Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marc Espina"'
The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice
Autor:
Marc Espina, Nadia Di Franco, Martina Brañas-Navarro, Irene Rodriguez Navarro, Veronica Brito, Laura Lopez-Molina, Carlos Costas-Insua, Manuel Guzmán, Silvia Ginés
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106225- (2023)
Increasing evidence indicates that a key factor in neurodegenerative diseases is the activation of the unfolded protein response (UPR) caused by an accumulation of misfolded proteins in the endoplasmic reticulum (ER stress). Particularly, in Huntingt
Externí odkaz:
https://doaj.org/article/ede8d1825f004ae789741daebb76f3ed
Autor:
Nadia Di Franco, Analia Bortolozzi, Leticia Campo, Marc Espina Cortes, Laura Lopez, Silvia Gines Padros
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1c9bb228dff19776d90e1b6a313604
https://doi.org/10.1136/jnnp-2022-ehdn.248
https://doi.org/10.1136/jnnp-2022-ehdn.248
Autor:
Marc Espina, Laura López-Molina, Anika Pupak, Nadia Di Franco, Verónica Brito, Juan Carlos Arévalo, Sílvia Ginés
Publikováno v:
A: Pathogenic mechanisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa9b7902c805b2f6f10b15e0d5c6261
https://doi.org/10.1136/jnnp-2022-ehdn.21
https://doi.org/10.1136/jnnp-2022-ehdn.21
Autor:
Anika Pupak, Ankita Singh, Anna Sancho-Balsells, Rafael Alcalá-Vida, Marc Espina, Albert Giralt, Eulàlia Martí, Ulf Andersson Vang Ørom, Silvia Ginés, Verónica Brito
Publikováno v:
Pupak, A, Singh, A, Sancho-Balsells, A, Alcalá-Vida, R, Espina, M, Giralt, A, Martí, E, Ørom, U A V, Ginés, S & Brito, V 2022, ' Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice ', Cellular and Molecular Life Sciences, vol. 79, no. 8, 416 . https://doi.org/10.1007/s00018-022-04444-6
N6-methyladenosine (m6A) regulates many aspects of RNA metabolism and is involved in learning and memory processes. Yet, the impact of a dysregulation of post-transcriptional m6A editing on synaptic impairments in neurodegenerative disorders remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487f7e90ea2c9b3a88ce0ade9ba0ae94
https://doi.org/10.1007/s00018-022-04444-6
https://doi.org/10.1007/s00018-022-04444-6
Autor:
David Martín-Gutiérrez, Ignacio Rodríguez-Crespo, Giovanni Marsicano, Joaquin Botta, Leyre Urigüen, José Sánchez-Prieto, Marc Espina, Rebeca Diez-Alarcia, Irene B. Maroto, Carlos Costas-Insua, Nuria García-Font, Raquel Bajo-Grañeras, Peter J. McCormick, Roser Cortés, Vicent Casadó, Andrea Ruiz-Calvo, Manuel Guzmán, Enric I. Canela, M. Teresa Vilaró, Ismael Galve-Roperh, Estefanía Moreno, Silvia Ginés, Guadalupe Mengod, Luigi Bellocchio, Ricardo Martín
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (38), pp.7924-7941. ⟨10.1523/JNEUROSCI.0821-21.2021⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (38), pp.7924-7941. ⟨10.1523/JNEUROSCI.0821-21.2021⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CB1R). Accruing evidence supports that cannabinoid action relies on context-dependent factors, such as the biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37fb9bb32a834bae66d420b7820be79
http://hdl.handle.net/2445/181159
http://hdl.handle.net/2445/181159
Autor:
Carlos, Costas-Insua, Estefanía, Moreno, Irene B, Maroto, Andrea, Ruiz-Calvo, Raquel, Bajo-Grañeras, David, Martín-Gutiérrez, Rebeca, Diez-Alarcia, M Teresa, Vilaró, Roser, Cortés, Nuria, García-Font, Ricardo, Martín, Marc, Espina, Joaquín, Botta, Silvia, Ginés, Peter J, McCormick, José, Sánchez-Prieto, Ismael, Galve-Roperh, Guadalupe, Mengod, Leyre, Urigüen, Giovanni, Marsicano, Luigi, Bellocchio, Enric I, Canela, Vicent, Casadó, Ignacio, Rodríguez-Crespo, Manuel, Guzmán
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(38)
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd8879eb8ef3feca3fd27f37eb6c62be
https://pubmed.ncbi.nlm.nih.gov/34353897
https://pubmed.ncbi.nlm.nih.gov/34353897
Autor:
Albert Giralt, Jordi Alberch, Mercè Masana, Verónica Brito, Anna Castañé, Esther Sieiro, Aida Royes, Silvia Ginés, Marc Espina, Jean-Antoine Girault
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
[Background] Depression is the most common psychiatric condition in Huntington’s disease (HD), with rates more than twice those found in the general population. At the present time, there is no established molecular evidence to use as a basis for d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43c0f9481e8454177081b7c883edc8f
http://hdl.handle.net/2445/183694
http://hdl.handle.net/2445/183694