Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Marc Cougnon"'
Autor:
Michel Tauc, Marc Cougnon, Romain Carcy, Nicolas Melis, Thierry Hauet, Luc Pellerin, Nicolas Blondeau, Didier F. Pisani
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract Since the demonstration of its involvement in cell proliferation, the eukaryotic initiation factor 5A (eIF5A) has been studied principally in relation to the development and progression of cancers in which the isoform A2 is mainly expressed.
Externí odkaz:
https://doaj.org/article/b37c878fff754435ae08d83cd4573bc1
Autor:
Marc Cougnon, Romain Carcy, Nicolas Melis, Isabelle Rubera, Christophe Duranton, Karine Dumas, Jean-François Tanti, Catherine Pons, Nicolas Soubeiran, Marina Shkreli, Thierry Hauet, Luc Pellerin, Sébastien Giraud, Nicolas Blondeau, Michel Tauc, Didier F. Pisani
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Abstract Inhibition of the eukaryotic initiation factor 5A activation by the spermidine analogue GC7 has been shown to protect proximal cells and whole kidneys against an acute episode of ischaemia. The highlighted mechanism involves a metabolic swit
Externí odkaz:
https://doaj.org/article/1c2ead5a19d749b38f91c58c3d62652c
Autor:
Denis Doyen, Mallorie Poët, Gisèle Jarretou, Didier F. Pisani, Michel Tauc, Marc Cougnon, Mederic Argentina, Yann Bouret, Laurent Counillon
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Intracellular pH is a vital parameter that is maintained close to neutrality in all mammalian cells and tissues and acidic in most intracellular compartments. After presenting the main techniques used for intracellular an vesicular pH measurements we
Externí odkaz:
https://doaj.org/article/33a0ff5d01784466b97fa54cc1d0b83b
Autor:
Nicolas Melis, Isabelle Rubera, Sebastien Giraud, Marc Cougnon, Christophe Duranton, Mallorie Poet, Gisèle Jarretou, Raphaël Thuillier, Laurent Counillon, Thierry Hauet, Luc Pellerin, Michel Tauc, Didier F. Pisani
Publikováno v:
Cells, Vol 12, Iss 3, p 409 (2023)
Through kidney transplantation, ischemia/reperfusion is known to induce tissular injury due to cell energy shortage, oxidative stress, and endoplasmic reticulum (ER) stress. ER stress stems from an accumulation of unfolded or misfolded proteins in th
Externí odkaz:
https://doaj.org/article/05f32dd3ce7f408ab5c5f61bf0693e37
Autor:
Nicolas Melis, Romain Carcy, Isabelle Rubera, Marc Cougnon, Christophe Duranton, Michel Tauc, Didier F. Pisani
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 152 (2021)
Lesions issued from the ischemia/reperfusion (I/R) stress are a major challenge in human pathophysiology. Of human organs, the kidney is highly sensitive to I/R because of its high oxygen demand and poor regenerative capacity. Previous studies have s
Externí odkaz:
https://doaj.org/article/025ff1815b274f40ace4fb1eaa4aee49
Autor:
Jonas Friard, Michel Tauc, Marc Cougnon, Vincent Compan, Christophe Duranton, Isabelle Rubera
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Chloride channels play an essential role in a variety of physiological functions and in human diseases. Historically, the field of chloride channels has long been neglected owing to the lack of powerful selective pharmacological agents that are neede
Externí odkaz:
https://doaj.org/article/aadde1aa6aed4f788b064e7e7c860fe0
Autor:
Danielle Tondelier, Franck Brouillard, Joanna Lipecka, Régis Labarthe, Moëz Bali, Marie-Ayliette Costa De Beauregard, Tanja Torossi, Marc Cougnon, Aleksander Edelman, Maryvonne Baudouin-Legros
Publikováno v:
Mediators of Inflammation, Vol 8, Iss 4-5, Pp 219-227 (1999)
Cystic fibrosis (CF) is caused by mutations in the CF gene, which encodes CF transmembrane conductance regulator protein (CFTR), a transmembrane protein that acts as a cAMP-regulated chloride channel. The disease is characterized by inflammation but
Externí odkaz:
https://doaj.org/article/fd397c2a1fa842c49bb98b3c5f4f4a5b
Autor:
Michel Tauc, Laurent Counillon, Antoine Sicard, Romain Carcy, Thierry Hauet, Didier F. Pisani, Manon Durandy, Marc Cougnon, Mallorie Poët, Nicolas Blondeau
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, 2021, 169, pp.258-270. ⟨10.1016/j.freeradbiomed.2021.04.023⟩
Free Radical Biology and Medicine, Elsevier, 2021, 169, pp.258-270. ⟨10.1016/j.freeradbiomed.2021.04.023⟩
Free Radical Biology and Medicine, 2021, 169, pp.258-270. ⟨10.1016/j.freeradbiomed.2021.04.023⟩
Free Radical Biology and Medicine, Elsevier, 2021, 169, pp.258-270. ⟨10.1016/j.freeradbiomed.2021.04.023⟩
Disorders characterized by ischemia/reperfusion (I/R) are the most common causes of debilitating diseases and death in stroke, cardiovascular ischemia, acute kidney injury or organ transplantation. In the latter example the I/R step defines both the
Autor:
Michel Tauc, Jonas Friard, Marc Cougnon, Didier F. Pisani, Christophe Duranton, Isabelle Rubera, Alain Corinus
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2019, 10 (12), ⟨10.1038/s41419-019-2167-z⟩
Cell Death and Disease, Vol 10, Iss 12, Pp 1-13 (2019)
Cell Death & Disease
Cell Death and Disease, Nature Publishing Group, 2019, 10 (12), ⟨10.1038/s41419-019-2167-z⟩
Cell Death and Disease, Vol 10, Iss 12, Pp 1-13 (2019)
Cell Death & Disease
Volume-regulated anion channels (VRAC) are chloride channels activated in response to osmotic stress to regulate cellular volume and also participate in other cellular processes, including cell division and cell death. Recently, members of the LRRC8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a20e4672a8cf6f2e24814b233c1e90
https://hal.archives-ouvertes.fr/hal-02918200
https://hal.archives-ouvertes.fr/hal-02918200
Autor:
Sandra Lacas-Gervais, Baharia Mograbi, Amine Belaid, Christophe Duranton, Marc Cougnon, Sébastien Giraud, Christian Frelin, Didier F. Pisani, Michel Tauc, Nicolas Melis, Nicolas Blondeau, Paul Vigne, Konstantina Fragaki, Stephan M. Huber, Thierry Hauet, Isabelle Rubera
Publikováno v:
Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, American Society of Nephrology, 2017, 28 (3), pp.811-822. ⟨10.1681/ASN.2016010012⟩
Journal of the American Society of Nephrology, American Society of Nephrology, 2017, 28 (3), pp.811-822. ⟨10.1681/ASN.2016010012⟩
International audience; The eukaryotic initiation factor 5A (eIF5A), which is highly conserved throughout evolution, has the unique characteristic of post-translational activation through hypusination. This modification is catalyzed by two enzymatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6458b8364eefd67670a482c6116d32
https://europepmc.org/articles/PMC5328152/
https://europepmc.org/articles/PMC5328152/