Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marc Descatoire"'
Autor:
Eva-Maria Cox, Mohamed El-Behi, Stefanie Ries, Johannes F. Vogt, Vivien Kohlhaas, Thomas Michna, Benoît Manfroi, Mona Al-Maarri, Florian Wanke, Boaz Tirosh, Corinne Pondarre, Harry Lezeau, Nir Yogev, Romy Mittenzwei, Marc Descatoire, Sandra Weller, Jean-Claude Weill, Claude-Agnès Reynaud, Pierre Boudinot, Luc Jouneau, Stefan Tenzer, Ute Distler, Anne Rensing-Ehl, Christoph König, Julian Staniek, Marta Rizzi, Aude Magérus, Frederic Rieux-Laucat, F. Thomas Wunderlich, Nadine Hövelmeyer, Simon Fillatreau
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112378- (2023)
Summary: The signals controlling marginal zone (MZ) and follicular (FO) B cell development remain incompletely understood. Here, we show that AKT orchestrates MZ B cell formation in mice and humans. Genetic models that increase AKT signaling in B cel
Externí odkaz:
https://doaj.org/article/92cc14fd0e5540159395986a3869f5d7
Autor:
Marc Descatoire, Remi Fritzen, Samuel Rotman, Genevieve Kuntzelman, Xavier Charles Leber, Stephanie Droz-Georget, Adrian J. Thrasher, Elisabetta Traggiai, Fabio Candotti
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110474- (2022)
Summary: A main feature of Wiskott-Aldrich syndrome (WAS) is increased susceptibility to autoimmunity. A key contribution of B cells to development of these complications has been demonstrated through studies of samples from affected individuals and
Externí odkaz:
https://doaj.org/article/863a55212719468c9575a95c5d865b92
Autor:
Marc Descatoire, Benjamin P. Hurrell, Melissa Govender, Katiuska Passelli, Berenice Martinez-Salazar, Ramona Hurdayal, Frank Brombacher, Reto Guler, Fabienne Tacchini-Cottier
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Experimental infection with the protozoan parasite Leishmania major has been extensively used to understand the mechanisms involved in T helper cell differentiation. Following infection, C57BL/6 mice develop a small self-healing cutaneous lesion and
Externí odkaz:
https://doaj.org/article/de75154675af4b14ab424c3b2869d694
Autor:
Giuseppe Pantaleo, Pieter Leyssen, Kelvin Lau, Marc Descatoire, Didier Trono, Jérémy Campos, Victor S. Joo, Céline Pellaton, Yves Levy, Florence Pojer, Erica Lana, Alex Farina, Mathilde Foglierini, Caroline S. Foo, Rana Abdelnabi, Roger LeGrand, Laura Vangeel, Priscilla Turelli, Laurent Perez, Flurin Fiscalini, Line Esteves-Leuenberger, Berend Jan Bosch, Volker Thiel, Wenjuan Du, Geertruida M. Veldman, Alessandra Noto, Charlène Raclot, Johan Neyts, Davide Demurtas, Craig Fenwick
Publikováno v:
Cell Reports
Fenwick, Craig; Turelli, Priscilla; Perez, Laurent; Pellaton, Céline; Esteves-Leuenberger, Line; Farina, Alex; Campos, Jérémy; Lana, Erica; Fiscalini, Flurin; Raclot, Charlène; Pojer, Florence; Lau, Kelvin; Demurtas, Davide; Descatoire, Marc; Joo, Victor S; Foglierini, Mathilde; Noto, Alessandra; Abdelnabi, Rana; Foo, Caroline S; Vangeel, Laura; ... (2021). A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell reports, 37(2), p. 109814. Cell Press 10.1016/j.celrep.2021.109814
Cell Reports, 37(2). Elsevier Saunders
Cell reports, vol. 37, no. 2, pp. 109814
Fenwick, Craig; Turelli, Priscilla; Perez, Laurent; Pellaton, Céline; Esteves-Leuenberger, Line; Farina, Alex; Campos, Jérémy; Lana, Erica; Fiscalini, Flurin; Raclot, Charlène; Pojer, Florence; Lau, Kelvin; Demurtas, Davide; Descatoire, Marc; Joo, Victor S; Foglierini, Mathilde; Noto, Alessandra; Abdelnabi, Rana; Foo, Caroline S; Vangeel, Laura; ... (2021). A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell reports, 37(2), p. 109814. Cell Press 10.1016/j.celrep.2021.109814
Cell Reports, 37(2). Elsevier Saunders
Cell reports, vol. 37, no. 2, pp. 109814
Control of the ongoing SARS-CoV-2 pandemic is endangered by the emergence of viral variants with increased transmission efficiency, resistance to marketed therapeutic antibodies and reduced sensitivity to vaccine-induced immunity. Here, we screen B c
Autor:
Sandra K. Weller, Marc Descatoire
Publikováno v:
médecine/sciences. 31:647-653
In humans, CD27+ blood B cells with mutated immunoglobulin (Ig) receptors comprise two major populations: isotype-switched memory cells (IgG+ or IgA+CD27+) and IgM+IgD+CD27+ cells. While switched CD27+ cells are generated in germinal centers (GC) by
Autor:
Maya Chrabieh, Ying Wang, Sandra K. Weller, Elisabeth Israelsson, Katarzyna Bulek, Damien Chaussabel, Nicole Lemmens, Vincent Pedergnana, Laura Israel, Michael Levin, Jethro Herberg, Théo Lasseau, Carolina Prando, Andrew Moran, Vanessa Sancho-Shimizu, Zhao Zhang, François Vandenesch, Leonard E. Weisman, Jean-Laurent Casanova, Ling Yun, Erika Della Mina, Aziz Belkadi, Yuval Itan, Marc Descatoire, Lazaro Lorenzo, Willem J. B. van Wamel, Bruce Beutler, Avinash Abhyankar, Capucine Picard, Xiaoxia Li, Anne Puel, Peter D. Arkwright, Laurent Abel, Frédéric Batteux
Publikováno v:
Israel, L, Wang, Y, Bulek, K, Della Mina, E, Zhang, Z, Pedergnagna, V, Chrabieh, M, Lemmens, N A, Sancho-Shimizu, V, Descatoire, M, Lasseau, T, Israelsson, E, Lorenzo, L, Yun, L, Belkadi, A, Moran, A, Weisman, L E, Vandenesh, F, Batteux, F, Weller, S, Levin, M, Herberg, J, Abhyankar, A, Prando, C, Itan, Y, van Wamel, W, Picard, C, Abel, L, Chaussabel, D, Li, X, Beutler, B A, Arkwright, P, Casanova, J-L & Puel, A 2017, ' Human adaptive immunity rescues an inborn error of innate immunity ', Cell, vol. 168, no. 5, e10, pp. 789-800 . https://doi.org/10.1016/j.cell.2017.01.039
Cell
Cell, 2017, 168 (5), pp.789-800.e10. ⟨10.1016/j.cell.2017.01.039⟩
Cell, 168(5), 789-+. Cell Press
Cell
Cell, 2017, 168 (5), pp.789-800.e10. ⟨10.1016/j.cell.2017.01.039⟩
Cell, 168(5), 789-+. Cell Press
International audience; The molecular basis of the incomplete penetrance of monogenic disorders is unclear. We describe here eight related individuals with autosomal recessive TIRAP deficiency. Life-threatening staphylococcal disease occurred during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656382641bcd5014a6e378b5f88eeb47
https://www.research.manchester.ac.uk/portal/en/publications/human-adaptive-immunity-rescues-an-inborn-error-of-innate-immunity(2d563494-f9e8-42ae-9997-27fb4b87a393).html
https://www.research.manchester.ac.uk/portal/en/publications/human-adaptive-immunity-rescues-an-inborn-error-of-innate-immunity(2d563494-f9e8-42ae-9997-27fb4b87a393).html
Autor:
Claude-Agnès Reynaud, Sandra K. Weller, Jean-Claude Weill, Ismail Dogan, François Huetz, Marc Descatoire
Publikováno v:
Cellular and Molecular Life Sciences
Humoral memory is maintained by two types of persistent cells, memory B cells and plasma cells, which have different phenotypes and functions. Long-lived plasma cells can survive for a lifespan within a complex niche in the bone marrow and provide co
Autor:
Sandra, Weller, Marc, Descatoire
Publikováno v:
Medecine sciences : M/S. 31(6-7)
In humans, CD27+ blood B cells with mutated immunoglobulin (Ig) receptors comprise two major populations: isotype-switched memory cells (IgG+ or IgA+CD27+) and IgM+IgD+CD27+ cells. While switched CD27+ cells are generated in germinal centers (GC) by
Autor:
Emmanuel Jacquemin, Sabine Irtan, Christine Bole-Feysot, Jérôme Bouligand, Joseph Cohen, Nicolas Cagnard, Sandra K. Weller, Anne Guiochon-Mantel, A. Morali, Jean Feuillard, Sébastien Storck, Maria Iascone, Marc Descatoire, Claude-Agnès Reynaud, Sabine Sarnacki, Jean-Claude Weill
Publikováno v:
Journal of Experimental Medicine
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Identification in humans of a bona fide marginal zone B cell population, which differentiates from a splenic marginal zone precursor through a NOTCH2 signaling pathway.
Mouse splenic marginal zone precursors (MZPs) differentiate into marginal zo
Mouse splenic marginal zone precursors (MZPs) differentiate into marginal zo
Autor:
Mikael Ebbo, Marc Michel, Mehdi Khellaf, Nicolas Cagnard, Pauline Patin, Olivier Lambotte, Simon Le Gallou, David Boutboul, Marc Descatoire, Jean-Claude Weill, Christine Bole-Feysot, Olivier Fain, Mohamed Hamidou, François Huetz, Claude-Agnès Reynaud, Philippe Bierling, Matthieu Mahévas, Bertrand Godeau, Lionel Galicier
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2013, 123 (1), pp.432-42. 〈10.1172/JCI65689〉
Journal of Clinical Investigation, American Society for Clinical Investigation, 2013, 123 (1), pp.432-42. ⟨10.1172/JCI65689⟩
Journal of Clinical Investigation, 2013, 123 (1), pp.432-42. ⟨10.1172/JCI65689⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2013, 123 (1), pp.432-42. 〈10.1172/JCI65689〉
Journal of Clinical Investigation, American Society for Clinical Investigation, 2013, 123 (1), pp.432-42. ⟨10.1172/JCI65689⟩
Journal of Clinical Investigation, 2013, 123 (1), pp.432-42. ⟨10.1172/JCI65689⟩
International audience; Primary immune thrombocytopenia (ITP) is a disorder caused by autoantibody-mediated platelet destruction and decreased platelet production. Rituximab, a B cell-depleting agent, has become the first-line treatment for ITP; howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c2ebcb776ae962154cf4c0dce4bbe0
https://hal-pasteur.archives-ouvertes.fr/pasteur-00778075
https://hal-pasteur.archives-ouvertes.fr/pasteur-00778075