Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Marc Dalod"'
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors
Autor:
Lucía López, Luciano Gastón Morosi, Federica La Terza, Pierre Bourdely, Giuseppe Rospo, Roberto Amadio, Giulia Maria Piperno, Valentina Russo, Camilla Volponi, Simone Vodret, Sonal Joshi, Francesca Giannese, Dejan Lazarevic, Giovanni Germano, Patrizia Stoitzner, Alberto Bardelli, Marc Dalod, Luigia Pace, Nicoletta Caronni, Pierre Guermonprez, Federica Benvenuti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cross-presentation by type 1 DCs (cDC1) is critical to induce and sustain antitumoral CD8 T cell responses to model antigens, in various tumor settings. However, the impact of cross-presenting cDC1 and the potential of DC-based therapies in
Externí odkaz:
https://doaj.org/article/f7c6a9ff87e544acbdd02715c577e12b
Autor:
Prashanth K Kandalla, Julien Subburayalu, Clément Cocita, Bérengère deLaval, Elena Tomasello, Johanna Iacono, Jessica Nitsche, Maria M Canali, Wilfried Cathou, Gilles Bessou, Noushin Mossadegh‐Keller, Caroline Huber, Guy Mouchiroud, Roland P Bourette, Marie‐France Grasset, Martin Bornhäuser, Sandrine Sarrazin, Marc Dalod, Michael H Sieweke
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp n/a-n/a (2023)
Abstract Therapies reconstituting autologous antiviral immunocompetence may represent an important prophylaxis and treatment for immunosuppressed individuals. Following hematopoietic cell transplantation (HCT), patients are susceptible to Herpesvirid
Externí odkaz:
https://doaj.org/article/09b31254506a4af3b59dd5b3a87d1220
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/580a54200d454cba918543f6338e2fbc
Autor:
Carla Gouin, Thien-Phong Vu Manh, Luc Jouneau, Claudia Bevilacqua, Julien De Wolf, Matthieu Glorion, Laurent Hannouche, Céline Urien, Jérôme Estephan, Antoine Roux, Antoine Magnan, Morgan Le Guen, Bruno Da Costa, Christophe Chevalier, Delphyne Descamps, Isabelle Schwartz-Cornil, Marc Dalod, Edouard Sage
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In response to the increasing demand for lung transplantation, ex vivo lung perfusion (EVLP) has extended the number of suitable donor lungs by rehabilitating marginal organs. However despite an expanding use in clinical practice, the responses of th
Externí odkaz:
https://doaj.org/article/1f5a0c0da38f453cb4a6157f1ef9226b
Autor:
Anastasiia Gainullina, Denis A. Mogilenko, Li-Hao Huang, Helena Todorov, Vipin Narang, Ki-Wook Kim, Lim Sheau Yng, Andrew Kent, Baosen Jia, Kumba Seddu, Karen Krchma, Jun Wu, Karine Crozat, Elena Tomasello, Regine Dress, Peter See, Charlotte Scott, Sophie Gibbings, Geetika Bajpai, Jigar V. Desai, Barbara Maier, Sébastien This, Peter Wang, Stephanie Vargas Aguilar, Lucie Poupel, Sébastien Dussaud, Tyng-An Zhou, Veronique Angeli, J. Magarian Blander, Kyunghee Choi, Marc Dalod, Ivan Dzhagalov, Emmanuel L. Gautier, Claudia Jakubzick, Kory Lavine, Michail S. Lionakis, Helena Paidassi, Michael H. Sieweke, Florent Ginhoux, Martin Guilliams, Christophe Benoist, Miriam Merad, Gwendalyn J. Randolph, Alexey Sergushichev, Maxim N. Artyomov
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112046- (2023)
Summary: The diversity of mononuclear phagocyte (MNP) subpopulations across tissues is one of the key physiological characteristics of the immune system. Here, we focus on understanding the metabolic variability of MNPs through metabolic network anal
Externí odkaz:
https://doaj.org/article/8a6a390493e44f40a7321fccee2cd51c
Autor:
Sonia Ghilas, Marc Ambrosini, Jean-Charles Cancel, Carine Brousse, Marion Massé, Hugues Lelouard, Marc Dalod, Karine Crozat
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103059- (2021)
Summary: Successful immune responses rely on a regulated delivery of the right signals to the right cells at the right time. Here we show that natural killer (NK) and dendritic epidermal γδ T cells (DETCs) use similar mechanisms to spatiotemporally
Externí odkaz:
https://doaj.org/article/d54b1b8a1b4c4075baf41ba89bea284f
Autor:
Michael Valente, Nils Collinet, Thien-Phong Vu Manh, Dimitri Popoff, Khalissa Rahmani, Karima Naciri, Gilles Bessou, Rejane Rua, Laurine Gil, Cyrille Mionnet, Pierre Milpied, Elena Tomasello, Marc Dalod
Publikováno v:
Nature Immunology. 24:714-728
Plasmacytoid dendritic cells (pDCs) are the main source of type I interferon (IFN-I) during viral infections. Their other functions are debated, due to a lack of tools to identify and target them in vivo without affecting pDC-like cells and transitio
Autor:
Raphaël Mattiuz, Carine Brousse, Marc Ambrosini, Jean‐Charles Cancel, Gilles Bessou, Julie Mussard, Amélien Sanlaville, Christophe Caux, Nathalie Bendriss‐Vermare, Jenny Valladeau‐Guilemond, Marc Dalod, Karine Crozat
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 7, Pp n/a-n/a (2021)
Abstract Objectives To better understand how immune responses may be harnessed against breast cancer, we investigated which immune cell types and signalling pathways are required for spontaneous control of a mouse model of mammary adenocarcinoma. Met
Externí odkaz:
https://doaj.org/article/46b93295952c43ec864f593fc141e98b
Autor:
Lukas Heger, Thomas P. Hofer, Venetia Bigley, I. Jolanda M. de Vries, Marc Dalod, Diana Dudziak, Loems Ziegler-Heitbrock
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Currently three bona fide dendritic cell (DC) types are distinguished in human blood. Herein we focus on type 2 DCs (DC2s) and compare the three defining markers CD1c, CD172, and CD301. When using CD1c to define DC2s, a CD14+ and a CD14− subset can
Externí odkaz:
https://doaj.org/article/d5b6497587ab4e1f84ffb381a689010b
Autor:
Camille Wagner, Johnny Bonnardel, Clément Da Silva, Lionel Spinelli, Cynthia Arroyo Portilla, Julie Tomas, Margaux Lagier, Lionel Chasson, Marion Masse, Marc Dalod, Alexandre Chollat-Namy, Jean-Pierre Gorvel, Hugues Lelouard
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: The monocyte-derived phagocytes termed LysoDCs are hallmarks of Peyer’s patches, where their main function is to sample intestinal microorganisms. Here, we study their differentiation pathways in relation with their sampling, migratory, an
Externí odkaz:
https://doaj.org/article/6a3f915947a14b7c93ab93f7f0f6f573