Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marc E Seaman"'
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20807 (2011)
Quantification of microvascular network structure is important in a myriad of emerging research fields including microvessel remodeling in response to ischemia and drug therapy, tumor angiogenesis, and retinopathy. To mitigate analyst-specific variat
Externí odkaz:
https://doaj.org/article/9f4c82c65e154817ab68cac01c803a64
Autor:
Michael F. Gutknecht, Marc E. Seaman, Bo Ning, Daniel Auger Cornejo, Emily Mugler, Patrick F. Antkowiak, Christopher A. Moskaluk, Song Hu, Frederick H. Epstein, Kimberly A. Kelly
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Angiogenesis is essential for solid tumor progression. Here, the authors interrogate the proteome of pancreatic cancer endothelium via phage display and identify hornerin as a critical protein whose expression is essential to maintain the pancreatic
Externí odkaz:
https://doaj.org/article/968ae9dba40541f79ec82b4f597514db
Autor:
Bo Ning, Song Hu, Kimberly A. Kelly, Christopher A. Moskaluk, Frederick H. Epstein, Emily Mugler, Daniel Auger Cornejo, Michael F. Gutknecht, Patrick F. Antkowiak, Marc E. Seaman
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Sustained angiogenesis is essential for the development of solid tumors and metastatic disease. Disruption of signaling pathways that govern tumor vascularity provide a potential avenue to thwart cancer progression. Through phage display-based functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5516c3b4599362543b3df190f5f6b3ea
https://doaj.org/article/968ae9dba40541f79ec82b4f597514db
https://doaj.org/article/968ae9dba40541f79ec82b4f597514db
Autor:
Yaqin Xu, Brent A. French, Marc E. Seaman, Ronald J Beyers, Prasad Konkalmatt, Daniel M. O'Connor
Publikováno v:
Circulation: Cardiovascular Imaging. 6:478-486
Background— Cardiac magnetic resonance imaging has not been used previously to document the attenuation of left ventricular (LV) remodeling after systemic gene delivery. We hypothesized that targeted expression of extracellular superoxide dismutase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1f7e51686cba7737d44a2afc0e43ce
https://doi.org/10.1161/circimaging.112.000320
https://doi.org/10.1161/circimaging.112.000320
Autor:
Marc E. Seaman, Brent A. French, Kimberly A. Kelly, Michael F. Gutknecht, Siva Sai Krishna Dasa
Publikováno v:
Circulation. 130
Introduction: Pathological angiogenesis is a hallmark of cancer and other ischemic/inflammatory diseases including remodeling after myocardial infarction (MI) and diabetic retinopathy. Inhibitors of vascular endothelial growth factor (VEGF) signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cafd35a9aab155710ff95f7e93d5c2d
https://doi.org/10.1161/circ.130.suppl_2.15890
https://doi.org/10.1161/circ.130.suppl_2.15890
Autor:
Ohad Ilovich, Jacob Hesterman, Mihaela Plesescu, Vijay Gottumukkala, Paige Czarnecki, Daniel P. Bradley, Ildiko Polyak, Jack Hoppin, Kelly Davis Orcutt, Mohammed Q. Qutaish, Ozlem Yardibi, Marc E. Seaman
Publikováno v:
Cancer Research. 76:LB-185
Antibody-drug conjugates (ADCs) are optimized extensively in in vitro studies. Including drug-conjugate selection, linker stability and antibody affinity, most ADC characteristics have been studied to improve affinity, stability, efficacy and the bys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95605ec365237f5a0882d986e3b16992
https://doi.org/10.1158/1538-7445.am2016-lb-185
https://doi.org/10.1158/1538-7445.am2016-lb-185
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20807 (2011)
PLoS ONE
PLoS ONE
Quantification of microvascular network structure is important in a myriad of emerging research fields including microvessel remodeling in response to ischemia and drug therapy, tumor angiogenesis, and retinopathy. To mitigate analyst-specific variat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50499abbc25affa5913e79379db3849c
http://europepmc.org/articles/PMC3111429?pdf=render
http://europepmc.org/articles/PMC3111429?pdf=render
Autor:
Peter Waterman, Robert W. Ross, Ralph Weissleder, Lee Josephson, Marc E. Seaman, S. H. Chen, Kimberly A. Kelly, Brett Marinelli, Scott J. Rodig, Stephanie Thomas
Publikováno v:
Journal of Nanomedicine & Nanotechnology.
Prostate cancer is the most commonly diagnosed non-skin malignancy in the United States and presents with a wide range of aggressiveness from extremely slow-growing to highly aggressive. There is a clinical need to determine the metastatic potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52495b2b2f2b5faafec280b5198362e8
https://doi.org/10.4172/2157-7439.1000112
https://doi.org/10.4172/2157-7439.1000112
Imaging has become a crucial tool in oncology throughout the course of disease detection and management, and is an integral part of clinical trials. Anatomical and functional imaging led the way, providing valuable information used in the diagnosis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a826fcd7d7149f382120db4a29eaa6d
https://europepmc.org/articles/PMC3027202/
https://europepmc.org/articles/PMC3027202/
Autor:
Kimberly A. Kelly, Marc E. Seaman
Publikováno v:
Cancer Research. 73:3891-3891
Angiogenesis is vital to the growth, progression and ultimately metastasis of tumors. As such, many therapies have attempted to eradicate tumors through anti-angiogenic strategies. Most current and past preclinical and clinically approved therapies f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8184204bf00dc99ce047adbd13d7f06d
https://doi.org/10.1158/1538-7445.am2013-3891
https://doi.org/10.1158/1538-7445.am2013-3891