Continued selection on cryptic SARS-CoV-2 observed in Missouri wastewater.

Autor: Devon A Gregory, Clayton Rushford, Torin Hunter, Chung-Ho Lin, Christie Darby, Nicole Niehues, Elizabeth Semkiw, Melissa Reynolds, Jeff Wenzel, Marc C Johnson

Publikováno v: PLoS Pathogens, Vol 19, Iss 12, p e1011688 (2023)

Deep sequencing of wastewater to detect SARS-CoV-2 has been used during the COVID-19 pandemic to monitor viral variants as they appear and circulate in communities. SARS-CoV-2 lineages of an unknown source that have not been detected in clinical samp

Externí odkaz: https://doaj.org/article/68ab7275cafd457d8af5571704b21651

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles.

Autor: Clifton L Ricana, Terri D Lyddon, Robert A Dick, Marc C Johnson

Publikováno v: PLoS Pathogens, Vol 16, Iss 8, p e1008646 (2020)

Inositol hexakisphosphate (IP6) potently stimulates HIV-1 particle assembly in vitro and infectious particle production in vivo. However, knockout cells lacking inositol-pentakisphosphate 2-kinase (IPPK-KO), the enzyme that produces IP6 by phosphoryl

Externí odkaz: https://doaj.org/article/0a2d2c5105324312b027eeceb972515d

Functional complementation of a model target to study Vpu sensitivity.

Autor: Sanath Kumar Janaka, Jared Faurot, Marc C Johnson

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e68507 (2013)

HIV-1 forms infectious particles with Murine Leukemia virus (MLV) Env, but not with the closely related Gibbon ape Leukemia Virus (GaLV) Env. We have determined that the incompatibility between HIV-1 and GaLV Env is primarily caused by the HIV-1 acce

Externí odkaz: https://doaj.org/article/95af594293b942f5b36c36854c0ad4da

Clathrin facilitates the morphogenesis of retrovirus particles.

Autor: Fengwen Zhang, Trinity Zang, Sam J Wilson, Marc C Johnson, Paul D Bieniasz

Publikováno v: PLoS Pathogens, Vol 7, Iss 6, p e1002119 (2011)

The morphogenesis of retroviral particles is driven by Gag and GagPol proteins that provide the major structural component and enzymatic activities required for particle assembly and maturation. In addition, a number of cellular proteins are found in

Externí odkaz: https://doaj.org/article/ed095b451e6f43c2b018662a5498dc39

Wastewater monitoring can anchor global disease surveillance systems

Autor: Aparna Keshaviah, Megan B Diamond, Matthew J Wade, Samuel V Scarpino, Warish Ahmed, Fabian Amman, Olusola Aruna, Andrei Badilla-Aguilar, Itay Bar-Or, Andreas Bergthaler, Julie E Bines, Aaron W Bivins, Alexandria B Boehm, Jean-Martin Brault, Jean-Baptiste Burnet, Joanne R Chapman, Angela Chaudhuri, Ana Maria de Roda Husman, Robert Delatolla, John J Dennehy, Megan Beth Diamond, Celeste Donato, Erwin Duizer, Abiodun Egwuenu, Oran Erster, Despo Fatta-Kassinos, Aldo Gaggero, Deirdre F Gilpin, Brent J Gilpin, Tyson E Graber, Christopher A Green, Amanda Handley, Joanne Hewitt, Rochelle H Holm, Heribert Insam, Marc C Johnson, Rabia Johnson, Davey L Jones, Timothy R Julian, Asha Jyothi, Tamar Kohn, Katrin G Kuhn, Giuseppina La Rosa, Marie Lesenfants, Douglas G Manuel, Patrick M D'Aoust, Rudolf Markt, John W McGrath, Gertjan Medema, Christine L Moe, Indah Kartika Murni, Humood Naser, Colleen C Naughton, Leslie Ogorzaly, Vicka Oktaria, Christoph Ort, Popi Karaolia, Ekta H Patel, Steve Paterson, Mahbubur Rahman, Pablo Rivera-Navarro, Alex Robinson, Monica C Santa-Maria, Heike Schmitt, Theodore Smith, Lauren B Stadler, Jorgen Stassijns, Alberta Stenico, Renee A Street, Elisabetta Suffredini, Zachary Susswein, Monica Trujillo, Marlene K Wolfe, Habib Yakubu, Maria Ines Zanoli Sato

Publikováno v: Keshaviah, A, Diamond, M B, Wade, M J, Scarpino, S V, Ahmed, W, Amman, F, Aruna, O, Badilla-Aguilar, A, Bar-Or, I, Bergthaler, A, Bines, J E, Bivins, A W, Boehm, A B, Brault, J-M, Burnet, J-B, Chapman, J R, Chaudhuri, A, de Roda Husman, A M, Delatolla, R, Dennehy, J J, Diamond, M B, Donato, C, Duizer, E, Egwuenu, A, Erster, O, Fatta-Kassinos, D, Gaggero, A, Gilpin, D F, Gilpin, B J, Graber, T E, Green, C A, Handley, A, Holm, R H, Insam, H, Johnson, M C, Johnson, R, Jones, D L, Julian, T R, Jyothi, A, Kohn, T, Kuhn, K G, La Rosa, G, Lesenfants, M, Manuel, D G, D'Aoust, P M, Markt, R, McGrath, J W, Medema, G, Moe, C L, Murni, I K, Naser, H, Naughton, C C, Ogorzaly, L, Oktaria, V, Ort, C, Karaolia, P, Patel, E H, Paterson, S, Rahman, M, Rivera-Navarro, P, Robinson, A, Santa-Maria, M C, Schmitt, H, Smith, T, Stadler, L B, Stassijns, J, Stenico, A, Street, R A, Suffredini, E, Susswein, Z, Trujillo, M, Wolfe, M K, Yakubu, H & Zanoli Sato, M I 2023, ' Wastewater monitoring can anchor global disease surveillance systems ', The Lancet Global Health, vol. 11, no. 6, pp. e976-e981 . https://doi.org/10.1016/S2214-109X(23)00170-5

To inform the development of global wastewater monitoring systems, we surveyed programmes in 43 countries. Most programmes monitored predominantly urban populations. In high-income countries (HICs), composite sampling at centralised treatment plants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cdcb7cd24a1ffe3de14b12692127c7
https://pure.qub.ac.uk/en/publications/25208d6c-5bd8-4b09-ad27-2286b2974293