Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Marc E Surette"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0291399 (2024)
ObjectiveMouse models are valuable in preclinical studies of inflammatory arthritis. However, current methods for measuring disease severity or responses to treatment are not optimal. In this study a smart cage system using multiple sensors to measur
Externí odkaz:
https://doaj.org/article/a28bc5dc8d424b7fbfb7a76143768f54
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133168 (2015)
The objective of the current study was to determine whether prenatal iron deficiency induced during gestation in guinea pigs affected locomotor activity and learning and memory processes in the progeny. Dams were fed either iron-deficient anemic or i
Externí odkaz:
https://doaj.org/article/fd42ce41c87b46d99f0b86211fa5139a
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132607 (2015)
5-Lipoxygenase (5-LO) catalyzes leukotriene (LT) biosynthesis by a mechanism that involves interactions with 5-lipoxygenase activating protein (FLAP) and coactosin-like protein (CLP). 5-LO splice variants were recently identified in human myeloid and
Externí odkaz:
https://doaj.org/article/7424d3deb08e493989a1466428919201
Autor:
Luc H Boudreau, Jacques Maillet, Luc M LeBlanc, Jacques Jean-François, Mohamed Touaibia, Nicolas Flamand, Marc E Surette
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31833 (2012)
BACKGROUND: 5-lipoxygenase (5-LO) catalyses the transformation of arachidonic acid (AA) into leukotrienes (LTs), which are important lipid mediators of inflammation. LTs have been directly implicated in inflammatory diseases like asthma, atherosclero
Externí odkaz:
https://doaj.org/article/a23b61b93410451ab4b87a371ead0555
Autor:
Mohamed Touaibia, Diene Codou Faye, Jérémie A. Doiron, Audrey Isabel Chiasson, Sébastien Blanchard, Pierre-Philippe Roy, Marc E. Surette
Publikováno v:
Journal of Natural Products. 85:225-236
Sinapic acid is found in many edible plants and fruits, such as rapeseed, where it is the predominant phenolic compound. New sinapic acid phenethyl ester (SAPE) analogues were synthesized and screened as inhibitors of the biosynthesis of 5-lipoxygena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dca0efb9cc68eb2dcdb517eddb34fa9
https://doi.org/10.1021/acs.jnatprod.1c00982
https://doi.org/10.1021/acs.jnatprod.1c00982
Autor:
Mathieu P.A. Hébert, Ayyoub Selka, Andrea A. Lebel, Audrey Isabel Chiasson, Vanessa L. Gauvin, Alexis J. Matthew, Martin Hébert, Jérémie A. Doiron, Marco S. Doucet, Mohamed Touaibia, Marc E. Surette, Luc H. Boudreau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2a1689c537c8996596cc3f6c4f5d8f
https://doi.org/10.2139/ssrn.4352842
https://doi.org/10.2139/ssrn.4352842
Autor:
Jacob L Léger, Marie‐France N Soucy, Vanessa Veilleux, Robert D Foulem, Gilles A Robichaud, Marc E Surette, Eric P Allain, Luc H Boudreau
Publikováno v:
EMBO reports. 23
Inflammation is an essential process of host defense against infections, illness, or tissue damage. Polymorphonuclear neutrophils (PMN) are among the first immune cells involved in acute inflammatory responses and are on the front line in the fight a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5782fb1d0fdf32db7e185e554c67fef
https://doi.org/10.15252/embr.202254910
https://doi.org/10.15252/embr.202254910
Publikováno v:
Biochemical and biophysical research communications. 607
When performing western blots for protein detection using the classical Laemmli method, experimenters often encounter difficulties with the detection of transmembrane proteins involved in lipid or fatty acid metabolism. A crucial phase in sample prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24013de5b87aacc3f96294053d545e60
https://pubmed.ncbi.nlm.nih.gov/35367822
https://pubmed.ncbi.nlm.nih.gov/35367822
Publikováno v:
Insect Biochemistry and Molecular Biology. 152:103892
High-fat diets (HFDs) are often used to study metabolic disorders using different animal models. However, the underlying cellular mechanisms pertaining to the concurrent loss of metabolic homeostasis characteristics of these disorders are still uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b85ce0016ab4f22da1799770b5ee1ba
https://doi.org/10.1016/j.ibmb.2022.103892
https://doi.org/10.1016/j.ibmb.2022.103892
Autor:
Ayyoub Selka, Sandra Turcotte, Pierre J. Lyons, Alison Chiasson, Marc E. Surette, Mohamed Touaibia, Marc Cormier, Sonia Dastous, Jérémie A. Doiron
Publikováno v:
European Journal of Medicinal Chemistry. 179:347-357
The inhibition of 5-lipoxygenase (5-LO), the key enzyme for the biosynthesis of leukotrienes (LTs), has generated increasing enthusiasm as anti-inflammatory and antitumor strategies in recent years. Based on our previous studies, we synthesized a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e69fa57464ad9a3bc6960bd765a71a
https://doi.org/10.1016/j.ejmech.2019.06.060
https://doi.org/10.1016/j.ejmech.2019.06.060