Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Marc Gentzel"'
Autor:
Ihsan Dereli, Vladyslav Telychko, Frantzeskos Papanikos, Kavya Raveendran, Jiaqi Xu, Michiel Boekhout, Marcello Stanzione, Benjamin Neuditschko, Naga Sailaja Imjeti, Elizaveta Selezneva, Hasibe Tuncay, Sevgican Demir, Teresa Giannattasio, Marc Gentzel, Anastasiia Bondarieva, Michelle Stevense, Marco Barchi, Arp Schnittger, John R. Weir, Franz Herzog, Scott Keeney, Attila Tóth
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Programmed DNA double-strand break (DSB) formation is a crucial feature of meiosis in most organisms. DSBs initiate recombination-mediated linking of homologous chromosomes, which enables correct chromosome segregation in meiosis. DSBs are g
Externí odkaz:
https://doaj.org/article/c1a29489ee7845bb9dda93085bcd3d85
Autor:
Nikolai P. Jaschke, Sophie Pählig, Anupam Sinha, Timon E. Adolph, Maria Ledesma Colunga, Maura Hofmann, Andrew Wang, Sylvia Thiele, Julian Schwärzler, Alexander Kleymann, Marc Gentzel, Herbert Tilg, Ben Wielockx, Lorenz C. Hofbauer, Martina Rauner, Andy Göbel, Tilman D. Rachner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A combination of cell line, transgenic mouse and human genetic data implicates a proinflammatory function of Dickkopf1 across malignant and non-malignant cells.
Externí odkaz:
https://doaj.org/article/08ca554bb4284badb614763c54f2ed47
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Hexokinase 2 (Hxk2) of Saccharomyces cerevisiae is a dual function hexokinase, acting as a glycolytic enzyme and being involved in the transcriptional regulation of glucose-repressible genes. Relief from glucose repression is accompanied by
Externí odkaz:
https://doaj.org/article/265349834aac41c9bfc4f3b7a871f891
Autor:
Cristina Marisol Castillo Bautista, Kristin Eismann, Marc Gentzel, Silvia Pelucchi, Jerome Mertens, Hannah E. Walters, Maximina H. Yun, Jared Sterneckert
Publikováno v:
Cells, Vol 12, Iss 18, p 2247 (2023)
Aging is associated with the disruption of protein homeostasis and causally contributes to multiple diseases, including amyotrophic lateral sclerosis (ALS). One strategy for restoring protein homeostasis and protecting neurons against age-dependent d
Externí odkaz:
https://doaj.org/article/fa8aa0500c5d451eb80a3e477c6cd4bd
Autor:
Benjamin W. Dorschner, Ralf Wiedemuth, Ann-Christin Funke, Marc Gentzel, Mary-Louise Rogers, Sebastian Brenner, Sebastian Thieme
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inflammatory conditions are critically influenced by neuroimmune crosstalk. Cytokines and neurotrophic factors shape the responses of both nervous and immune systems. Although much progress has been made, most findings to date are based on expression
Externí odkaz:
https://doaj.org/article/8796deadeeed4a88995af1e0f1009f2d
Autor:
Maria Kotini, Elias H. Barriga, Jonathan Leslie, Marc Gentzel, Verena Rauschenberger, Alexandra Schambony, Roberto Mayor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Connexins are components of gap junctions that link cells and allow intercellular communication. Here, the authors show that the Connexin 43 carboxy tail interacts with basic transcription factor-3, leading to nuclear translocation and direct regulat
Externí odkaz:
https://doaj.org/article/b71dd62dbf3b48999beb230913ac1eec
Autor:
Janelle Lauer, Sandra Segeletz, Alice Cezanne, Giambattista Guaitoli, Francesco Raimondi, Marc Gentzel, Vikram Alva, Michael Habeck, Yannis Kalaidzidis, Marius Ueffing, Andrei N Lupas, Christian Johannes Gloeckner, Marino Zerial
Publikováno v:
eLife, Vol 8 (2019)
Intracellular trafficking depends on the function of Rab GTPases, whose activation is regulated by guanine exchange factors (GEFs). The Rab5 GEF, Rabex5, was previously proposed to be auto-inhibited by its C-terminus. Here, we studied full-length Rab
Externí odkaz:
https://doaj.org/article/59c0b315ce7c4837876fc46fb806c8fa
Autor:
Marc Gentzel, Alexandra Schambony
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Dishevelled (DVL) proteins are highly conserved in the animal kingdom and are important key players in β-Catenin-dependent and -independent Wnt signaling pathways. Vertebrate genomes typically comprise three DVL genes, DVL1, DVL2, and DVL3. Expressi
Externí odkaz:
https://doaj.org/article/daf27d095c094417ac37851dfecf06ce
Autor:
Maria Kotini, Elias H. Barriga, Jonathan Leslie, Marc Gentzel, Verena Rauschenberger, Alexandra Schambony, Roberto Mayor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Alexandra Schambony, which was incorrectly given as Alexandra Schambon. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/e299ae506e194567bff4ab92006cda0c
Autor:
Katharina Seitz, Verena Dürsch, Jakub Harnoš, Vitezslav Bryja, Marc Gentzel, Alexandra Schambony
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87132 (2014)
β-Catenin independent, non-canonical Wnt signaling pathways play a major role in the regulation of morphogenetic movements in vertebrates. The term non-canonical Wnt signaling comprises multiple, intracellularly divergent, Wnt-activated and β-Caten
Externí odkaz:
https://doaj.org/article/01757cc2e0e249979e3258fd9a6c6d28