Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marc A. Schureck"'
Autor:
Ankit Gupta, Praveen Balabaskaran-Nina, Wang Nguitragool, Gagandeep S. Saggu, Marc A. Schureck, Sanjay A. Desai
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Malaria parasites increase host erythrocyte permeability to ions and nutrients via a broad-selectivity channel known as the plasmodial surface anion channel (PSAC), linked to parasite-encoded CLAG3 and two associated proteins. These proteins
Externí odkaz:
https://doaj.org/article/bc49f608e99b45b6ae1ca729b4b9a946
Autor:
Ankit Gupta, Praveen Balabaskaran-Nina, Wang Nguitragool, Gagandeep S. Saggu, Marc A. Schureck, Sanjay A. Desai
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
Externí odkaz:
https://doaj.org/article/751e55f2923f4aab845a417c37a36adc
Autor:
Padmapriya Sekar, Sumati Rajagopalan, Estela Shabani, Usheer Kanjee, Marc A Schureck, Gunjan Arora, Mary E Peterson, Boubacar Traore, Peter D Crompton, Manoj T Duraisingh, Sanjay A Desai, Eric O Long
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011585 (2023)
Natural killer (NK) cells lyse virus-infected cells and transformed cells through polarized delivery of lytic effector molecules into target cells. We have shown that NK cells lyse Plasmodium falciparum-infected red blood cells (iRBC) via antibody-de
Externí odkaz:
https://doaj.org/article/aff072e252f94230992a43f271b45acd
Autor:
Marc A Schureck, Joseph E Darling, Alan Merk, Jinfeng Shao, Geervani Daggupati, Prakash Srinivasan, Paul Dominic B Olinares, Michael P Rout, Brian T Chait, Kurt Wollenberg, Sriram Subramaniam, Sanjay A Desai
Publikováno v:
eLife, Vol 10 (2021)
Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact and traffic through subcellular sites to serve these essential functions is
Externí odkaz:
https://doaj.org/article/da19fed0a9f244e489c10d2cf3ae9a97
Publikováno v:
eLife, Vol 6 (2017)
Malaria parasites evade immune detection by growth and replication within erythrocytes. After erythrocyte invasion, the intracellular pathogen must increase host cell uptake of nutrients from plasma. Here, we report that the parasite-encoded RhopH co
Externí odkaz:
https://doaj.org/article/ab53a0d863ae465c9fc83078c9735f20
Autor:
Joshua A. Ballard, Kevin Ebata, Hetal S. Randeria, Garrett Tinline, Thomas Lee, Lauren M. Hanson, John A. Latham, E. Peder Cedervall, Jenny Chong, Kyle B. Del Valle, Bernard C. Collins, Tony H. Morales, Thomas C. Benedict, Marc A. Schureck, Ethan T. Bender, Christopher Mendoza, David Molina, Meagan Nakamoto, Hsiao-Chiao Shiah, Hao Xu, Alfonso Espada, Leticia Cano, Charles K. Allerston, Paul Schnier, Barbara J. Brandhuber
Publikováno v:
Cancer Research. 83:2780-2780
Covalent Bruton tyrosine kinase inhibitors (cBTKi) have transformed the treatment of B cell malignancies. Despite the efficacy of cBTKi, treatment failure often occurs through development of resistance or intolerance. Pirtobrutinib, a highly selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf3f8c5886689c5d8629b41067488d7
https://doi.org/10.1158/1538-7445.am2023-2780
https://doi.org/10.1158/1538-7445.am2023-2780
Autor:
Dongxue Wang, Jeffrey Meisner, Shein Ei Cho, Christine M. Dunham, Nina Onuoha, Pete Lollar, Eric D. Hoffer, Marc A. Schureck
Publikováno v:
Mol Microbiol
Bacterial toxin-antitoxin systems are important factors implicated in growth inhibition and plasmid maintenance. Type II toxin-antitoxin pairs are regulated at the transcriptional level by the antitoxin itself. Here, we examined how the HigA antitoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199b8b6282e31b25297d754aa3dae3ab
https://doi.org/10.1111/mmi.14229
https://doi.org/10.1111/mmi.14229
Autor:
Stacey J. Miles, Eric D. Hoffer, Boamah M, Marc A. Schureck, Okafor Cd, Nina Onuoha, Dongxue Wang, Ian J Pavelich, Christine M. Dunham
Regulation of ubiquitous bacterial type II toxin-antitoxin (TA) gene pairs occurs via a negative feedback loop whereby their expression is typically responsive to changing levels of toxins at the transcriptional level similar to a molecular rheostat.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff18f2f0b750492cd9c8188a4ea858b
https://doi.org/10.1101/2021.03.04.434028
https://doi.org/10.1101/2021.03.04.434028
Autor:
Prakash Srinivasan, Paul Dominic B. Olinares, Joseph E Darling, Michael P. Rout, Marc A Schureck, Alan Merk, Kurt Wollenberg, Brian T. Chait, Sanjay A. Desai, Geervani Daggupati, Sriram Subramaniam, Jinfeng Shao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8c1aa86854422378c1a78f760a59df
https://doi.org/10.7554/elife.65282.sa2
https://doi.org/10.7554/elife.65282.sa2
Publikováno v:
Nucleic Acids Research
Bacteria encode multiple type II toxin–antitoxin modules that cleave ribosome-bound mRNAs in response to stress. All ribosome-dependent toxin family members structurally characterized to date adopt similar microbial RNase architectures despite poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ab77930ea0515452a25da50211836d
https://doi.org/10.1093/nar/gkw598
https://doi.org/10.1093/nar/gkw598