Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marc DeCristofaro"'
Autor:
Randall J. Bateman, David Kagan, Keith Mansfield, Neeta Shenoy, Julie Douville, Tim West, Geoffrey G. Goodrich, Randy L. Webb, Marc DeCristofaro, Chiara Buono, Wei Zhou, Frederic Cumin, Chandrassegar Saravanan, Mary S. Holubasch, Philip B. Verghese, Heidi A. Schoenfeld
Publikováno v:
Toxicology and Applied Pharmacology. 323:53-65
Sacubitril/valsartan (LCZ696) is the first angiotensin receptor neprilysin inhibitor approved to reduce cardiovascular mortality and hospitalization in patients with heart failure with reduced ejection fraction. As neprilysin (NEP) is one of several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b41e7e4be08e50b60a23d954de4a52
Autor:
Louise Pouliot, David A. Beckman, Marc DeCristofaro, Susan Y. Smith, Marilynn Schneider, Rana Samadfam
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 98:374-390
BACKGROUND The timing and duration of letrozole administration was designed to encompass the majority of postnatal development in the rat with the intent of evaluating the potential for a broad range of effects but with emphasis on expected effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02cedd98fde6fc7fd2a41fe881c388ef
https://doi.org/10.1002/bdrb.21080
https://doi.org/10.1002/bdrb.21080
Autor:
Paul Vancutsem, Marc DeCristofaro, Salah-Dine Chibout, Armin Wolf, Tao Wang, M. Craig Keselica, Francois Pognan, Marion Wiesmann, Elizabeth Skuba, Maria Papoutsi, Judit Markovits, Robert H. Spaet, James Sutton, Pierre Moulin, William Kluwe, Lew Petryk
Publikováno v:
International Journal of Toxicology. 30:300-312
This article addresses the issue of miscorrelation between hepatic injury biomarkers and histopathological findings in the drug development context. Our studies indicate that the use of toxicogenomics can aid in the drug development decision-making p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1062438dffe42d85f393c4f2612c2ecb
https://doi.org/10.1177/1091581811401920
https://doi.org/10.1177/1091581811401920
Autor:
Louise, Pouliot, Marilynn, Schneider, Marc, DeCristofaro, Rana, Samadfam, Susan Y, Smith, David A, Beckman
Publikováno v:
Birth defects research. Part B, Developmental and reproductive toxicology. 98(5)
The timing and duration of letrozole administration was designed to encompass the majority of postnatal development in the rat with the intent of evaluating the potential for a broad range of effects but with emphasis on expected effects on skeletal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc128b1a6c752d697901446527b3a122
https://pubmed.ncbi.nlm.nih.gov/24323897
https://pubmed.ncbi.nlm.nih.gov/24323897
Autor:
Kellye K. Daniels, Marc DeCristofaro
Publikováno v:
Essential Concepts in Toxicogenomics ISBN: 9781588296382
In the area of toxicology, the subdiscipline of toxicogenomics has emerged, which is the use of genome-scale mRNA expression profiling to monitor responses to adverse xenobiotic exposure. Toxicogenomics is being investigated for use in the triage of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f311938379e87271fa6f0ccd092446
https://doi.org/10.1007/978-1-60327-048-9_9
https://doi.org/10.1007/978-1-60327-048-9_9
