Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marc C Liggins"'
Autor:
Marc C Liggins, Jessica L Flesher, Sohail Jahid, Priya Vasudeva, Victoria Eby, Shunsuke Takasuga, Junko Sasaki, Takehiko Sasaki, Raymond E Boissy, Anand K Ganesan
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007290 (2018)
PIKfyve, VAC14, and FIG4 form a complex that catalyzes the production of PI(3,5)P2, a signaling lipid implicated in process ranging from lysosome maturation to neurodegeneration. While previous studies have identified VAC14 and FIG4 mutations that le
Externí odkaz:
https://doaj.org/article/6d8395e8a22e45cc82e85a7db02d0084
Autor:
Alan M. O’Neill, Marc C. Liggins, Jason S. Seidman, Tran H. Do, Fengwu Li, Kellen J. Cavagnero, Tatsuya Dokoshi, Joyce Y. Cheng, Faiza Shafiq, Tissa R. Hata, Johann E. Gudjonsson, Robert L. Modlin, Richard L. Gallo
Publikováno v:
Sci Transl Med
Science translational medicine, vol 14, iss 632
Science translational medicine, vol 14, iss 632
Innate immune defense against deep tissue infection by Staphylococcus aureus is orchestrated by fibroblasts that become antimicrobial when triggered to differentiate into adipocytes. However, the role of this process in noninfectious human diseases i
Autor:
Marc C. Liggins, Nita H. Salzman, Richard L. Gallo, Jocelyn G. Olvera, John T. Chang, Bryn C. Taylor, Jason S Seidman, Tatsuya Dokoshi, Kellen J. Cavagnero, Rob Knight, Fengwu Li
Publikováno v:
J Clin Invest
The Journal of clinical investigation, vol 131, iss 21
The Journal of clinical investigation, vol 131, iss 21
Inflammatory disorders of the skin are frequently associated with inflammatory bowel diseases (IBDs). To explore mechanisms by which these organs communicate, we performed single-cell RNA-Seq analysis on fibroblasts from humans and mice with IBD. Thi
Publikováno v:
J Immunol
A subset of dermal fibroblasts undergo rapid differentiation into adipocytes in response to infection and acutely produce the cathelicidin antimicrobial peptide gene Camp. Vitamin A and other retinoids inhibit adipogenesis yet can show benefit to ski
Autor:
Richard L. Gallo, Marc C. Liggins, Tatsuya Dokoshi, George L. Sen, Teruaki Nakatsuji, Yu Sawada, Nikhil Nitin Kulkarni
Publikováno v:
Science immunology, vol 6, iss 59
Sci Immunol
Sci Immunol
The skin typically tolerates exposure to various microbes and chemicals in the environment. Here, we investigated how the epidermis maintains this innate immune tolerance to stimuli that are recognized by Toll-like receptors (TLRs). Loss of tolerance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d149e8175df57a15b8d0016b8ea81ccc
https://escholarship.org/uc/item/5db3p8h5
https://escholarship.org/uc/item/5db3p8h5
Autor:
George L. Sen, Nikhil Nitin Kulkarni, T. Nakatsuji, Richard L. Gallo, Tatsuya Dokoshi, Yu Sawada, Marc C. Liggins
Publikováno v:
Journal of Investigative Dermatology. 141:S37
Autor:
Richard L. Gallo, John T. Chang, Jason S. Seidman, Jocelyn G. Olvera, Rob Knight, Tatsuya Dokoshi, Kellen J. Cavagnero, Bryn C. Taylor, Marc C. Liggins
Publikováno v:
Journal of Investigative Dermatology. 141:S38
Autor:
George L. Sen, J. Jones, R.L. Gallo, Nikhil Nitin Kulkarni, Yu Sawada, Marc C. Liggins, Tatsuya Dokoshi, Teruaki Nakatsuji
Publikováno v:
Journal of Investigative Dermatology. 140:S42
Autor:
Jason S. Seidman, Michael R. Williams, Jocelyn G. Olvera, Rob Knight, John T. Chang, Tatsuya Dokoshi, R.L. Gallo, Marc C. Liggins, Bryn C. Taylor, Fengwu Li
Publikováno v:
Journal of Investigative Dermatology. 140:S26
Autor:
Nadja B. Cech, Stephen K. Costa, Daniel A. Todd, Alan M. O’Neill, Livia S. Zaramela, Karsten Zengler, James A. Sanford, Alexander R. Horswill, Teruaki Nakatsuji, Shadi Khalil, Richard L. Gallo, Michael R. Williams, Ambrose L. Cheung, Marc C. Liggins, Heather L. Winter
Publikováno v:
Science translational medicine. 11(490)
Colonization of the skin by Staphylococcus aureus is associated with exacerbation of atopic dermatitis (AD), but any direct mechanism through which dysbiosis of the skin microbiome may influence the development of AD is unknown. Here, we show that pr