Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Marc E. Surette"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/acf0173d4b3d4c20b255e2d52d908fca
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2383-2396 (2018)
PUFAs are important constituents of membrane glycerophospholipids. However, changes in the capacities to incorporate and metabolize PUFAs when cells enter the cell cycle have not been thoroughly studied. In this study, differences in the incorporatio
Externí odkaz:
https://doaj.org/article/8bc63ffc4c9a4921b1e258e066b61580
Autor:
Maroua Mbarik, Samuel J. Poirier, Jérémie Doiron, Ayyoub Selka, David A. Barnett, Marc Cormier, Mohamed Touaibia, Marc E. Surette
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 5, Pp n/a-n/a (2019)
Abstract 5‐lipoxygenase (5‐LO) catalyzes the biosynthesis of leukotrienes, potent lipid mediators involved in inflammatory diseases, and both 5‐LO and the leukotrienes are validated therapeutic targets. Caffeic acid phenethyl ester (CAPE) is an
Externí odkaz:
https://doaj.org/article/72ce7de32be44923b0b2609d31f187f5
Autor:
Philippe Pierre Robichaud, Samuel J. Poirier, Luc H. Boudreau, Jérémie A. Doiron, David A. Barnett, Eric Boilard, Marc E. Surette
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 10, Pp 1821-1830 (2016)
Alkyne and azide analogs of natural compounds that can be coupled to sensitive tags by click chemistry are powerful tools to study biological processes. Arachidonic acid (AA) is a FA precursor to biologically active compounds. 19-Alkyne-AA (AA-alk) i
Externí odkaz:
https://doaj.org/article/96f465ded1894cbf96aeac01ccc35d14
Autor:
Audrey Isabel Chiasson, Samuel Robichaud, Fanta J. Ndongou Moutombi, Mathieu P. A. Hébert, Maroua Mbarik, Marc E. Surette, Mohamed Touaibia
Publikováno v:
Molecules, Vol 25, Iss 20, p 4686 (2020)
A novel series of zileuton-hydroxycinnamic acid hybrids were synthesized and screened as 5-lipoxygenase (5-LO) inhibitors in stimulated HEK293 cells and polymorphonuclear leukocytes (PMNL). Zileuton’s (1) benzo[b]thiophene and hydroxyurea subunits
Externí odkaz:
https://doaj.org/article/a97523b9f7f04864b0267c9d81daee1c
Autor:
Mariama Sambou, Jacques Jean-François, Fanta J. Ndongou Moutombi, Jérémie A. Doiron, Mathieu P.A. Hébert, Andrew P. Joy, Ngoc-Nu Mai-Thi, David A. Barnett, Marc E. Surette, Luc H. Boudreau, Mohamed Touaibia
Publikováno v:
Molecules, Vol 25, Iss 10, p 2397 (2020)
Soxhlet (SE), microwave-assisted (MAE) and ultrasound-assisted (UAE) extraction were compared using ten extraction solvents for their efficiency to extract phenolic and flavonoid antioxidants from Eastern Canada propolis. Extracts were compared for t
Externí odkaz:
https://doaj.org/article/9b11f523997f4b50a231f04a57a84c20
Autor:
Pierre-Philipe Roy, Diene Faye, Sébastien Blanchard, Marc Cormier, Jérémie A. Doiron, Marc E. Surette, Mohamed Touaibia
Publikováno v:
Journal of Chemistry, Vol 2017 (2017)
Leukotrienes are biosynthesized by the conversion of arachidonic acid by 5-Lipoxygenase and play a key role in many inflammatory disorders. Inspired by caffeic acid phenylethyl ester (CAPE) (2) and an analog carrying a triazole substituted by cinnamo
Externí odkaz:
https://doaj.org/article/220cbd36893348cb89aa3efa95892acf
Autor:
Luc H. Boudreau, Grégoire Lassalle-Claux, Marc Cormier, Sébastien Blanchard, Marco S. Doucet, Marc E. Surette, Mohamed Touaibia
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Leukotrienes are inflammatory mediators that actively participate in the inflammatory response and host defense against pathogens. However, leukotrienes also participate in chronic inflammatory diseases. 5-lipoxygenase is a key enzyme in the biosynth
Externí odkaz:
https://doaj.org/article/547be332a20f4d32bbb7e377daf63e50
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2665-2677 (2013)
Changes in fatty acid (FA) and glycerophospholipid (GPL) metabolism associated with cell cycle entry are not fully understood. In this study FA-GPL remodeling was investigated in resting and proliferating primary human T cells. Significant changes we
Externí odkaz:
https://doaj.org/article/f82bc457d0684255bbbd0797bad8a185
Autor:
Mohamed Touaibia, Marc E. Surette, Martin J. G. Hébert, Aurélie F. Paré, Jacques Jean-François, Luc M. LeBlanc
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14637-14650 (2012)
Caffeic acid phenethyl ester (CAPE) is a bioactive component isolated from propolis. A series of CAPE analogues was synthesized and their antiradical/antioxidant effects analyzed. The effect of the presence of the double bond and of the conjugated sy
Externí odkaz:
https://doaj.org/article/5731113d7e50474e8ef07dd8a00b3a4d