan van Goethem, Ron A. Hoebe, Michel R Faas
Publikováno v:
Scientific reports, 11(1):14528. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, 11(1):14528. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, 11(1):14528. Nature Publishing Group
Cellular responses to DNA double-strand breaks (DSBs) not only promote genomic integrity in healthy tissues, but also largely determine the efficacy of many DNA-damaging cancer treatments, including X-ray and particle therapies. A growing body of evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0619283b9251e6d645c91a284a7c8c89
https://doi.org/10.1038/s41598-021-92950-1
https://doi.org/10.1038/s41598-021-92950-1
Autor:
Antje Knopf, Marc-Jan van Goethem, Harry Kiewit, Johannes A. Langendijk, Sytze Brandenburg, Robert P. Coppes, Marco Kempers, Peter W. Nagle, Peter van Luijk
Publikováno v:
Radiotherapy and Oncology, 137, 125-129. ELSEVIER IRELAND LTD
To optimize beam delivery and conformality of proton therapy, MRI integration has been proposed. Therefore, we investigated if proton irradiation in a magnetic field would change biological responses. Our data in cancer cell lines and stem cell-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce54fbf73a29c8b0f7893fa0395ef65
https://research.rug.nl/en/publications/3a82ad77-cdf8-4cbe-b2b1-855d355d0cdb
https://research.rug.nl/en/publications/3a82ad77-cdf8-4cbe-b2b1-855d355d0cdb
Autor:
Mario Sacristan, Andrea Coronetti, Emil van der Graaf, Roberto Corsini, Antonio Gilardi, Miroslaw Marszalek, C. Frost, Carlo Cazzaniga, Athina Papadopoulou, Jialei Wang, Marc-Jan van Goethem, Wojtek Hajdas, Maris Tali, Anthony Dubois, Wilfrid Farabolini, Ruben Garcia Alia, Matteo Cecchetto, Arto Javanainen, Pablo Fernandez Martinez, Kacper Bilko, Laura Sinkunaite, Florent Castellani, Pedro Martin-Holgado, Jukka Jaatinen, Heikki Kettunen, Yolanda Morilla, Sytze Brandenburg, Giulia Bazzano, Mikko Rossi, Maria Kastriotou, Helmut Puchner, S. Fiore, Marie-Helene Moscatello, Manon Letiche, Harry Kiewiet
Publikováno v:
2020 IEEE Radiation Effects Data Workshop
2020 IEEE Radiation Effects Data Workshop, Dec 2020, Online, United States. ⟨10.1109/redw51883.2020.9325822⟩
2020 IEEE Radiation Effects Data Workshop (in conjunction with 2020 NSREC)
2020 IEEE Radiation Effects Data Workshop, REDW 2020-Held in conjunction with The IEEE Nuclear and Space Radiation Effects Conference
2020 IEEE Radiation Effects Data Workshop, Dec 2020, Online, United States. pp.1-8, ⟨10.1109/redw51883.2020.9325822⟩
2020 IEEE Radiation Effects Data Workshop, Dec 2020, Online, United States. ⟨10.1109/redw51883.2020.9325822⟩
2020 IEEE Radiation Effects Data Workshop (in conjunction with 2020 NSREC)
2020 IEEE Radiation Effects Data Workshop, REDW 2020-Held in conjunction with The IEEE Nuclear and Space Radiation Effects Conference
2020 IEEE Radiation Effects Data Workshop, Dec 2020, Online, United States. pp.1-8, ⟨10.1109/redw51883.2020.9325822⟩
International audience; The R2E project at CERN has tested a few commercial SRAMs and a custom-designed SRAM, whose data are complementary to various scientific publications. The experimental data include low- and high-energy protons, heavy ions, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8030bdc7e11f3b68e01d359a41beb72b
https://hal.archives-ouvertes.fr/hal-03346681
https://hal.archives-ouvertes.fr/hal-03346681