Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Marc F Hansen"'
Autor:
Vanessa Scanlon, Do Yu Soung, Naga Suresh Adapala, Elise Morgan, Marc F Hansen, Hicham Drissi, Archana Sanjay
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138194 (2015)
Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis. We investigated the effects of disrupted Cbl-PI3K interaction on fracture he
Externí odkaz:
https://doaj.org/article/73f71ab2ae8e4d8dafaf09d2c2491d1c
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Chondroclasts and osteoclasts have been previously identified as the cells capable of resorbing mineralized cartilage and bone matrices, respectively. While both cell types appear morphologically similar, contain comparable ultrastructural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368f34fb031ee21244eab4ea6a63ec75
http://link.springer.com/article/10.1186/s13075-020-02259-z
http://link.springer.com/article/10.1186/s13075-020-02259-z
Autor:
Nickolas B. Reimer, Cynthia B. Alander, Marc F. Hansen, Abul Arif, Hicham Drissi, David K. Monson
Publikováno v:
Techniques in Orthopaedics. 34:275-286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd16f21a125582d9e7c6dee20f5a146
https://doi.org/10.1097/bto.0000000000000408
https://doi.org/10.1097/bto.0000000000000408
Publikováno v:
Journal of Cellular Physiology. 233:8666-8676
Osteoarthritis (OA) is a degenerative disease and a major cause of chronic disability in aging individuals. Cathepsin K (CatK), encoded by the Ctsk gene, has been implicated in the pathogenesis of pycnodysostosis and osteoporosis. The use of a select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de38a99938f524728c6fb36cfed6feb7
https://doi.org/10.1002/jcp.26745
https://doi.org/10.1002/jcp.26745
Autor:
De-Chen Lin, Marc F. Hansen, Masashi Sanada, Jian-Jun Xie, H. Phillip Koeffler, Motohiro Kato, Seishi Ogawa, Norihiko Kawamata, Tadayuki Akagi, Dhong Hyun Lee, Carl W. Miller, Jennifer D. Akunowicz
Publikováno v:
International Journal of Oncology. 50:863-872
Osteosarcoma (OS) has a high degree of chromosomal instability and total copy number (CN) changes. We examined 58 human OS samples including 40 primary tumors, 11 explants, and 7 cell lines using single nucleotide polymorphism (SNP) arrays, and revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af061e30dc3e83a49f4af57335fd536
https://doi.org/10.3892/ijo.2017.3864
https://doi.org/10.3892/ijo.2017.3864
Publikováno v:
Journal of Cellular Physiology. 230:2951-2960
Bone remodeling requires osteoclast activation, resorption, and reversal, prior to osteoblast migration into the bone pit. The Receptor Activator of NF-κB (RANK) signaling pathway plays an important role in bone remodeling. Two components of the RAN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03cf73bec25bc449ab5adb326bbed8d3
https://doi.org/10.1002/jcp.25024
https://doi.org/10.1002/jcp.25024
Autor:
Marc F. Hansen, Hicham Drissi, Jungeun Yu, Peter Maye, Bhavita Walia, Archana Sanjay, Vanessa Scanlon
Publikováno v:
Bone. 95
The periosteum contains multipotent skeletal progenitors that contribute to bone repair. The signaling pathways regulating the response of periosteal cells to fracture are largely unknown. Phosphatidylinositol-3 Kinase (PI3K), a prominent lipid kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a568fff8ec35ef288235ad1581871058
https://pubmed.ncbi.nlm.nih.gov/27884787
https://pubmed.ncbi.nlm.nih.gov/27884787
Autor:
Marc F. Hansen, Margaret Seton
Osteosarcoma arising in pagetic bone is rare, estimated to occur in less than 1% of persons with Paget’s disease of bone (PDB) and accounting for a small percentage of those osteosarcomas occurring in adults >40 years of age. Consistent with the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128f784bc718e8859a06740df8851613
https://doi.org/10.1016/b978-0-12-805083-5.00007-5
https://doi.org/10.1016/b978-0-12-805083-5.00007-5
Autor:
Omar M.E. Albagha, Jacques P. Brown, Julie C. Crockett, Tim Cundy, Deborah L. Galson, Marc F. Hansen, Miep H. Helfrich, Rob Layfield, Laëtitia Michou, Stuart H. Ralston, Sarah L. Rea, Sakamuri V. Reddy, Ian R. Reid, G. David Roodman, Margaret Seton, Quanhong Sun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54eb5dabe8da7ed43c05f857dcbaa8f3
https://doi.org/10.1016/b978-0-12-805083-5.00015-4
https://doi.org/10.1016/b978-0-12-805083-5.00015-4
Paget’s disease of bone (PDB) is associated with a germline mutation in Sequestosome1/p62 (SQSTM1) found in ≤16 % of sporadic cases worldwide, and in 19–46 % of those studied with familial PDB. The P392L is the most prevalent mutation identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835625cfacaf14876ec6371942eb6901
https://europepmc.org/articles/PMC4847721/
https://europepmc.org/articles/PMC4847721/