Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marc A. Schwaller"'
Autor:
Yves Rolland, Marc A. Schwaller, Genevieve Chapuis, Guy Lewin, Jean-Marc Kühnel, Jacques Ferte
Publikováno v:
Journal of Medicinal Chemistry. 42:478-489
A series of 28 flavonoid derivatives containing a N-benzylpiperazine chain have been synthesized and tested for their ability to modulate multidrug resistance (MDR) in vitro. At 5 microM, most compounds potentiated doxorubicin cytotoxicity on resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbfe4111a5a025944373a1eb25fa3ef
https://doi.org/10.1021/jm981064b
https://doi.org/10.1021/jm981064b
Autor:
G. Alunni-Bistocchi, Marc A. Schwaller, Alfredo Ricci, B. Allard, P. L. Orvietani, M. Jouini, E. Lescot
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5908eb011e09b282973e9e3c22dea7ef
https://doi.org/10.1002/chin.199542233
https://doi.org/10.1002/chin.199542233
Autor:
Jean‐Marc Kuehnel, Marc A. Schwaller, Yves Rolland, Genevieve Chapuis, Jacques Ferte, Guy Lewin
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deafc7247769622744629a0e9467d4aa
https://doi.org/10.1002/chin.199923161
https://doi.org/10.1002/chin.199923161
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :839
Self-association mechanisms in aqueous media of ellipticinium (E), 2-methylellipticinium (2-NME), oxazolopyridocarbazolium (H-OPC), 10-pentyloxazolopyridocarbazolium (10-pentyl-OPC), 2 aminopentyloxazolopyridocarbazolium (2-aminopentyl-OPC) and 2-pen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71de15e6f954a63ecd6ab77f90ff6fc9
https://doi.org/10.1039/p29930000839
https://doi.org/10.1039/p29930000839
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :629-633
Ellipticine (E) seems to be included in two steps by two γ-cyclodextrin molecules. The first inclusion is detected by changes in the absorbance spectrum of ellipticine with added cyclodextrin. It occurs from the pyridine side of the molecule to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::538b3bc0b57abbb7f159b0f0d3f647ef
https://doi.org/10.1039/p29890000629
https://doi.org/10.1039/p29890000629
Publikováno v:
Journal of Molecular Recognition. 2:152-157
Using the fluorimetric determination of the binding isotherms in combination with circular dichroism, we have investigated the effect of the binding of the intercalating chromophore oxazolopyridocarbazole (OPC) to poly d(GMe5C) on B/Z equilibrium, co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fca01a30422f49eaf05be479e9d8e7
https://doi.org/10.1002/jmr.300020403
https://doi.org/10.1002/jmr.300020403
Publikováno v:
European journal of biochemistry. 181(1)
Among the DNA-intercalating drugs in the ellipticinium series, 9-hydroxy derivatives elicit the highest antitumoral properties. In water these drugs display a very low fluorescence quantum yield. Replacement of H2O by D2O partially restores the fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e960da2152297baa6da5f3d848fbb56
https://pubmed.ncbi.nlm.nih.gov/2714274
https://pubmed.ncbi.nlm.nih.gov/2714274
Publikováno v:
European journal of biochemistry. 176(2)
The acid-basic properties of ellipticine have been re-estimated. The apparent pK of protonation at 3 microM drug concentration is 7.4 +/- 0.1. The ellipticine free base (at pH 9, I = 25 mM) intercalates into calf-thymus DNA with an affinity constant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad090a6417ce68421b6de87c7da16318
https://pubmed.ncbi.nlm.nih.gov/2843372
https://pubmed.ncbi.nlm.nih.gov/2843372
Publikováno v:
European Journal of Biochemistry. 4/15/89, Vol. 181 Issue 1, p129-134. 6p.
Publikováno v:
European Journal of Biochemistry. 9/15/88, Vol. 176 Issue 2, p371-376. 6p.