Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Marc B. Brown"'
Publikováno v:
Skin Health and Disease, Vol 3, Iss 3, Pp n/a-n/a (2023)
Abstract Background Topical corticosteroids (TCS) and emollients are developed independently by the pharmaceutical industry but are often used together in practice. There is potential for the TCS and emollient formulations to interact on the skin sur
Externí odkaz:
https://doaj.org/article/9c5df7c1317c45198f0bcec03d84da33
Autor:
Nicole L. van der Weerden, Kathy Parisi, James A. McKenna, Brigitte M. Hayes, Peta J. Harvey, Pedro Quimbar, Sean R. Wevrett, Prem K. Veneer, Owen McCorkelle, Shaily Vasa, Rosemary Guarino, Simon Poon, Yolanda M. Gaspar, Michael J. Baker, David J. Craik, Rob B. Turner, Marc B. Brown, Mark R. Bleackley, Marilyn A. Anderson
Publikováno v:
Journal of Fungi, Vol 9, Iss 11, p 1111 (2023)
Onychomycosis, or fungal nail infection, causes not only pain and discomfort but can also have psychological and social consequences for the patient. Treatment of onychomycosis is complicated by the location of the infection under the nail plate, mea
Externí odkaz:
https://doaj.org/article/17c6269b0f7a41c0908d35e989efa532
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-10 (2018)
Abstract Background “Residual skin surface components” (RSSC) is the collective term used for the superficial layer of sebum, residue of sweat, small quantities of intercellular lipids and components of natural moisturising factor present on the
Externí odkaz:
https://doaj.org/article/4f5a7c18a4e5407c822900aa64db5802
Autor:
Satyajit S. Shetage, Matthew J. Traynor, Marc B. Brown, Thomas M. Galliford, Robert P. Chilcott
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Metabolic imbalance in chronic diseases such as type-1 diabetes may lead to detectable perturbations in the molecular composition of residual skin surface components (RSSC). This study compared the accumulation rate and the composition of RS
Externí odkaz:
https://doaj.org/article/5f9ac5200aa147dbbc77e0e0813a81da
Autor:
Sean Robert Wevrett, John Farrah, Suzanne Edmunds, Oluwajoba Adegoke, Anuradha Kulasekaran, Marc B. Brown, Rob Turner
Publikováno v:
Clinical Pharmacology : Advances and Applications
Rob Turner,1 Sean Robert Wevrett,1 Suzanne Edmunds,1 Marc Brown,1 Anuradha Kulasekaran,2 Oluwajoba Adegoke,2 John Farrah2 1MedPharm Ltd, Guildford, UK; 2Reckitt Benckiser Healthcare International Ltd., Slough, Berkshire, UKCorrespondence: Oluwajoba A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fc17cf10dcc46178e88cd84ea8782c
https://doi.org/10.2147/cpaa.s284433
https://doi.org/10.2147/cpaa.s284433
Several in vitro models have been designed as test systems for inflammatory skin conditions, commonly using cell-culture or reconstructed human epidermis approaches. However, these systems poorly recapitulate the physiology and, importantly, the meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701490086edb5b4b65ec0c82568db40f
Publikováno v:
International journal of pharmaceutics. 618
Although animal models have been extensively used to evaluate human topical therapeutics, they exhibit marked physiological differences to human skin. Our objective was to develop a human ex vivo skin culture model to explore the pathophysiology of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9097b73002d5f4f8569a324a27e54d2f
https://pubmed.ncbi.nlm.nih.gov/35276230
https://pubmed.ncbi.nlm.nih.gov/35276230
Publikováno v:
Scientific Reports
The development of in vitro and ex vivo models to mimic human illness is important not only for scientific understanding and investigating therapeutic approaches but also to mitigate animal testing and bridge the inter-species translational gap. Whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be75b554ab79cdf60467349e6616de8c
https://doi.org/10.1038/s41598-020-78292-4
https://doi.org/10.1038/s41598-020-78292-4
Publikováno v:
Pharm Res
The aim of this work was to evaluate whether improved topical delivery of finasteride, focussed to the hair follicles of human scalp skin could be achieved with application of short durations of heat and use of specific chemical penetration enhancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44579b0518e82d129e8d0cdcae23e82
https://doi.org/10.1007/s11095-020-02862-4
https://doi.org/10.1007/s11095-020-02862-4
Publikováno v:
Pharmaceutical Research
Purpose The aim of this work was to evaluate whether improved topical delivery of finasteride, focussed to the hair follicles of human scalp skin could be achieved with application of short durations of heat and use of specific chemical penetration e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d8791d051d8d937614e99077b33ce0
https://doi.org/10.1007/s11095-020-02822-y
https://doi.org/10.1007/s11095-020-02822-y