Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marc Feary"'
Publikováno v:
Biotechnology Progress.
There are an ever-increasing number of biopharmaceutical candidates in clinical trials fueling an urgent need to streamline the cell line development process. A critical part of the process is the methodology used to generate and screen candidate cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52f3b6e9283111601ab8fe6f280fb3a
https://doi.org/10.1002/btpr.3137
https://doi.org/10.1002/btpr.3137
Publikováno v:
Biotechnology Progress. 33:17-25
In Lonza Biologics' GS Gene Expression System™, recombinant protein-producing GS-CHOK1SV cell lines are generated by transfection with an expression vector encoding both GS and the protein product genes followed by selection in MSX and glutamine-fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b5a622a54301b8d134930d196b2784
https://doi.org/10.1002/btpr.2372
https://doi.org/10.1002/btpr.2372
Publikováno v:
Biotechnology progress. 33(1)
In Lonza Biologics' GS Gene Expression System™, recombinant protein-producing GS-CHOK1SV cell lines are generated by transfection with an expression vector encoding both GS and the protein product genes followed by selection in MSX and glutamine-fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1f89df298225f6d13744006770be4a7
https://pubmed.ncbi.nlm.nih.gov/27689785
https://pubmed.ncbi.nlm.nih.gov/27689785
Autor:
Robert A. Young, Marc Feary, Lin Zhang, Rosalyn J. Masterton, Emma J. Mead, C. Mark Smales, Olga Obrezanova
Publikováno v:
The Biochemical journal. 472(3)
Translation initiation is on the critical pathway for the production of monoclonal antibodies (mAbs) by mammalian cells. Formation of a closed loop structure comprised of mRNA, a number of eukaryotic initiation factors (eIFs) and ribosomal proteins h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2360ad4ed89a408a93521eb8146d7f85
https://pubmed.ncbi.nlm.nih.gov/26965386
https://pubmed.ncbi.nlm.nih.gov/26965386
Autor:
Andrew J. Racher, Elaine Martin, Christopher J. O’Malley, Gary Montague, Richard M. Alldread, Root Tracy S, Lang Dietmar, Jane F. Povey, Carol M. Trim, Marc Feary, Christopher Mark Smales
Publikováno v:
Journal of biotechnology. 184
Despite many advances in the generation of high producing recombinant mammalian cell lines over the last few decades, cell line selection and development is often slowed by the inability to predict a cell line's phenotypic characteristics (e.g. growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9639fa6925e8ae0717d5833c2c88617
https://pubmed.ncbi.nlm.nih.gov/24858576
https://pubmed.ncbi.nlm.nih.gov/24858576