Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Marc Erhardt"'
FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria
Autor:
Manuel Halte, Ekaterina P. Andrianova, Christian Goosmann, Fabienne F. V. Chevance, Kelly T. Hughes, Igor B. Zhulin, Marc Erhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The bacterial flagellum, which facilitates motility, is composed of ~20 structural proteins organized into a long extracellular filament connected to a cytoplasmic rotor-stator complex via a periplasmic rod. Flagellum assembly is regulated b
Externí odkaz:
https://doaj.org/article/1fae30fb18c340a380f649d28be01a86
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract Standardized and thoroughly characterized genetic tools are a prerequisite for studying cellular processes to ensure the reusability and consistency of experimental results. The discovery of fluorescent proteins (FPs) represents a milestone
Externí odkaz:
https://doaj.org/article/80ebdd4bb1d9418093f032e9dc8df56d
Autor:
Vanessa Muñoz-Gutierrez, Fabián A. Cornejo, Katja Schmidt, Christian K. Frese, Manuel Halte, Marc Erhardt, Alexander K. W. Elsholz, Kürşad Turgay, Emmanuelle Charpentier
Publikováno v:
mSystems, Vol 9, Iss 4 (2024)
ABSTRACTInitiation of bacterial DNA replication takes place at the origin of replication (oriC), a region characterized by the presence of multiple DnaA boxes that serve as the binding sites for the master initiator protein DnaA. This process is tigh
Externí odkaz:
https://doaj.org/article/c289fa04900e4f13b86da90c843c68c5
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The Gram-negative bacteria Salmonella enterica and Escherichia coli are important model organisms, powerful prokaryotic expression platforms for biotechnological applications, and pathogenic strains constitute major public health threats. To
Externí odkaz:
https://doaj.org/article/b60852bea5854f32a7e705e857316662
Autor:
Haidai Hu, Philipp F. Popp, Mònica Santiveri, Aritz Roa-Eguiara, Yumeng Yan, Freddie J. O. Martin, Zheyi Liu, Navish Wadhwa, Yong Wang, Marc Erhardt, Nicholas M. I. Taylor
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Bacteria swim using a flagellar motor that is powered by stator units. Vibrio spp. are highly motile bacteria responsible for various human diseases, the polar flagella of which are exclusively driven by sodium-dependent stator units (PomAB)
Externí odkaz:
https://doaj.org/article/48215e2da8dc4d61b27c6ba1f5880dbd
Autor:
Doaa Osama Saleh, Julia A Horstmann, María Giralt-Zúñiga, Willi Weber, Eugen Kaganovitch, Abilash Chakravarthy Durairaj, Enrico Klotzsch, Till Strowig, Marc Erhardt
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011451 (2023)
Both the bacterial flagellum and the evolutionary related injectisome encoded on the Salmonella pathogenicity island 1 (SPI-1) play crucial roles during the infection cycle of Salmonella species. The interplay of both is highlighted by the complex cr
Externí odkaz:
https://doaj.org/article/6c7ed7b28af540bdb2861dca71297c01
Autor:
Svenja Hüsing, Manuel Halte, Ulf van Look, Alina Guse, Eric J. C. Gálvez, Emmanuelle Charpentier, David F. Blair, Marc Erhardt, Thibaud T. Renault
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Type-III secretion systems (T3SSs) are capable of translocating proteins with high speed while maintaining the membrane barrier for small molecules. Here, a structure-function analysis of the T3SS pore complex elucidates the precise mechanisms enabli
Externí odkaz:
https://doaj.org/article/b4b81677e4d248c0b18979bbe7b55964
Autor:
Julia A. Horstmann, Michele Lunelli, Hélène Cazzola, Johannes Heidemann, Caroline Kühne, Pascal Steffen, Sandra Szefs, Claire Rossi, Ravi K. Lokareddy, Chu Wang, Laurine Lemaire, Kelly T. Hughes, Charlotte Uetrecht, Hartmut Schlüter, Guntram A. Grassl, Theresia E. B. Stradal, Yannick Rossez, Michael Kolbe, Marc Erhardt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.
Externí odkaz:
https://doaj.org/article/a2e29bfad3e243b1b5b15ef5ca3af75a
Autor:
Hélène Cazzola, Laurine Lemaire, Sébastien Acket, Elise Prost, Luminita Duma, Marc Erhardt, Petra Čechová, Patrick Trouillas, Fady Mohareb, Claire Rossi, Yannick Rossez
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a major cause of foodborne gastrointestinal illness. The adhesion of EHEC to host tissues is the first step enabling bacterial colonization. Adhesins such as fimbriae and flagella mediate
Externí odkaz:
https://doaj.org/article/aacf7a96bbcc4d109dd691887f0f6cbb
Autor:
Guillaume Paradis, Fabienne F. V. Chevance, Willisa Liou, Thibaud T. Renault, Kelly T. Hughes, Simon Rainville, Marc Erhardt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Many bacteria swim through liquids or crawl on surfaces by rotating long appendages called flagella. Flagellar filaments are assembled from thousands of subunits that are exported through a narrow secretion channel and polymerize beneath a c
Externí odkaz:
https://doaj.org/article/9d48816ce76f42f4a0ce35b547ad1dd8