Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marc Chikhani"'
Autor:
Sonal Mistry, Anup Das, Sina Saffaran, Nadir Yehya, Timothy E. Scott, Marc Chikhani, John G. Laffey, Jonathan G. Hardman, Luigi Camporota, Declan G. Bates
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Airway pressure release ventilation (APRV) is widely available on mechanical ventilators and has been proposed as an early intervention to prevent lung injury or as a rescue therapy in the management of refractory hypoxemia. Drivi
Externí odkaz:
https://doaj.org/article/9e0a79736aab4245a04b09c4885e6681
Autor:
Liam Weaver, Anup Das, Sina Saffaran, Nadir Yehya, Timothy E. Scott, Marc Chikhani, John G. Laffey, Jonathan G. Hardman, Luigi Camporota, Declan G. Bates
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Background There is on-going controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure.
Externí odkaz:
https://doaj.org/article/f000987f12f844c988b045c84903b823
Autor:
Mark Borthwick, Danny McAuley, John Warburton, Rohan Anand, Judy Bradley, Bronwen Connolly, Bronagh Blackwood, Brenda O’Neill, Marc Chikhani, Paul Dark, Murali Shyamsundar, MICCS collaborators—Critical Care Pharmacists
Publikováno v:
PeerJ, Vol 8, p e8828 (2020)
Background Mechanical ventilation for acute respiratory failure is one of the most common indications for admission to intensive care units (ICUs). Airway mucus clearance is impaired in these patients medication, impaired mucociliary motility, increa
Externí odkaz:
https://doaj.org/article/a1b91a6aa7c74dc98de573be1b9ac86a
Autor:
Liam Weaver, Anup Das, Sina Saffaran, Nadir Yehya, Marc Chikhani, Timothy E. Scott, John G. Laffey, Jonathan G. Hardman, Luigi Camporota, Declan G. Bates
Publikováno v:
British Journal of Anaesthesia. 128:1052-1058
Background: Optimal respiratory support in early COVID-19 pneumonia is controversial and remains unclear. Using computational modelling, we examined whether lung injury might be exacerbated in early COVID-19 by assessing the impact of conventional ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58b359781ff2e40e686cb3400025048
https://doi.org/10.1016/j.bja.2022.02.037
https://doi.org/10.1016/j.bja.2022.02.037
Autor:
Liam Weaver, Sina Saffaran, Marc Chikhani, John G. Laffey, Tim E. Scott, Luigi Camporota, Jonathan G. Hardman, Declan G. Bates
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2022
The magnitude of inspiratory effort relief within the first 2 hours of non-invasive ventilation for hypoxic respiratory failure was shown in a recent exploratory clinical study to be an early and accurate predictor of outcome at 24 hours. We simulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f544f99fedd697b56ff165cf846b969
https://pubmed.ncbi.nlm.nih.gov/36085857
https://pubmed.ncbi.nlm.nih.gov/36085857
Autor:
Sonal Mistry, Bindi S. Brook, Sina Saffaran, Marc Chikhani, David M. Hannon, John G. Laffey, Tim E. Scott, Luigi Camporota, Jonathan G. Hardman, Declan G. Bates
Publikováno v:
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
We present new results validating the capability of a high-fidelity computational simulator to accurately predict the responses of individual patients with acute respiratory distress syndrome to changes in mechanical ventilator settings. 26 pairs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9c15ab2398c6bbdac3c0e3a629aca5
https://doi.org/10.1109/embc48229.2022.9871182
https://doi.org/10.1109/embc48229.2022.9871182
Autor:
Marc Chikhani, Declan G. Bates, Sina Saffaran, John G. Laffey, Jonathan G. Hardman, Nadir Yehya, Anup Das, Luigi Camporota, Liam Weaver, Timothy E. Scott
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-8 (2021)
Annals of Intensive Care
Annals of Intensive Care
Background There is on-going controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d811067a95b3d2cc2cb4bcd9749cdce
Publikováno v:
British Journal of Anaesthesia. 122:395-401
Background Apnoeic oxygenation can come close to matching the oxygen demands of the apnoeic patient but does not facilitate carbon dioxide (CO2) elimination, potentially resulting in dangerous hypercapnia. Numerous studies have shown that high-flow n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652d84132c37d5ccdb6b9f8de0928129
https://doi.org/10.1016/j.bja.2018.11.012
https://doi.org/10.1016/j.bja.2018.11.012
Autor:
Declan G. Bates, Luigi Camporota, Anup Das, Jonathan G. Hardman, Nadir Yehya, Liam Weaver, John G. Laffey, Sina Saffaran, Timothy E. Scott, Marc Chikhani
BackgroundThere is on-going controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28864f7ca6a3eae24ab717555b68b20c
https://doi.org/10.1101/2021.03.17.21253788
https://doi.org/10.1101/2021.03.17.21253788
BackgroundThe novel coronavirus SARS-CoV-2 and associated multisystem disease COVID-19 originated in Wuhan, China in December 2019. The resultant pandemic has resulted in an unprecedented strain on healthcare services around the world, including the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98cc6510722bd1839f8e6214c539dbd3
https://doi.org/10.21203/rs.3.rs-95525/v1
https://doi.org/10.21203/rs.3.rs-95525/v1