Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marc E. Bouillon"'
Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica
Autor:
Anand Chakroborty, Deiniol R. Pritchard, Marc E. Bouillon, Anna Cervi, Rolf Kraehenbuehl, Charlotte Wild, Caroline Fenn, Peter Holdsworth, Colin Capner, Gilda Padalino, Josephine E. Forde-Thomas, Joseph Payne, Brendan G. Smith, Maggie Fisher, Martina Lahmann, Mark S. Baird, Karl F. Hoffmann
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1869 (2023)
Infection with Fasciola hepatica (liver fluke) causes fasciolosis (or fascioliasis) and poses a considerable economic as well as welfare burden to both the agricultural and animal health sectors. Here, we explore the ex vivo anthelmintic potential of
Externí odkaz:
https://doaj.org/article/6e8ca26b7c334320af200daf96523567
Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica
Autor:
Hoffmann, Anand Chakroborty, Deiniol R. Pritchard, Marc E. Bouillon, Anna Cervi, Rolf Kraehenbuehl, Charlotte Wild, Caroline Fenn, Peter Holdsworth, Colin Capner, Gilda Padalino, Josephine E. Forde-Thomas, Joseph Payne, Brendan G. Smith, Maggie Fisher, Martina Lahmann, Mark S. Baird, Karl F.
Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1869
Infection with Fasciola hepatica (liver fluke) causes fasciolosis (or fascioliasis) and poses a considerable economic as well as welfare burden to both the agricultural and animal health sectors. Here, we explore the ex vivo anthelmintic potential of
Autor:
Eva Ramos-Morales, Gabriel de la Fuente, Robert J Nash, Radek Braganca, Stephane Duval, Marc E Bouillon, Martina Lahmann, C Jamie Newbold
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184517 (2017)
The antiprotozoal effect of saponins is transitory, as when saponins are deglycosylated to sapogenins by rumen microorganisms they become inactive. We hypothesised that the combination of saponins with glycosidase-inhibiting iminosugars might potenti
Externí odkaz:
https://doaj.org/article/039e41b0b8ac41a7ab1b2ea87e40d353
Autor:
Laura Bischoff, Michelle Buri, Elizabeth J. Wilkinson, Katia Bertocco, Marc E. Bouillon, Martina Lahmann, Lucy R. Davies
Publikováno v:
European Journal of Organic Chemistry. 2020:7470-7473
Autor:
Jack H Owen, Martina Lahmann, Carla C Briggs, Liam A Natrass, Rhodri Mir Williams, Paul W. Denny, Mark S. Baird, Angelos Loukaidis, Deiniol Pritchard, Charles F Cranston, Joseph Beckett, Elizabeth J. Wilkinson, Orlagh Anderson, Marc E. Bouillon
Publikováno v:
RSC Medicinal Chemistry
RSC medicinal chemistry, 2020, Vol.11(7), pp.833-842 [Peer Reviewed Journal]
RSC medicinal chemistry, 2020, Vol.11(7), pp.833-842 [Peer Reviewed Journal]
Hit anti-leishmanial saponin structures selected following primary and secondary screening.
Leishmaniasis is a neglected tropical disease caused by insect-vector borne protozoan parasites of the, Leishmania species. Whilst infection threatens an
Leishmaniasis is a neglected tropical disease caused by insect-vector borne protozoan parasites of the, Leishmania species. Whilst infection threatens an
Publikováno v:
Tetrahedron. 128:133104
Autor:
Anand Chakroborty, Deiniol Pritchard, Marc E. Bouillon, Anna Cervi, Alan Cookson, Charlotte Wild, Caroline Fenn, Joseph Payne, Peter Holdsworth, Colin Capner, Jenna O’Neill, Gilda Padalino, Josephine Forde-Thomas, Sandeep Gupta, Brendan G. Smith, Maggie Fisher, Martina Lahmann, Mark S. Baird, Karl F. Hoffmann
Publikováno v:
Veterinary Parasitology. 309:109766
Control of liver fluke infections remains a significant challenge in the livestock sector due to widespread distribution of drug resistant parasite populations. In particular, increasing prevalence and economic losses due to infection with Fasciola h
Publikováno v:
Carbohydrate Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e80229836008e49322eef1a1451a2a
https://doi.org/10.1201/9781351256087-9
https://doi.org/10.1201/9781351256087-9
Autor:
Marc E. Bouillon, Hartmut H. Meyer
Publikováno v:
Tetrahedron. 72:3151-3161
When treated with dilute inorganic acids N , N ′-diarylhydrazines (hydrazobenzenes) with an alkyl substituent in the 4-position undergo [5,5]-sigmatropic rearrangement reactions to furnish 4-(4′-aminophenyl)-4-alkylcyclohexa-2,5-dienimines ( ipso
Autor:
Stephen G. Pyne, Marc E. Bouillon
Publikováno v:
Tetrahedron Letters. 55:475-478
A diastereoselective concise synthesis of the iminosugars DMDP and DAB is presented starting from l -xylose and affording the two alkaloids in good yields of 35% and 22% over seven and eight steps, respectively. The Petasis borono–Mannich reaction