Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Marc Desforges"'
Autor:
Jérémie Prévost, Romain Gasser, Guillaume Beaudoin-Bussières, Jonathan Richard, Ralf Duerr, Annemarie Laumaea, Sai Priya Anand, Guillaume Goyette, Mehdi Benlarbi, Shilei Ding, Halima Medjahed, Antoine Lewin, Josée Perreault, Tony Tremblay, Gabrielle Gendron-Lepage, Nicolas Gauthier, Marc Carrier, Diane Marcoux, Alain Piché, Myriam Lavoie, Alexandre Benoit, Vilayvong Loungnarath, Gino Brochu, Elie Haddad, Hannah D. Stacey, Matthew S. Miller, Marc Desforges, Pierre J. Talbot, Graham T. Gould Maule, Marceline Côté, Christian Therrien, Bouchra Serhir, Renée Bazin, Michel Roger, Andrés Finzi
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100126- (2020)
Summary: SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. The Spike glycoproteins of SARS-CoV-2 mediate viral entry and are the main targets for
Externí odkaz:
https://doaj.org/article/f77f34cf5d734e3f9175ba9330620ffe
Autor:
Alan H. M. Wong, Aidan C. A. Tomlinson, Dongxia Zhou, Malathy Satkunarajah, Kevin Chen, Chetna Sharon, Marc Desforges, Pierre J. Talbot, James M. Rini
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Coronaviruses have a relatively high mutation rate, potentially allowing fast adaptation to changing pressures. Here, Wong et al. provide the structure of the receptor-binding domain (RBD) of the human coronavirus HCoV-229E and its receptor and analy
Externí odkaz:
https://doaj.org/article/f6588e45349a4419aa4c7ce1d24b3317
Publikováno v:
Pathogens, Vol 10, Iss 10, p 1267 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 231 million people globally, with more than 4.7 million deaths recorded by the World Health Organization as of 26 September 2021. In response to the pandemic, some co
Externí odkaz:
https://doaj.org/article/868b218423c14525a947499c05c75497
Autor:
Zhijie Li, Aidan CA Tomlinson, Alan HM Wong, Dongxia Zhou, Marc Desforges, Pierre J Talbot, Samir Benlekbir, John L Rubinstein, James M Rini
Publikováno v:
eLife, Vol 8 (2019)
The coronavirus S-protein mediates receptor binding and fusion of the viral and host cell membranes. In HCoV-229E, its receptor binding domain (RBD) shows extensive sequence variation but how S-protein function is maintained is not understood. Report
Externí odkaz:
https://doaj.org/article/eed3c0e9a1a2460c8ad3b9c833f16c92
Autor:
Alain Le Coupanec, Marc Desforges, Mathieu Meessen-Pinard, Mathieu Dubé, Robert Day, Nabil G Seidah, Pierre J Talbot
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005261 (2015)
Human coronaviruses (HCoV) are respiratory pathogens that may be associated with the development of neurological diseases, in view of their neuroinvasive and neurotropic properties. The viral spike (S) glycoprotein is a major virulence factor for sev
Externí odkaz:
https://doaj.org/article/208ee58fe19640f4ad635ae82303b18a
Autor:
Ana C. Blanchard, Marc Desforges, Annie-Claude Labbé, Cat Tuong Nguyen, Yves Petit, Dominic Besner, Kate Zinszer, Olivier Séguin, Zineb Laghdir, Kelsey Adams, Marie-Ève Benoit, Geneviève Leduc, Jean Longtin, Jiannis Ragoussis, David L. Buckeridge, Caroline Quach
Publikováno v:
CMAJ open. 10(4)
SARS-CoV-2 transmission has an impact on education. In this study, we assessed the performance of rapid antigen detection tests (RADTs) versus polymerase chain reaction (PCR) for the diagnosis of SARS-CoV-2 infection in school settings, and RADT use
Autor:
Stéphanie Beauchemin, Sarah Gobeille Paré, Julie Bestman-Smith, Christian Lavallée, Marc Desforges, Isabelle Goupil-Sormany, Florence Doualla-Bell, Lambert Busque, Mariève Jacob-Wagner, Hugues Charest, François Coutlée, Jeannot Dumaresq, Annie-Claude Labbé, Judith Fafard, Valérie Boucher, Guylaine Lépine, Manon St-Hilaire
Publikováno v:
Journal of Medical Virology
The objective of this study was to validate the use of spring water gargle (SWG) as an alternative to oral and nasopharyngeal swab (ONPS) for SARS‐CoV‐2 detection with a laboratory‐developed test. Healthcare workers and adults from the general
Publikováno v:
Virologie (Montrouge, France). 26(6)
Autor:
Pierre J, Talbot, Marc, Desforges
Publikováno v:
Virologie (Montrouge, France). 26(4)
For a large proportion of mankind, the word coronavirus only became a reality in the year 2020, as it was the cause of one of the worst pandemics of the last two centuries. Nevertheless, well before this ominous moment, human coronaviruses (HCoV) wer
Autor:
Geidy E Serrano, Jessica E Walker, Cécilia Tremblay, Ignazio S Piras, Matthew J Huentelman, Christine M Belden, Danielle Goldfarb, David Shprecher, Alireza Atri, Charles H Adler, Holly A Shill, Erika Driver-Dunckley, Shyamal H Mehta, Richard Caselli, Bryan K Woodruff, Chadwick F Haarer, Thomas Ruhlen, Maria Torres, Steve Nguyen, Dasan Schmitt, Steven Z Rapscak, Christian Bime, Joseph L Peters, Ellie Alevritis, Richard A Arce, Michael J Glass, Daisy Vargas, Lucia I Sue, Anthony J Intorcia, Courtney M Nelson, Javon Oliver, Aryck Russell, Katsuko E Suszczewicz, Claryssa I Borja, Madison P Cline, Spencer J Hemmingsen, Sanaria Qiji, Holly M Hobgood, Joseph P Mizgerd, Malaya K Sahoo, Haiyu Zhang, Daniel Solis, Thomas J Montine, Gerald J Berry, Eric M Reiman, Katharina Röltgen, Scott D Boyd, Benjamin A Pinsky, James L Zehnder, Pierre Talbot, Marc Desforges, Michael DeTure, Dennis W Dickson, Thomas G Beach
Publikováno v:
Journal of neuropathology and experimental neurology. 81(9)
Brains of 42 COVID-19 decedents and 107 non-COVID-19 controls were studied. RT-PCR screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene viral sequences in 7 regions (2.5% of 320 samples), concentrated in 4/20 subjects (20%). Add