Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Marc Folcher"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Improving a drug delivery system is critical to treat central nervous system disorders. Here we studied an innovative approach based on implantation of a wireless-powered cell-based device in mice. This device, coupling biologic material and electron
Externí odkaz:
https://doaj.org/article/3e87c195de154062aad2fb38c0931bc6
Autor:
Katarina Cisarova, Marc Folcher, Ikram El Zaoui, Rosanna Pescini-Gobert, Virginie G Peter, Beryl Royer-Bertrand, Leonidas Zografos, Ann Schalenbourg, Michael Nicolas, Donata Rimoldi, Serge Leyvraz, Nicolò Riggi, Alexandre P Moulin, Carlo Rivolta
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009201 (2020)
Conjunctival melanoma (CJM) is a rare but potentially lethal and highly-recurrent cancer of the eye. Similar to cutaneous melanoma (CM), it originates from melanocytes. Unlike CM, however, CJM is relatively poorly characterized from a genomic point o
Externí odkaz:
https://doaj.org/article/6d13f01c6aab43f98a7237adb4d4366b
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Synthetic biology offers the potential for the design and implementation of rationally designed, complex genetic programmes. Here the authors design a genetic network to trigger the differentiation of patient derived IPSCs into beta-like cells.
Externí odkaz:
https://doaj.org/article/066ccf7797a74348a01c165392480612
Publikováno v:
mBio, Vol 2, Iss 1 (2011)
ABSTRACT Proteins that metabolize or bind the nucleotide second messenger cyclic diguanylate regulate a wide variety of important processes in bacteria. These processes include motility, biofilm formation, cell division, differentiation, and virulenc
Externí odkaz:
https://doaj.org/article/3a94640dd5384d75802f1f3aaf0db383
Autor:
Mukhtar Ullah, Atta Ur Rehman, Marc Folcher, Adnan Ullah, Faisal Usman, Abdur Rashid, Bilal Khan, Mathieu Quinodoz, Muhammad Ansar, Carlo Rivolta
Publikováno v:
Ophthalmic Research.
Introduction: Retinitis pigmentosa (RP) is a rare degenerative retinal disease caused by mutations in approximately seventy genes. Currently, despite the availability of large-scale DNA sequencing technologies, ~30-40% of patients still cannot be dia
Autor:
Claudia Delgado Simao, Laurenske A. Visser, William K. Redekop, Carin A. Uyl-de Groot, Biotza Gutierrez Arechederra, Encarna Escudero, Marc Folcher
Publikováno v:
Pharmacoeconomics
PharmacoEconomics, 40(1), 91-108. Adis
PharmacoEconomics, 40(1), 91-108. Adis
Background: Current first-line disease-modifying therapies (DMT) for multiple sclerosis (MS) patients are injectable or oral treatments. The Optogenerapy consortium is developing a novel bioelectronic cell-based implant for controlled release of beta
Autor:
Emilie Audouard, Fanny Michel, Vanessa Pierroz, Taeuk Kim, Lisa Rousselot, Béatrix Gillet-Legrand, Gaëlle Dufayet-Chauffaut, Peter Buchmann, Michael Florea, Alexander Khel, Kamilya Altynbekova, Claudia Delgaldo, Encarna Escudero, Alejandra Ben Aissa Soler, Nathalie Cartier, Francoise Piguet, Marc Folcher
Publikováno v:
Journal of Controlled Release, 352
Wireless powered optogenetic cell-based implant provides a strategy to deliver subcutaneously therapeutic proteins. Immortalize Human Mesenchymal Stem Cells (hMSC-TERT) expressing the bacteriophytochrome diguanylate cyclase (DGCL) were validated for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb8996437a67bf49f36b16e44f05476
Autor:
Ji Hoon, Han, Gavin, Ryan, Alyson, Guy, Lu, Liu, Mathieu, Quinodoz, Ingrid, Helbling, Joey E, Lai-Cheong, Julian, Barwell, Marc, Folcher, John A, McGrath, Celia, Moss, Carlo, Rivolta
Publikováno v:
Human molecular genetics. 31(12)
In the framework of the UK 100 000 Genomes Project, we investigated the genetic origin of a previously undescribed recessive dermatological condition, which we named LIPHAK (LTV1-associated Inflammatory Poikiloderma with Hair abnormalities and Acral
Autor:
Rosanna Pescini-Gobert, Beryl Royer-Bertrand, Ikram El Zaoui, Leonidas Zografos, Serge Leyvraz, Nicolo Riggi, Carlo Rivolta, Alexandre Moulin, Marc Folcher, Michael Nicolas, Katarina Cisarova, Virginie G. Peter, Donata Rimoldi, Ann Schalenbourg
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009201 (2020)
PLoS Genetics
PLoS genetics, vol. 16, no. 12, pp. e1009201
PLoS Genetics
PLoS genetics, vol. 16, no. 12, pp. e1009201
Conjunctival melanoma (CJM) is a rare but potentially lethal and highly-recurrent cancer of the eye. Similar to cutaneous melanoma (CM), it originates from melanocytes. Unlike CM, however, CJM is relatively poorly characterized from a genomic point o
Autor:
Alexandra Schulz, Anja Puklowski, Hitto Kaufmann, Marc Folcher, Aizhan Tastanova, Anne B. Tolstrup, Martin Fussenegger
Publikováno v:
Journal of Biotechnology. 219:72-85
The production of therapeutic antibodies using mammalian cells remains a high-priority in the biopharmaceutical manufacturing industry. Bioengineers have targeted different cellular processes, including transcription, translation, secretion and post-