Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marc Bossé"'
Autor:
Kausalia Vijayaragavan, Bryan J. Cannon, Dmitry Tebaykin, Marc Bossé, Alex Baranski, J. P. Oliveria, Syed A. Bukhari, Dunja Mrdjen, M. Ryan Corces, Erin F. McCaffrey, Noah F. Greenwald, Yari Sigal, Diana Marquez, Zumana Khair, Trevor Bruce, Mako Goldston, Anusha Bharadwaj, Kathleen S. Montine, R. Michael Angelo, Thomas J. Montine, Sean C. Bendall
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Neurodegenerative disorders are characterized by phenotypic changes and hallmark proteopathies. Quantifying these in archival human brain tissues remains indispensable for validating animal models and understanding disease mechanisms. We pre
Externí odkaz:
https://doaj.org/article/634355137dcd41ebab2eb6ab532fbf74
Autor:
Yunhao Bai, Bokai Zhu, John-Paul Oliveria, Bryan J. Cannon, Dorien Feyaerts, Marc Bosse, Kausalia Vijayaragavan, Noah F. Greenwald, Darci Phillips, Christian M. Schürch, Samuel M. Naik, Edward A. Ganio, Brice Gaudilliere, Scott J. Rodig, Michael B. Miller, Michael Angelo, Sean C. Bendall, Xavier Rovira-Clavé, Garry P. Nolan, Sizun Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Cellular organization and functions encompass multiple scales in vivo. Emerging high-plex imaging technologies are limited in resolving subcellular biomolecular features. Expansion Microscopy (ExM) and related techniques physically expand sa
Externí odkaz:
https://doaj.org/article/1aaa853ff55a4176b7b32d00970f18f6
Autor:
Marc Bosse
Mithilfe eines neutral-phänomenologischen Forschungsansatzes und eines von Wissensdefiziten losgelösten Professionalitätsbegriffs untersucht Marc Bosse fachfremd unterrichtende Mathematiklehrpersonen hinsichtlich ihrer mathematikbezogenen Erfahrun
Autor:
Eva Szabo, Mickie Bhatia, Kausalia Vijayaragavan, Randall T. Moon, Marc Bossé, Verónica Ramos-Mejía
Publikováno v:
Cell Stem Cell. 4(3):248-262
SummaryDuring human development, signals that govern lineage specification versus expansion of cells committed to a cell fate are poorly understood. We demonstrate that activation of canonical Wnt signaling by Wnt3a promotes proliferation of human em
Publikováno v:
Nature Methods. 3:807-815
Human embryonic stem cell (hESC) lines are known to be morphologically and phenotypically heterogeneous. The functional nature and relationship of cells residing within hESC cultures, however, has not been evaluated because isolation of single hESCs
Degradation of ubiquitinated proteins by 26 S proteasomes requires ATP hydrolysis, but it is unclear how the proteasomal ATPases are regulated and how proteolysis, substrate deubiquitination, degradation, and ATP hydrolysis are coordinated. Polyubiqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd561d9b46bab6357b747aa29936ce7
https://europepmc.org/articles/PMC3597817/
https://europepmc.org/articles/PMC3597817/
Publikováno v:
Journal of Immunological Methods. 165:253-261
As there is much heterogeneity in the morphology and function of blood eosinophils, comparison of their properties between groups of subjects requires recovering the majority of these cells. In two currently used techniques to isolate eosinophils, bl
Autor:
Mary-Jo Smith, Marc Bossé, Christopher Wynder, Angelique Schnerch, Timothy F. Carter, Tamra E. Werbowetski-Ogilvie, Charles Harris, Mickie Bhatia, Doug Boreham, Morag Stewart, Christopher Williams, Steve Dingwall, Jo-Anna Dolling, Verónica Ramos-Mejía, Anne Rouleau, Tracy Wynder
Publikováno v:
Nature biotechnology. 27(1)
Cultured human embryonic stem (hES) cells can acquire genetic and epigenetic changes that make them vulnerable to transformation. As hES cells with cancer-cell characteristics share properties with normal hES cells, such as self-renewal, teratoma for
Publikováno v:
Stem cells (Dayton, Ohio). 26(10)
The cellular mechanism and target cell affected by stromal microenvironments in augmenting hematopoietic specification from pluripotent human embryonic stem cells (hESCs) has yet to be evaluated. Here, in contrast to aorta-gonad-mesonephros-derived S
Autor:
Jiabi Yang, Kausalia Vijayaragavan, Morag Stewart, Marc Bossé, Tamra E. Werbowetski-Ogilvie, Sean C. Bendall, Anne Rouleau, Dustin George, Verónica Ramos-Mejía, Gilles A. Lajoie, Pablo Menendez, Mickie Bhatia
Publikováno v:
Nature. 448(7157)
Distinctive properties of stem cells are not autonomously achieved, and recent evidence points to a level of external control from the microenvironment. Here, we demonstrate that self-renewal and pluripotent properties of human embryonic stem (ES) ce