Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marc Charabati"'
Autor:
Alba Sánchez-Fernández, Stephanie Zandee, Mauricio Mastrogiovanni, Marc Charabati, Homero Rubbo, Alexandre Prat, Rubèn López-Vales
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Resolution of inflammation is an active and regulated process that leads to the clearance of cell debris and immune cells from the challenged tissue, facilitating the recovery of homeostasis. This physiological response is coordin
Externí odkaz:
https://doaj.org/article/cdf4d8835a9a4105982a5453884f0a42
Autor:
Florian Bernard-Patrzynski, Marc-André Lécuyer, Ina Puscas, Imane Boukhatem, Marc Charabati, Lyne Bourbonnière, Charles Ramassamy, Grégoire Leclair, Alexandre Prat, V Gaëlle Roullin
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226302 (2019)
Primary cell isolation from the central nervous system (CNS) has allowed fundamental understanding of blood-brain barrier (BBB) properties. However, poorly described isolation techniques or suboptimal cellular purity has been a weak point of some pub
Externí odkaz:
https://doaj.org/article/5124970efe8d4019966a3720a73640a9
Publikováno v:
Cell
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system afflicting nearly three million individuals worldwide. Neuroimmune interactions between glial, neural, and immune cells play important roles in M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387965deaafc79632a9c34dcaf9bee62
https://doi.org/10.1016/j.cell.2023.03.008
https://doi.org/10.1016/j.cell.2023.03.008
Autor:
Iain C. Clark, Michael A. Wheeler, Hong-Gyun Lee, Zhaorong Li, Liliana M. Sanmarco, Shravan Thaploo, Carolina M. Polonio, Seung Won Shin, Giulia Scalisi, Amy R. Henry, Joseph M. Rone, Federico Giovannoni, Marc Charabati, Camilo Faust Akl, Dulce M. Aleman, Stephanie E. J. Zandee, Alexandre Prat, Daniel C. Douek, Eli A. Boritz, Francisco J. Quintana, Adam R. Abate
Publikováno v:
Nature, vol 614, iss 7947
Nature
Nature
Multiple sclerosis is a chronic inflammatory disease of the central nervous system1. Astrocytes are heterogeneous glial cells that are resident in the central nervous system and participate in the pathogenesis of multiple sclerosis and its model expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4aa6e11d1866a7910d272fce76dd090
https://doi.org/10.1038/s41586-022-05613-0
https://doi.org/10.1038/s41586-022-05613-0
Autor:
Marc Charabati, Stephanie Zandee, Antoine P Fournier, Olivier Tastet, Karine Thai, Roxaneh Zaminpeyma, Marc-André Lécuyer, Lyne Bourbonnière, Sandra Larouche, Wendy Klement, Camille Grasmuck, Fiona Tea, Bettina Zierfuss, Ali Filali-Mouhim, Robert Moumdjian, Alain Bouthillier, Romain Cayrol, Evelyn Peelen, Nathalie Arbour, Catherine Larochelle, Alexandre Prat
Publikováno v:
Brain. 146:1483-1495
The trafficking of autoreactive leucocytes across the blood–brain barrier endothelium is a hallmark of multiple sclerosis pathogenesis. Although the blood–brain barrier endothelium represents one of the main CNS borders to interact with the infil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc336d30eeb0f8febc94fb723d174b8
https://doi.org/10.1093/brain/awac389
https://doi.org/10.1093/brain/awac389
Autor:
Michael A. Wheeler, Iain C. Clark, Hong-Gyun Lee, Zhaorong Li, Mathias Linnerbauer, Joseph M. Rone, Manon Blain, Camilo Faust Akl, Gavin Piester, Federico Giovannoni, Marc Charabati, Joon-Hyuk Lee, Yoon-Chul Kye, Joshua Choi, Liliana M. Sanmarco, Lena Srun, Elizabeth N. Chung, Lucas E. Flausino, Brian M. Andersen, Veit Rothhammer, Hiroshi Yano, Tomer Illouz, Stephanie E. J. Zandee, Carolin Daniel, David Artis, Marco Prinz, Adam R. Abate, Vijay K. Kuchroo, Jack P. Antel, Alexandre Prat, Francisco J. Quintana
Publikováno v:
Science
Cell–cell interactions in the central nervous system play important roles in neurologic diseases. However, little is known about the specific molecular pathways involved, and methods for their systematic identification are limited. Here, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716c964e8fd9ff8c09dd7ebbf702e31d
https://europepmc.org/articles/PMC10066924/
https://europepmc.org/articles/PMC10066924/
Autor:
Sienna S. Drake, Marc Charabati, Tristan Simas, Yu Kang T. Xu, Etienne J. P. Maes, Shan Shan Shi, Jack Antel, Alexandre Prat, Barbara Morquette, Alyson E. Fournier
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14811
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease driven by inflammation and demyelination in the brain, spinal cord, and optic nerve. Optic neuritis, characterized by inflammation and demyelination of the optic nerve, is a sympt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe5e2f648d572e99e6dc134c874293e
Autor:
Antoine Philippe Fournier, Olivier Tastet, Marc Charabati, Chloé Hoornaert, Lyne Bourbonnière, Wendy Klement, Sandra Larouche, Fiona Tea, Yu Chang Wang, Catherine Larochelle, Nathalie Arbour, Jiannis Ragoussis, Stephanie Zandee, Alexandre Prat
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 10(1)
Background and ObjectivesMultiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease characterized by infiltration of immune cells in multifocal areas of the CNS. The specific molecular processes allowing autoreactive immune cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e52aa9f439f6ff33b8d1764806665c
https://pubmed.ncbi.nlm.nih.gov/36446612
https://pubmed.ncbi.nlm.nih.gov/36446612
Publikováno v:
Multiple Sclerosis Journal. 26:1448-1458
Helminthic worms are ancestral members of the intestinal ecosystem that have been largely eradicated from the general population in industrialized countries. Immunomodulatory mechanisms induced by some helminths mediate a “truce” between the mamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99417d8271f79b3c5ff80e1dad1cc71e
https://doi.org/10.1177/1352458519899040
https://doi.org/10.1177/1352458519899040
Publikováno v:
Trends in Pharmacological Sciences. 41:42-54
Nanoparticulate carriers, often referred to as nanoparticles (NPs), represent an important pharmacological advance for drug protection and tissue-specific drug delivery. Accessing the central nervous system (CNS), however, is a complex process regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec11f1e5d387088a34e1c7b8f579dc0
https://doi.org/10.1016/j.tips.2019.11.001
https://doi.org/10.1016/j.tips.2019.11.001