Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Marc J. Mentis"'
Autor:
Hassan Naqvi, Marc J. Mentis, Mark Gudesblatt, Luke Donatelli, Vijay Dhawan, David Eidelberg, Mark Forrest Gordon, Dominique Delalot, Christine Edwards
Publikováno v:
Movement Disorders. 21:549-555
Anticholinesterase (AChE) drugs are being prescribed off label for nonmotor symptoms in Parkinson's disease (PD). Theoretically, these drugs can impair motor function. A small literature suggests AChE therapy has little effect on clinical motor evalu
Autor:
Marc J. Mentis, David Eidelberg, Catherine Lozza, Maren Carbon, Jean-Claude Baron, R.M. Marié
Publikováno v:
Human Brain Mapping. 22:236-245
It is assumed widely that the clinical expression of Parkinson's Disease (PD), both motor and cognitive, is subtended by topographically distributed brain networks. However, little is known about the functional neuroanatomy of executive dysfunction i
Autor:
David Eidelberg, Christine Edwards, Dennis J. Zgaljardic, Andrew Feigin, Dominique Delalot, Vijay Dhawan, Marc J. Mentis
Publikováno v:
Hum Brain Mapp
Early‐stage nondemented Parkinson's disease (PD((es))) patients can learn short but not long sequences as well as controls. We have previously shown that to achieve normal performance, PD((es)) patients activated the same right‐sided cortical reg
Autor:
Andrew Feigin, T. Nakamura, C. Ghez, Vijay Dhawan, Maria Felice Ghilardi, C. Edwards, David Eidelberg, Marc J. Mentis
Publikováno v:
Neurology. 60:612-619
Background: Although the pathophysiology remains unknown, most nondemented patients with PD have difficulty with frontal tasks, including trial-and-error sequence learning. If given time, they can perform cognitive tasks of moderate difficulty as wel
Autor:
Christine Edwards, Yilong Ma, Maren Carbon, Marc J. Mentis, Deborah Raymond, Susan B. Bressman, David Eidelberg, James R. Moeller, Maja Trošt
Publikováno v:
Annals of Neurology. 52:853-856
The DYT1 dystonia mutation is associated with an abnormal metabolic brain network characterized by hypermetabolism of the basal ganglia, supplementary motor area, and the cerebellum. In this study, we quantified the activity of this network in carrie
Autor:
Masafumi Fukuda, Vijay Dhawan, David Eidelberg, Andrew Feigin, Claude Ghez, Marc J. Mentis, Yilong Ma, Maren Carbon, Maria Felice Ghilardi
Publikováno v:
Annals of Neurology. 52:144-152
We used 15 O-labeled water and positron emission tomography to assess the effect of deep brain stimulation of the internal globus pallidus on motor sequence learning in Parkinson's disease. Seven right-handed patients were scanned on and off stimulat
Autor:
Vijay Dhawan, Kenneth Perrine, David Eidelberg, Brian Berlin, Marc J. Mentis, Paul J. Mattis, Anthony R. McIntosh, Andy Feigin, Christine Edwards
Publikováno v:
American Journal of Psychiatry. 159:746-754
A multivariate analysis of baseline brain metabolism was used to investigate the relationships among pathophysiological mechanisms responsible for cognitive dysfunction and dysphoria in nondemented patients with Parkinson's disease.Using [(18)F]fluor
Autor:
Serge Przedborski, David Eidelberg, V. Jackson-Lewis, Andrew Feigin, James R. Moeller, Marc J. Mentis, Masafumi Fukuda, Vijay Dhawan
Publikováno v:
Neurology. 57:2083-2088
To assess the effects of levodopa on resting-state brain metabolism in PD.In previous studies the authors used [18F] fluorodeoxyglucose (FDG) and PET to quantify regional metabolic abnormalities in PD. They found that this disease is characterized re
Autor:
Barbara Levine, Stanley I. Rapoport, Sandeep Sobti, Trey Sunderland, Mark B. Schapiro, Jennifer Lai, Marc J. Mentis, Jack S. Krasuski, Catherine Connolly, Judy Friz
Publikováno v:
Neuropsychopharmacology. 25:555-564
Little is known about acetylcholine (ACh) modulation of central visual processing in humans. Receptor densities in visual brain regions are differentially distributed suggesting that receptor subtypes have different functions. Using PET, we have prev
Autor:
William C. Koller, Angelo Antonini, Andres M. Lozano, Claude Ghez, Maria Felice Ghilardi, Kelly E. Lyons, David Eidelberg, Masafumi Fukuda, Marc J. Mentis, John P. Hammerstad, Anthony E. Lang, Vijay Dhawan
Publikováno v:
Annals of Neurology. 49:155-164
We measured regional cerebral blood flow with H2 15O and positron emission tomography (PET) scanning at rest and during a motor task to study the mechanism of motor improvement induced by deep brain stimulation of the internal globus pallidus in Park