Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marc Cerrada-Gimenez"'
Autor:
Sreeraj Kuruppilakath Manikandan, Ann Logan, Marc Cerrada-Gimenez, Laurence Fitzhenry, Lee Coffey, Simon Kaja, Sweta Rani
Publikováno v:
Life, Vol 13, Iss 12, p 2236 (2023)
Wet age-related macular degeneration (wAMD) is a chronic inflammation-associated neurodegenerative disease affecting the posterior part of the eye in the aging population. Aging results in the reduced functionality of cells and tissues, including the
Externí odkaz:
https://doaj.org/article/5ccf5828ec4b4f4185b20fd22c98209d
Autor:
Harri Elamaa, Minna Kihlström, Emmi Kapiainen, Mika Kaakinen, Ilkka Miinalainen, Symantas Ragauskas, Marc Cerrada-Gimenez, Satu Mering, Marjut Nätynki, Lauri Eklund
Publikováno v:
eLife, Vol 7 (2018)
The maintenance of fluid homeostasis is necessary for function of the neural retina; however, little is known about the significance of potential fluid management mechanisms. Here, we investigated angiopoietin-4 (Angpt4, also known as Ang3), a poorl
Externí odkaz:
https://doaj.org/article/336523bacb18459e80fe0bee7916a2e3
Autor:
Jost B. Jonas, Marc Cerrada-Gimenez, Giedrius Kalesnykas, Mukharram M. Bikbov, Symantas Ragauskas, Timur A. Khalimov
Publikováno v:
International Ophthalmology
Introduction To examine the compatibility of intravitreally injected epidermal growth factor (EGF) and amphiregulin as EGF family member. Methods Four rabbits (age: 4 months; body weight: 2.5 kg) received three intravitreal injections of EGF (100 ng)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b6330957c94337c85609cfdc012201
https://doi.org/10.1007/s10792-021-01761-w
https://doi.org/10.1007/s10792-021-01761-w
Autor:
Karolina Losenkova, Akira Takeda, Symantas Ragauskas, Marc Cerrada-Gimenez, Maria Vähätupa, Simon Kaja, Marius L. Paul, Constanze C. Schmies, Georg Rolshoven, Christa E. Müller, Jouko Sandholm, Sirpa Jalkanen, Giedrius Kalesnykas, Gennady G. Yegutkin
Publikováno v:
Cellular and Molecular Life Sciences. 79
ATP and adenosine have emerged as important signaling molecules involved in vascular remodeling, retinal functioning and neurovascular coupling in the mammalian eye. However, little is known about the regulatory mechanisms of purinergic signaling in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9e47fff3564e83ba322c099857abf2
https://doi.org/10.1007/s00018-022-04187-4
https://doi.org/10.1007/s00018-022-04187-4
Autor:
Niina Jääskeläinen, Tero A. H. Järvinen, Marc Cerrada-Gimenez, Giedrius Kalesnykas, Rubina Thapa, Maria Vähätupa, Hannele Uusitalo-Jarvinen
Publikováno v:
Journal of visualized experiments : JoVE. (163)
One of the commonly used models for ischemic retinopathies is the oxygen-induced retinopathy (OIR) model. Here we describe detailed protocols for the OIR model induction and its readouts in both mice and rats. Retinal neovascularization is induced in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60e7af1bc161dbf4a560c3be290ed15
https://pubmed.ncbi.nlm.nih.gov/33016936
https://pubmed.ncbi.nlm.nih.gov/33016936
Autor:
Jussi Rytkönen, Kimmo Lehtimäki, Marc Cerrada-Gimenez, Pekka Poutiainen, Timo Bragge, Jukka Puoliväli, Jacob T. Cain, Tyler B. Johnson, Giedrius Kalesnykas, Antti Nurmi, Samantha Davis, Jill M. Weimer
Publikováno v:
Molecular Genetics and Metabolism. 129:S97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::941763291e1fef333be603ba292100a7
https://doi.org/10.1016/j.ymgme.2019.11.244
https://doi.org/10.1016/j.ymgme.2019.11.244
Autor:
Harri Elamaa, Ilkka Miinalainen, Emmi Kapiainen, Satu Mering, Mika Kaakinen, Lauri Eklund, Marjut Nätynki, Marc Cerrada-Gimenez, Symantas Ragauskas, Minna Kihlström
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99d1526ab16b1e71e62914e05a98a335
https://doi.org/10.7554/elife.37776.034
https://doi.org/10.7554/elife.37776.034
Autor:
Alba Casellas, Marc Cerrada-Gimenez, Maija Tusa, Eija Pirinen, Fatima Bosch, Leena Alhonen, Marta Moya
Publikováno v:
Transgenic Research. 21:843-853
Ubiquitous activation of polyamine catabolism has been demonstrated to have protective effects in mice on fat accumulation and insulin sensitivity/glucose tolerance in, both, normal conditions and after a high fat diet. We have analyzed the endocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0905573d522b4344b74fc778fdda21e5
https://doi.org/10.1007/s11248-011-9579-6
https://doi.org/10.1007/s11248-011-9579-6
Autor:
Janne Weisell, Myung Hee Park, Mervi T. Hyvönen, Marc Cerrada-Gimenez, Jouko Vepsäläinen, Tuomo A. Keinänen, Leena Alhonen
Publikováno v:
Drug Metabolism and Disposition. 39:2242-2249
Triethylenetetramine (TETA) is an efficient copper chelator that has versatile clinical potential. We have recently shown that spermidine/spermine-N(1)-acetyltransferase (SSAT1), the key polyamine catabolic enzyme, acetylates TETA in vitro. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41ae504bd0b6ffedd5a45ee63531c9e
https://doi.org/10.1124/dmd.111.041798
https://doi.org/10.1124/dmd.111.041798
Autor:
Jouko Vepsäläinen, Marc Cerrada-Gimenez, Seppo Auriola, Merja R. Häkkinen, Tuomo A. Keinänen, Leena Alhonen
Publikováno v:
Amino Acids. 42:451-460
The study of polyamine flux, i.e. the circulating flow of polyamines through the interconnected biosynthetic and catabolic pathways, is of considerable interest because of the established links between the polyamine metabolism and many diseases, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162a2df34944527862851abb9a583b9f
https://doi.org/10.1007/s00726-011-1024-x
https://doi.org/10.1007/s00726-011-1024-x