Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marc Hamma"'
Autor:
Maria Meier, Kristina Haub, Marie-Luise Schramm, Marc Hamma, Ulrike U. Bentele, Stephanie Dimitroff, Raphaela Gaertner, Bernadette Denk, Annika Benz, Eva Unternaehrer, Jens Pruessner
Publikováno v:
Psychoneuroendocrinology. 142
The Trier Social Stress Test (TSST) is a reliable and efficient protocol to induce acute psychosocial stress in the laboratory. If circumstances do not allow in-person assessments, an online version of the TSST (TSST-OL) could create more flexible re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a74371deb2af5cf2249888a2df2c2ac
https://pubmed.ncbi.nlm.nih.gov/35662007
https://pubmed.ncbi.nlm.nih.gov/35662007
Autor:
Tami Khazma, Atira Grossman, Julia Guez-Haddad, Chengye Feng, Hadas Dabas, Radhika Sain, Michal Weitman, Ran Zalk, Michail N. Isupov, Marc Hammarlund, Michael Hons, Yarden Opatowsky
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113026- (2023)
Summary: Wallerian axonal degeneration (WD) does not occur in the nematode C. elegans, in contrast to other model animals. However, WD depends on the NADase activity of SARM1, a protein that is also expressed in C. elegans (ceSARM/ceTIR-1). We hypoth
Externí odkaz:
https://doaj.org/article/7e3ef32d28c44b7ebf562503fb102f11
Publikováno v:
eLife, Vol 11 (2022)
Mitochondrial defects are tightly linked to axon degeneration, yet the underlying cellular mechanisms remain poorly understood. In Caenorhabditis elegans, PVQ axons that lack mitochondria degenerate spontaneously with age. Using an unbiased genetic s
Externí odkaz:
https://doaj.org/article/929d4f0e51b941cbbbb37a0d7d84bb1c
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009877 (2021)
Injured axons must regenerate to restore nervous system function, and regeneration is regulated in part by external factors from non-neuronal tissues. Many of these extrinsic factors act in the immediate cellular environment of the axon to promote or
Externí odkaz:
https://doaj.org/article/ccaffbe9ffaf44b0bdd1135d7788c8e6
Autor:
Lori Glenwinkel, Seth R Taylor, Kasper Langebeck-Jensen, Laura Pereira, Molly B Reilly, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Roger Pocock, Nenad Sestan, Marc Hammarlund, David M Miller III, Oliver Hobert
Publikováno v:
eLife, Vol 10 (2021)
The generation of the enormous diversity of neuronal cell types in a differentiating nervous system entails the activation of neuron type-specific gene batteries. To examine the regulatory logic that controls the expression of neuron type-specific ge
Externí odkaz:
https://doaj.org/article/af7e725ca0754a56a5647a1273beb41c
Autor:
Yuichi Sekine, Alexander Lin-Moore, Devon M. Chenette, Xingxing Wang, Zhaoxin Jiang, William B. Cafferty, Marc Hammarlund, Stephen M. Strittmatter
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 415-428 (2018)
Summary: Axonal regrowth is crucial for recovery from CNS injury but is severely restricted in adult mammals. We used a genome-wide loss-of-function screen for factors limiting axonal regeneration from cerebral cortical neurons in vitro. Knockdown of
Externí odkaz:
https://doaj.org/article/5c89e73ff23d433f812eaf32552d8352
Autor:
Chen Ding, Marc Hammarlund
Publikováno v:
eLife, Vol 7 (2018)
Functional axon regeneration requires regenerating neurons to restore appropriate synaptic connectivity and circuit function. To model this process, we developed an assay in Caenorhabditis elegans that links axon and synapse regeneration of a single
Externí odkaz:
https://doaj.org/article/f355df39517944bcae807e3550cd847d
Autor:
Tyson J. Edwards, Marc Hammarlund
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 272-283 (2014)
Growth cones facilitate the repair of nervous system damage by providing the driving force for axon regeneration. Using single-neuron laser axotomy and in vivo time-lapse imaging, we show that syndecan, a heparan sulfate (HS) proteoglycan, is require
Externí odkaz:
https://doaj.org/article/b4858e0e05dd4a4eb790f7b1bcf5d248
Autor:
Daniel C. Williams, Rachid El Bejjani, Paula Mugno Ramirez, Sean Coakley, Shin Ae Kim, Hyewon Lee, Quan Wen, Aravi Samuel, Hang Lu, Massimo A. Hilliard, Marc Hammarlund
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 553-563 (2013)
Inactivation of selected neurons in vivo can define their contribution to specific developmental outcomes, circuit functions, and behaviors. Here, we show that the optogenetic tool KillerRed selectively, rapidly, and permanently inactivates different
Externí odkaz:
https://doaj.org/article/f775bce7746240f584e4de4528b7ab6b
Autor:
Alexandra B Byrne, Rebecca D McWhirter, Yuichi Sekine, Stephen M Strittmatter, David M Miller III, Marc Hammarlund
Publikováno v:
eLife, Vol 5 (2016)
The ability of a neuron to regenerate its axon after injury depends in part on its intrinsic regenerative potential. Here, we identify novel intrinsic regulators of axon regeneration: poly(ADP-ribose) glycohodrolases (PARGs) and poly(ADP-ribose) poly
Externí odkaz:
https://doaj.org/article/b7f2b81c9905458f8d36ba102e5a8f23