Low prevalence of Merkel cell polyomavirus in human epithelial thymic tumors

Autor: Emil Chteinberg, Faisal Klufah, Dorit Rennspiess, Mick F. Mannheims, Myrurgia A. Abdul‐Hamid, Mario Losen, Marlies Keijzers, Marc H. De Baets, Anna Kordelia Kurz, Axel zur Hausen

Publikováno v: Thoracic Cancer, Vol 10, Iss 3, Pp 445-451 (2019)

Background The etiology of thymic epithelial tumors is unknown. Murine polyomavirus strain PTA has been shown to induce thymomas in mice. Recently, using diverse molecular techniques, we reported the presence of human polyomavirus 7 (HPyV7) in thymic

Externí odkaz: https://doaj.org/article/83b186621264433782b9b45f218acff2

Alpha7 acetylcholine receptor autoantibodies are rare in sera of patients diagnosed with schizophrenia or bipolar disorder.

Autor: Carolin Hoffmann, Jo Stevens, Shenghua Zong, Daan van Kruining, Abhishek Saxena, Cem İsmail Küçükali, Erdem Tüzün, Nazlı Yalçınkaya, Marc De Hert, Emiliano González-Vioque, Celso Arango, Jon Lindstrom, Marc H De Baets, Bart P F Rutten, Jim van Os, Peter Molenaar, Mario Losen, Pilar Martinez-Martinez

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0208412 (2018)

The α7 acetylcholine receptor (AChR) has been linked with the onset of psychotic symptoms and we hypothesized therefore that it might also be an autoimmune target. Here, we describe a new radioimmunoassay (RIA) using iodine 125-labelled α-bungaroto

Externí odkaz: https://doaj.org/article/fdadb8981e9a480eb87acf75812498f0

Globe Subluxation following Long-Term High-Dose Steroid Treatment for Myasthenia Gravis

Autor: Marc H. De Baets, Catherine Cassiman, Florit Marcuse, Jasmien Dam

Publikováno v: Case Reports in Ophthalmology
Case Reports in Ophthalmology, 11(3), 534-539. S. Karger AG
Case Reports in Ophthalmology, Vol 11, Iss 3, Pp 534-539 (2020)

This case report describes the unusual presentation of a globe subluxation following long-term high-dose oral steroid treatment for myasthenia gravis (MG). The patient presented initially with fluctuating vertical diplopia. Auto-antibodies against th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffaf4df2e34a25ad9234b0cdff3cfa6
https://doi.org/10.1159/000509527

DGAT1 overexpression in muscle by in vivo DNA electroporation increases intramyocellular lipid content

Autor: Berber D. Roorda, Matthijs K.C. Hesselink, Gert Schaart, Esther Moonen-Kornips, Pilar Martínez-Martínez, Mario Losen, Marc H. De Baets, Ronald P. Mensink, Patrick Schrauwen

Publikováno v: Journal of Lipid Research, Vol 46, Iss 2, Pp 230-236 (2005)

In adipose tissue, the microsomal enzyme 1,2-acyl CoA:diacylglyceroltransferase-1 (DGAT1) plays an important role in triglyceride storage. Because DGAT1 is expressed in skeletal muscle as well, we aimed to directly test the effect of DGAT1 on muscula

Externí odkaz: https://doaj.org/article/a7c1f97fe6a54164a78365d0156a7803

Methylome and transcriptome profiling in Myasthenia Gravis monozygotic twins

Autor: Marc H. De Baets, Sonia Berrih-Aknin, Laurent Servais, Frédérique Truffault, Nili Avidan, Bruno Eymard, Ariel Miller, Shimrat Mamrut, Mélinée Frenkian, Jiri Pitha, Elsebeth Staun-Ram, Tarek Sharshar

Publikováno v: Journal of Autoimmunity, 82, 62-73. Elsevier Science

Objective: To identify novel genetic and epigenetic factors associated with Myasthenia gravis (MG) using an identical twins experimental study design.Methods: The transcriptome and methylome of peripheral monocytes were compared between mono zygotic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea58756ea96530bb336a331a4f9c066a
https://ora.ox.ac.uk/objects/uuid:66d8358b-4df4-4093-8b5a-e7f074681ae4