Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Marc Dhenain"'
Autor:
Clément M. Garin, Marc Dhenain
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Non-human primates are a critical species for the identification of key biological mechanisms in normal and pathological aging. One of these primates, the mouse lemur, has been widely studied as a model of cerebral aging or Alzheimer's disea
Externí odkaz:
https://doaj.org/article/ab439a26ba48480cabb4b627536b804e
Autor:
Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Alzheimer’s disease (AD) is characterized by intracerebral deposition of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These peptides and proteins induce synaptic dysfunctions that are strongly correl
Externí odkaz:
https://doaj.org/article/8307e6636dd947a5bdd092741308d2d4
Autor:
Suzanne Lam, Anne-Sophie Hérard, Susana Boluda, Fanny Petit, Sabiha Eddarkaoui, Karine Cambon, The Brainbank Neuro-CEB Neuropathology Network, Jean-Luc Picq, Luc Buée, Charles Duyckaerts, Stéphane Haïk, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Alzheimer's disease (AD) is characterized by intracerebral accumulations of extracellular amyloid-β (Aβ) plaques and intracellular tau pathology that spread in the brain. Three types of tau lesions occur in the form of neuropil threads, ne
Externí odkaz:
https://doaj.org/article/7703dd8fe7624c2187d3305fec73d344
Autor:
Suzanne Lam, Fanny Petit, Anne-Sophie Hérard, Susana Boluda, Sabiha Eddarkaoui, Martine Guillermier, The Brain Bank Neuro-C. E. B. Neuropathology Network, Luc Buée, Charles Duyckaerts, Stéphane Haïk, Jean-Luc Picq, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-24 (2021)
Abstract Amyloid-β (Aβ) pathology transmission has been described in patients following iatrogenic exposure to compounds contaminated with Aβ proteins. It can induce cerebral Aβ angiopathy resulting in brain hemorrhages and devastating clinical i
Externí odkaz:
https://doaj.org/article/691891eba277482da3cf8c51aa1b5311
Publikováno v:
NeuroImage, Vol 251, Iss , Pp 118984- (2022)
Glutamate is the amino acid with the highest cerebral concentration. It plays a central role in brain metabolism. It is also the principal excitatory neurotransmitter in the brain and is involved in multiple cognitive functions. Alterations of the gl
Externí odkaz:
https://doaj.org/article/36a451df9ec141cfb565669d54d30395
Autor:
Anne-Sophie Hérard, Fanny Petit, Charlotte Gary, Martine Guillermier, Susana Boluda, Clément M. Garin, The Brainbank Neuro-CEB Neuropathology Network, Suzanne Lam, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract In humans, iatrogenic transmission of cerebral amyloid-β (Aβ)-amyloidosis is suspected following inoculation of pituitary-derived hormones or dural grafts presumably contaminated with Aβ proteins as well as after cerebral surgeries. Exper
Externí odkaz:
https://doaj.org/article/e5c5d8960af64e8e93784c6732f96349
Autor:
Ruth Aquino, Vidian de Concini, Marc Dhenain, Suzanne Lam, David Gosset, Laura Baquedano, Manuel G. Forero, Arnaud Menuet, Patrick Baril, Chantal Pichon
Publikováno v:
Cells, Vol 12, Iss 5, p 694 (2023)
Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers of Alzheimer’s disease (AD). Here, we investigated the panel of expressed blood miRNAs in response to aggregated Aβ1–42 peptides infused in the
Externí odkaz:
https://doaj.org/article/d952262f88954266850c0b091473b066
Autor:
Charlotte Gary, Suzanne Lam, Anne-Sophie Hérard, James E. Koch, Fanny Petit, Pauline Gipchtein, Stephen J. Sawiak, Raphaëlle Caillierez, Sabiha Eddarkaoui, Morvane Colin, Fabienne Aujard, Jean-Philippe Deslys, French Neuropathology Network, Emmanuel Brouillet, Luc Buée, Emmanuel E. Comoy, Fabien Pifferi, Jean-Luc Picq, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-21 (2019)
Abstract Alzheimer’s disease is characterized by cognitive alterations, cerebral atrophy and neuropathological lesions including neuronal loss, accumulation of misfolded and aggregated β-amyloid peptides (Aβ) and tau proteins. Iatrogenic inductio
Externí odkaz:
https://doaj.org/article/e39ef7713ddd47a9b3847bf54d779c5c
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 1178-1185 (2018)
We present a dataset made of 3D digital brain templates and of an atlas of the gray mouse lemur (Microcebus murinus), a small prosimian primate of growing interest for studies of primate biology and evolution. A template image was constructed from in
Externí odkaz:
https://doaj.org/article/4e7ef287a54d4d5eab033ee01b7f2a40
Autor:
Clément M. Garin, Nachiket A. Nadkarni, Brigitte Landeau, Gaël Chételat, Jean-Luc Picq, Salma Bougacha, Marc Dhenain
Publikováno v:
NeuroImage, Vol 226, Iss , Pp 117589- (2021)
Measures of resting-state functional connectivity allow the description of neuronal networks in humans and provide a window on brain function in normal and pathological conditions. Characterizing neuronal networks in animals is complementary to studi
Externí odkaz:
https://doaj.org/article/c609e703966b48199db3d3e76d6c7353