Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Marc G, Ghany"'
Autor:
Maria Mironova, Marc G. Ghany
Publikováno v:
Vaccines, Vol 12, Iss 4, p 439 (2024)
Hepatitis B virus is a substantial contributor to cirrhosis and hepatocellular carcinoma (HCC) globally. Vaccination is the most effective method for prevention of hepatitis B and its associated morbidity and mortality, and the only method to prevent
Externí odkaz:
https://doaj.org/article/dcc7dd99d8bd4f3ab917db8d495f043a
Autor:
Akira Nishio, Sharika Hasan, Heiyoung Park, Nana Park, Jordan H. Salas, Eduardo Salinas, Lela Kardava, Paul Juneau, Nicole Frumento, Guido Massaccesi, Susan Moir, Justin R. Bailey, Arash Grakoui, Marc G. Ghany, Barbara Rehermann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Long-term dynamics of the humoral response to HCV in cured individuals aren’t well understood. Here, Nishio et al. show that virus-neutralizing antibody levels decrease in potency and breadth after cure of chronic hepatitis C, while HCV-specific me
Externí odkaz:
https://doaj.org/article/2d4cf5245d9644afaee0f1a8317aa30a
Autor:
Naveen Gara, Michele M. Tana, Meera Kattapuram, Sungyoung Auh, Lauren Sullivan, Nancy Fryzek, Mary Walter, Regina Umarova, Xiongce Zhao, Gavin Cloherty, Edward Doo, Theo Heller, T. Jake Liang, Marc G. Ghany
Publikováno v:
Hepatology Communications, Vol 5, Iss 11, Pp 1888-1900 (2021)
Nucleoside analogue (NA) therapy for chronic hepatitis B (CHB) is associated with improved clinical outcomes, but usually requires long‐term use. Whether treatment can be safely withdrawn and the factors associated with post‐withdrawal outcome ar
Externí odkaz:
https://doaj.org/article/1aa19527091a4b5298d59a09cd9fcedb
Autor:
Marc G. Ghany, Anna S. Lok
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
Chronic hepatitis B virus (HBV) infection remains a major global health problem. Hepatitis B surface antigen (HBsAg) loss has been accepted as the definition of a functional HBV cure. Recent studies found that while covalently closed circular DNA (cc
Externí odkaz:
https://doaj.org/article/4058523340964607bc259cc0176a7968
Autor:
Anna S. Lok, Fabien Zoulim, Geoffrey Dusheiko, Henry L.Y. Chan, Maria Buti, Marc G. Ghany, Anuj Gaggar, Jenny C. Yang, George Wu, John F. Flaherty, G. Mani Subramanian, Stephen Locarnini, Patrick Marcellin
Publikováno v:
Hepatology Communications, Vol 4, Iss 1, Pp 8-20 (2020)
In patients with chronic hepatitis B (CHB), loss of hepatitis B surface antigen (HBsAg) is considered a functional cure. However, HBsAg loss is uncommon with existing therapies, and predictive factors associated with HBsAg seroreversion are unknown.
Externí odkaz:
https://doaj.org/article/9554e258943144788e5c32360057cbb9
Autor:
Xiaoming Cheng, Marc G. Ghany
Publikováno v:
The Innovation, Vol 1, Iss 3, Pp 100067- (2020)
Externí odkaz:
https://doaj.org/article/79e9722fb7734633833299588e6652cd
Autor:
Qisheng Li, Brianna Lowey, Catherine Sodroski, Siddharth Krishnamurthy, Hawwa Alao, Helen Cha, Stephan Chiu, Ramy El-Diwany, Marc G. Ghany, T. Jake Liang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Using genome-wide miRNA mimic and hairpin inhibitor screens, Li et al. identify 31 miRNAs that either inhibit or promote hepatitis C virus (HCV) replication at different steps of the viral life cycle. Furthermore, human liver biopsies show that HCV d
Externí odkaz:
https://doaj.org/article/b0c163d7965544e795988bdc3ca37c83
Autor:
Niharika Samala, Richard Y. Wang, Sungyoung Auh, Abdalla Kara Balla, Lara Dakhoul, Harvey J. Alter, Patrizia Farci, Marwan Ghabril, Michael R. Lucey, Amol S. Rangnekar, K. Rajender Reddy, Marc G. Ghany
Publikováno v:
Journal of Viral Hepatitis. 29:1134-1142
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide. An increased risk for HEV infection has been reported in organ-transplant recipients, mainly from Europe. Prospective data on HEV prevalence in the United States (U.
Autor:
Mauricio Lisker‐Melman, Abdus S. Wahed, Marc G. Ghany, Raymond T. Chung, Wendy C. King, David E. Kleiner, Atul K. Bhan, Mandana Khalili, Mamta K. Jain, Mark Sulkowski, David K. Wong, Gavin Cloherty, Richard K. Sterling
Publikováno v:
Hepatology. 77:594-605
Liver injury may persist in patients with HBV receiving antiviral therapy who have ongoing transcription and translation. We sought to assess ongoing HBV transcription by serum HBV RNA, translation by serum hepatitis B core related antigen (HBcrAg),
Autor:
Marc G. Ghany, Wendy C. King, Amanda S. Hinerman, Anna SF. Lok, Mauricio Lisker-Melman, Raymond T. Chung, Norah Terrault, Harry L.A. Janssen, Mandana Khalili, William M. Lee, Daryl T.Y. Lau, Gavin A. Cloherty, Richard K. Sterling
Publikováno v:
Hepatology.