Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Marc Ekker"'
Autor:
Wael M. Y. Mohamed, Marc Ekker
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/7aaef7d33bd74baab78a4e331860ce29
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1347 (2023)
The dlx genes encode transcription factors that establish a proximal–distal polarity within neural crest cells to bestow a regional identity during craniofacial development. The expression regions of dlx paralogs are overlapping yet distinct within
Externí odkaz:
https://doaj.org/article/eb3837f29d974eccb81b21fd157943c1
Autor:
Sandesh Panthi, Marc Ekker
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1253 (2023)
The Special Issue “Animal Models of Neurological Disorders: Where Are We Now [...]
Externí odkaz:
https://doaj.org/article/5f91f554c45f4884af4a08acd05b34b1
Autor:
Sara El-Sahli, Khang Hua, Andrew Sulaiman, Jason Chambers, Li Li, Eliya Farah, Sarah McGarry, Dan Liu, Peiyong Zheng, Seung-Hwan Lee, Jiefeng Cui, Marc Ekker, Marceline Côté, Tommy Alain, Xuguang Li, Vanessa M. D’Costa, Lisheng Wang, Suresh Gadde
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, accounting for the majority of breast cancer-related death. Due to the lack of specific therapeutic targets, chemotherapeutic agents (e.g., paclitaxel) rem
Externí odkaz:
https://doaj.org/article/01bd15f375e049938f736c0619b78c47
Autor:
Siavash Fazel Darbandi, Crystal Esau, Cindy Lesage-Pelletier, Simon Monis, Luc Poitras, Man Yu, Sofia Perin, Gary Hatch, Marc Ekker
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The Dlx homeodomain transcription factors play important roles in the differentiation and migration of GABAergic interneuron precursors. The mouse and human genomes each have six Dlx genes organized into three convergently transcribed bigene clusters
Externí odkaz:
https://doaj.org/article/2be369d121e64325b73da7065218567a
Autor:
Michael Kalyn, Marc Ekker
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Mitochondria are dynamic organelles that mediate the energetic supply to cells and mitigate oxidative stress through the intricate balance of fission and fusion. Mitochondrial dysfunction is a prominent feature within Parkinson disease (PD) etiologie
Externí odkaz:
https://doaj.org/article/e39359b839094fa28aca33ee36e14097
Autor:
Marc Ekker
Publikováno v:
eLife, Vol 10 (2021)
Zebrafish larvae models can be used to study the link between seizures and the neurodegeneration that follows brain trauma.
Externí odkaz:
https://doaj.org/article/50481bf026354080a6e75a92beea5060
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0229549 (2020)
Dysfunctions in the GABAergic system lead to various pathological conditions and impaired inhibitory function is one of the causes behind neuropathies characterized by neuronal hyper excitability. The Dlx homeobox genes are involved in the developmen
Externí odkaz:
https://doaj.org/article/031a6a25583a484fa2f6cf182db89f22
Autor:
Marc Ekker
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1644 (2021)
The neurotransmitter dopamine (DA) is generally associated with Parkinson’s disease (PD) [...]
Externí odkaz:
https://doaj.org/article/bac5ec82be324d70a40129859e5e9183
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214063 (2019)
Neural tube defects (NTDs), one of the most common birth defects in human, present a multifactorial etiology with a poorly defined genetic component. The Dlx5 and Dlx6 bigenic cluster encodes two evolutionary conserved homeodomain transcription facto
Externí odkaz:
https://doaj.org/article/75463ac422c9467fa3250fc4b139a57a