Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marc Dwenger"'
Autor:
Marc Dwenger, William J Kowalski, Fei Ye, Fangping Yuan, Joseph P Tinney, Shuji Setozaki, Takeichiro Nakane, Hidetoshi Masumoto, Peter Campbell, William Guido, Bradley B Keller
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
The immaturity of human induced pluripotent stem cell derived engineered cardiac tissues limits their ability to regenerate damaged myocardium and to serve as robust in vitro models for human disease and drug toxicity studies. Several chronic biomime
Externí odkaz:
https://doaj.org/article/c59b46060f414c0cb2eeff613521f0f7
Autor:
Riham Abouleisa, Jessica Miller, Ahmed Gebreil, Abou Bakr Salama, Marc Dwenger, Hania Abdelhafez, Reham Wahid, Adeniyi Adewumi, Mahmoud E. Soliman, Nader Abo-Dya, Tamer Mohamed
Background and Purpose: Myocardial infarction (MI) is the leading cause of mortality globally due in part to the limited ability of cardiomyocytes (CMs) to regenerate. Recently, we demonstrated that overexpression of 4 cell cycle factors, CDK1, CDK4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0cc963f4bf8e951d4cd3f738788ad8
https://doi.org/10.22541/au.167597489.96302144/v1
https://doi.org/10.22541/au.167597489.96302144/v1
Autor:
Thomas Pucci, Sean M. Raph, Gregory David Mack, Xuemei Hu, Matthew A. Nystoriak, Aruni Bhatnagar, Marc Dwenger, Joseph B. Moore, William M. Chilian, Vahagn Ohanyan
Publikováno v:
Circ Res
Rationale: Voltage-gated potassium (Kv) channels in vascular smooth muscle are essential for coupling myocardial blood flow (MBF) with the metabolic demand of the heart. These channels consist of a transmembrane pore domain that associates with auxil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957292fb13a0842094087f001827f227
https://pubmed.ncbi.nlm.nih.gov/33734818
https://pubmed.ncbi.nlm.nih.gov/33734818
Publikováno v:
Circulation. 142
Introduction: Myocardial perfusion is enhanced during periods of elevated cardiomyocyte oxygen consumption. The coupling between blood flow and myocardial oxygen demand is mediated by redox-dependent signals, yet the influence of cardiac workload on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::580b64d61602ccce8f1d68f5f9e424dc
https://doi.org/10.1161/circ.142.suppl_3.17038
https://doi.org/10.1161/circ.142.suppl_3.17038
Chronic Optogenetic Pacing of Human-Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues
Autor:
Marc, Dwenger, William J, Kowalski, Hidetoshi, Masumoto, Takeichiro, Nakane, Bradley B, Keller
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2191
The delivery of cells into damaged myocardium induces limited cardiac regeneration due to extensive cell death. In an effort to limit cell death, our lab formulates three-dimensional matrices as a delivery system for cell therapy. Our primary work ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d750ec7b2c5d64b5f4ec1df367e0abdb
https://pubmed.ncbi.nlm.nih.gov/32865744
https://pubmed.ncbi.nlm.nih.gov/32865744
Chronic Optogenetic Pacing of Human-Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues
Publikováno v:
Methods in Molecular Biology ISBN: 9781071608296
The delivery of cells into damaged myocardium induces limited cardiac regeneration due to extensive cell death. In an effort to limit cell death, our lab formulates three-dimensional matrices as a delivery system for cell therapy. Our primary work ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f262b46bc495ed6d0e310de14619cd24
https://doi.org/10.1007/978-1-0716-0830-2_10
https://doi.org/10.1007/978-1-0716-0830-2_10
Autor:
Shuji Setozaki, William J. Kowalski, Fei Ye, Fangping Yuan, Bradley B. Keller, Marc Dwenger, Hidetoshi Masumoto, Takeichiro Nakane, Joseph P. Tinney
Publikováno v:
Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension ISBN: 9789811511844
Despite improvements over the past 30 years, 10-year pediatric heart transplantation survival rates remain low and mechanical support is both expensive and relatively unavailable. In contrast to isolated cell therapies, implantable engineered cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1759b517440b35116f5306b054640a3f
https://doi.org/10.1007/978-981-15-1185-1_54
https://doi.org/10.1007/978-981-15-1185-1_54
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de73a83d5280d7e4a8747fe3d3b089a
https://doi.org/10.1096/fasebj.2020.34.s1.04524
https://doi.org/10.1096/fasebj.2020.34.s1.04524
Autor:
Takeichiro Nakane, Bradley B. Keller, Joseph P. Tinney, Fei Ye, Fangping Yuan, William J. Kowalski, Hidetoshi Masumoto, Marc Dwenger
Publikováno v:
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 23(4)
Biological tissues have complex, three-dimensional (3D) organizations of cells and matrix factors that provide the architecture necessary to meet morphogenic and functional demands. Disordered cell alignment is associated with congenital heart diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ec619f4a35cc7568556c9a9b781f14
https://pubmed.ncbi.nlm.nih.gov/28625174
https://pubmed.ncbi.nlm.nih.gov/28625174