Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marc Benjamin Hahn"'
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-8 (2021)
Ionizing radiation damage to DNA plays a fundamental role in cancer therapy, whereby water radiolysis effects are important to take into account. Here, near-ambient-pressure X-ray photoelectron-spectroscopy is used to directly measure DNA damage duri
Externí odkaz:
https://doaj.org/article/feb980f9c5f44d5ba40f6b5600f47b79
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Dose enhancement by gold nanoparticles (AuNP) increases the biological effectiveness of radiation damage in biomolecules and tissue. To apply them effectively during cancer therapy their influence on the locally delivered dose has to be dete
Externí odkaz:
https://doaj.org/article/845087c4ff2344a4bae44ff5a1c6ffd0
Autor:
Marc Benjamin Hahn
Publikováno v:
Journal of Physics Communications, Vol 7, Iss 4, p 042001 (2023)
Radiation damage to DNA plays a central role in radiation therapy to cure cancer. The physico-chemical and biological processes involved encompass huge time and spatial scales. To obtain a comprehensive understanding on the nano and the macro scale i
Externí odkaz:
https://doaj.org/article/0ef4fcba93b64f0da35d325b9b59dabc
Publikováno v:
Physical Chemistry Chemical Physics. 25:5372-5382
Small-angle X-ray scattering (SAXS) is used for structural determination of biomolecules in liquids. To prevent radiation damage during bio-SAXS at single-stranded DNA-binding proteins the OH-radical scavenger and compatible solute Ectoine is used.
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 331:3033-3041
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-8 (2021)
Ionizing radiation damage to DNA plays a fundamental role in cancer therapy. X-ray photoelectron-spectroscopy (XPS) allows simultaneous irradiation and damage monitoring. Although water radiolysis is essential for radiation damage, all previous XPS s
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Dose enhancement by gold nanoparticles (AuNP) increases the biological effectiveness of radiation damage in biomolecules and tissue. To apply them effectively during cancer therapy their influence on the locally delivered dose has to be determined. H
Publikováno v:
Chemphyschem
Recent crystallographic results revealed conformational changes of zwitterionic ectoine upon hydration. By means of confocal Raman spectroscopy and density functional theory calculations, we present a detailed study of this transformation process as
Publikováno v:
Physical chemistry chemical physics : PCCP. 22(13)
Ectoine is a small zwitterionic osmolyte and compatible solute, which does not interfere with cell metabolism even at molar concentrations. Plasmid DNA (pUC19) was irradiated with ultraviolet radiation (UV-C at 266 nm) under quasi physiological condi
Autor:
Harald Seitz, Susann Meyer, Marc Benjamin Hahn, Maria-Astrid Schröter, Heinz Sturm, Hans-Jörg Kunte, Tihomir Solomun
Publikováno v:
Physical Chemistry Chemical Physics. 19:1798-1805
We report on a study in which plasmid DNA in water was irradiated with 30 keV electrons generated by a scanning electron microscope and passed through a 100 nm thick Si3N4 membrane. The corresponding Monte Carlo simulations suggest that the kinetic e