Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marc De Bast"'
Autor:
Marc De Bast, Emmanuel Coche, Birgit Weynand, John Aldo Lee, Valérie Lacroix, Marie Wanet, Xavier Geets, Vincent Grégoire, Alain Poncelet
Publikováno v:
Radiotherapy and Oncology. 98:117-125
PURPOSE: The aim of this study was to validate a gradient-based segmentation method for GTV delineation on FDG-PET in NSCLC through surgical specimen, in comparison with threshold-based approaches and CT. MATERIALS AND METHODS: Ten patients with stag
Autor:
Pierre Mahy, Vincent Grégoire, Daniel Labar, Marc De Bast, J. Gillart, Karin Haustermans, Arnaud Cheguillaume, Tjibbe de Groot
Publikováno v:
Radiotherapy and Oncology. 89:353-360
BACKGROUND AND PURPOSE: [(18)F]-EF3 allows non-invasive detection of hypoxia. In the framework of its validation, we aimed at comparing its pharmacokinetics, biodistribution, metabolism and specificity for hypoxia with the hypoxia tracer [(18)F]-FMIS
Autor:
Daniel Labar, Marc De Bast, Nicolas Christian, Pierre Mahy, Vincent Grégoire, John Aldo Lee, Anne Bol
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 34:1348-1354
PURPOSE: The 2-(2-nitroimidazol-1-yl)-N-(3,3,3-trifluoropropyl)acetamide (EF3) is a 2-nitroimidazole derivative which undergoes bioreductive activation under hypoxic conditions. Using the PET tracer [18F]EF3 in mice, tumour-to-muscle ratios ranging f
Autor:
Marc De Bast, Pierre Mahy, Pierre Scalliet, Vincent Grégoire, John Gueulette, Cameron J. Koch, Bernard Gallez
Publikováno v:
Radiotherapy and Oncology. 67:53-61
BACKGROUND AND PURPOSE: The primary objective of this study was to establish in vivo the relationship between 2-2-nitro-1H-imidazol-1yl-N-(2,2,3,3,3-pentafluoropropyl)-acetamide (EF5) adduct formation and intratumoral oxygen concentrations measured b
Autor:
Nicolas Christian, Marc De Bast, John Aldo Lee, Stéphanie Deheneffe, Daniel Labar, Vincent Grégoire, Anne Bol
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 97(2)
INTRODUCTION: Fluorodeoxyglucose (FDG) has been reported as a surrogate tracer to measure tumor hypoxia with positron emission tomography (PET). The hypothesis is that there is an increased uptake of FDG under hypoxic conditions secondary to enhanced
Autor:
Anne Bol, Nicolas Christian, Marc De Bast, Bénédicte F. Jordan, Vincent Grégoire, John Aldo Lee
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 91(1)
PURPOSE: Biological image-guided radiotherapy aims at specifically irradiating biologically relevant sub-volumes within the tumor, as determined for instance by PET imaging. This approach requires that PET imaging be sensitive and specific enough to
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 87(1)
Biological image-guided radiotherapy requires that PET accurately identifies biologically relevant sub-volumes within a tumor. In this framework, an immobilization device was developed to study multi-imaging (CT, micro-MRI, micro-PET, and autoradiogr
Autor:
M Bruniaux, M Octave-Prignot, Pierre Scalliet, Vincent Grégoire, Jean-François Rosier, Blanche M. De Coster, Marc De Bast
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 63(3)
BACKGROUND: Gemcitabine (dFdC, 2',2'-difluorodeoxycytidine) is a deoxycytidine nucleoside analog which has a marked effect on several enzymes involved in DNA synthesis and repair. Gemcitabine has been tested as a radiosensitizer in various biological
Autor:
Marc De Bast, Pierre Scalliet, Vincent Grégoire, M. Octaveprignot, Jean-Claude Rosier, B M De Coster, M Bruniaux, Marc Beauduin
Publikováno v:
International journal of radiation biology. 75(2)
The present study investigated in vitro radio-enhancement by gemcitabine (dFdC) in two head and neck squamous cell carcinomas with different intrinsic cellular radiosensitivity.Radiosensitive (SCC61, SF2=0.16) and radioresistant (SQD9, SF2=0.49) huma