Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marc Boehning"'
Autor:
David Flores-Solis, Irina P. Lushpinskaia, Anton A. Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M. Pietrek, Patrick Cramer, Lukas S. Stelzl, Bojan Zagrovic, Markus Zweckstetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Eukaryotic gene regulation and pre-mRNA transcription depend on the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II. Due to its highly repetitive, intrinsically disordered sequence, the CTD enables clustering and phase separation of
Externí odkaz:
https://doaj.org/article/d764f11023754998bb583c1d63ee30b3
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Phosphatases, including phytases, play a major role in cell metabolism, phosphorus cycle, biotechnology, and pathogenic processes. Nevertheless, their discovery by functional metagenomics is challenging. Here, soil metagenomic libraries were
Externí odkaz:
https://doaj.org/article/825beb6ba15a4d78bc960b24f56bbfb5
Publikováno v:
Trends in cell biology. 30(1)
Liquid–liquid phase separation is a key organizational principle in eukaryotic cells, on par with intracellular membranes. It allows cells to concentrate specific proteins into condensates, increasing reaction rates and achieving switch-like regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56ff7c0e9698860a2cc2f1772733ecb
https://pubmed.ncbi.nlm.nih.gov/31753533
https://pubmed.ncbi.nlm.nih.gov/31753533
Liquid-liquid phase separation is a key organizational principle in eukaryotic cells, on par with intracellular membranes. It allows cells to concentrate specific proteins into condensates, increasing reaction rates and achieving switch-like regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55b940718b929280394f025f8eb4959
Autor:
Patrick Cramer, Lucas Farnung, Andreas Linden, Henning Urlaub, C. Wigge, Seychelle M. Vos, Marc Boehning
Publikováno v:
Nature
Gene regulation involves activation of RNA polymerase II (Pol II) that is paused and bound by the protein complexes DRB sensitivity-inducing factor (DSIF) and negative elongation factor (NELF). Here we show that formation of an activated Pol II elong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817e982059c56a0ac760aad2d4f72e3e
https://pubmed.ncbi.nlm.nih.gov/30143755
https://pubmed.ncbi.nlm.nih.gov/30143755
Autor:
Anders S. Hansen, Marc Boehning, Xavier Darzacq, Claire Dugast-Darzacq, Markus Zweckstetter, Marija Rankovic, Hervé Marie-Nelly, Taekyung Yu, Goran Kokic, David T. McSwiggen, Patrick Cramer, Gina M. Dailey
Publikováno v:
Nature structural & molecular biology 25(9), 833-840 (2018). doi:10.1038/s41594-018-0112-y
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology
The carboxy-terminal domain (CTD) of RNA polymerase (Pol) II is an intrinsically disordered low-complexity region that is critical for pre-mRNA transcription and processing. The CTD consists of hepta-amino acid repeats varying in number from 52 in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c978361045a062a49745de9c58b0dca
https://pub.dzne.de/record/140185
https://pub.dzne.de/record/140185