Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marc F. Hoylaerts"'
Autor:
Benedetta Izzi, Simona Costanzo, Alessandro Gialluisi, Amalia De Curtis, Sara Magnacca, Teresa Panzera, Augusto Di Castelnuovo, Maria Benedetta Donati, Chiara Cerletti, Marc F. Hoylaerts, Giovanni de Gaetano, Licia Iacoviello, on behalf of the Moli-sani Study Investigators
Publikováno v:
Bleeding, Thrombosis and Vascular Biology, Vol 2, Iss 3 (2023)
Platelet distribution width (PDW), a marker of platelet size heterogeneity used as a readout of processes leading to platelet production and destruction, was recently reported to tag platelet activation variability. As platelets participate in the pa
Externí odkaz:
https://doaj.org/article/cae9e3f66aa84267bf9495e51f1c739f
Autor:
Alfonsina Tirozzi, Benedetta Izzi, Fabrizia Noro, Annalisa Marotta, Francesco Gianfagna, Marc F. Hoylaerts, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Alessandro Gialluisi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neurodegenerative disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) suffer from the lack of risk-predictive circulating biomarkers, and clinical diagnosis occurs only when symptoms are evident. Among potential biomarkers, pl
Externí odkaz:
https://doaj.org/article/e8d6bb99555e4dd1a895e713bb3ea9e0
Autor:
Abderrahim Nemmar, Marc F. Hoylaerts
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 744 (2022)
Inhalation of particulate matter in polluted air causes direct, size-restricted passage in the circulation and pronounced lung inflammation, provoking platelet activation and (non)-fatal cardiovascular complications. To determine potency and mechanis
Externí odkaz:
https://doaj.org/article/9455fd8dd9184d548cd94ed9a6c6ef44
Autor:
Benedetta Izzi, Alessandro Gialluisi, Francesco Gianfagna, Sabatino Orlandi, Amalia De Curtis, Sara Magnacca, Simona Costanzo, Augusto Di Castelnuovo, Maria Benedetta Donati, Giovanni de Gaetano, Marc F. Hoylaerts, Chiara Cerletti, Licia Iacoviello, on behalf of the Moli-family Study Investigators
Publikováno v:
Cells, Vol 10, Iss 10, p 2737 (2021)
Defined as an index of platelet size heterogeneity, the platelet distribution width (PDW) is still a poorly characterized marker of platelet function in (sub)clinical disease. We presently validated PDW as a marker of P-selectin dependent platelet ac
Externí odkaz:
https://doaj.org/article/884491ad29cb4fe3b34e50b3f207e497
Autor:
Wen-Yi Yang, Thibault Petit, Nicholas Cauwenberghs, Zhen-Yu Zhang, Chang-Sheng Sheng, Lutgarde Thijs, Erika Salvi, Benedetta Izzi, Christophe Vandenbriele, Fang-Fei Wei, Yu-Mei Gu, Lotte Jacobs, Lorena Citterio, Simona Delli Carpini, Cristina Barlassina, Daniele Cusi, Marc F. Hoylaerts, Peter Verhamme, Tatiana Kuznetsova, Jan A. Staessen
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Platelet Endothelial Aggregation Receptor 1 (PEAR1), a membrane protein highly expressed in platelets and endothelial cells, plays a role in platelet contact-induced activation, sustained platelet aggregation and endothelial funct
Externí odkaz:
https://doaj.org/article/ab52d5991c9e43b6b1bab704a9a736b0
Autor:
Benedetta Izzi, Alfonsina Tirozzi, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Marc F. Hoylaerts, Licia Iacoviello, Alessandro Gialluisi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8817 (2020)
Alongside their function in primary haemostasis and thrombo-inflammation, platelets are increasingly considered a bridge between mental, immunological and coagulation-related disorders. This review focuses on the link between platelets and the pathop
Externí odkaz:
https://doaj.org/article/f45316daafd748ceb7a9fe4ed79a32c1
Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1069 (2018)
Chromosomal interactions connect distant enhancers and promoters on the same chromosome, activating or repressing gene expression. PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and meg
Externí odkaz:
https://doaj.org/article/5918ebf1178549eb9f74460158e319e5
Publikováno v:
Journal of Obesity, Vol 2010 (2010)
Background. The pituitary adenylate cyclase activating polypeptide (PACAP) may affect adipogenesis and adipose tissue formation through interaction with its G-protein-coupled receptor VPAC1. Methods. We have used a monoclonal antibody (MAb 23A11) blo
Externí odkaz:
https://doaj.org/article/4d18603fd8a2407b89961e25bb10087a
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Autor:
Bartosz, Ditkowski, Tiago R, Veloso, Martyna, Bezulska-Ditkowska, Andreas, Lubig, Stefan, Jockenhoevel, Petra, Mela, Ramadan, Jashari, Marc, Gewillig, Bart, Meyns, Marc F, Hoylaerts, Ruth, Heying
Publikováno v:
Journal of visualized experiments : JoVE. (143)
Various valved conduits and stent-mounted valves are used for right ventricular outflow tract (RVOT) valve replacement in patients with congenital heart disease. When using prosthetic materials however, these grafts are susceptible to bacterial infec
Autor:
Caroline, Kardeby, Knut, Fälker, Elizabeth J, Haining, Maarten, Criel, Madelene, Lindkvist, Ruben, Barroso, Peter, Påhlsson, Liza U, Ljungberg, Mattias, Tengdelius, G Ed, Rainger, Stephanie, Watson, Johannes A, Eble, Marc F, Hoylaerts, Jonas, Emsley, Peter, Konradsson, Steve P, Watson, Yi, Sun, Magnus, Grenegård
Publikováno v:
Blood advances. 3(3)
Fucoidans are sulfated fucose-based polysaccharides that activate platelets and have pro- and anticoagulant effects; thus, they may have therapeutic value. In the present study, we show that 2 synthetic sulfated α-l-fucoside-pendant glycopolymers (w