Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marc A. Moesser"'
Autor:
Johann S. de Bono, Adam Sharp, Stephen R. Plymate, Christopher J. Schofield, Bissan Al-Lazikani, Andrea Alimonti, Nina Tunariu, Suzanne Carreira, Maryou B. Lambros, Susana Miranda, Mateus Crespo, Lorenzo Buroni, Veronica S. Gil, Rossitza Christova, Bora Gurel, Akane Kawamura, Martine Abboud, Marc A. Moesser, Md. Saiful Islam, Anthony Tumber, Patrizio Di Micco, Takuma Uo, Soojin Kim, Juan M. Jiménez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Ana Ferreira, Rita Pereira, Ines Figueiredo, Wei Yuan, Antje J. Neeb, Jonathan Welti, Alec Paschalis
Supplementary Figure from JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc8fda216d27d81ffbe7ee2ca708e6
https://doi.org/10.1158/0008-5472.22427590.v1
https://doi.org/10.1158/0008-5472.22427590.v1
Autor:
Johann S. de Bono, Adam Sharp, Stephen R. Plymate, Christopher J. Schofield, Bissan Al-Lazikani, Andrea Alimonti, Nina Tunariu, Suzanne Carreira, Maryou B. Lambros, Susana Miranda, Mateus Crespo, Lorenzo Buroni, Veronica S. Gil, Rossitza Christova, Bora Gurel, Akane Kawamura, Martine Abboud, Marc A. Moesser, Md. Saiful Islam, Anthony Tumber, Patrizio Di Micco, Takuma Uo, Soojin Kim, Juan M. Jiménez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Ana Ferreira, Rita Pereira, Ines Figueiredo, Wei Yuan, Antje J. Neeb, Jonathan Welti, Alec Paschalis
Supplementary Table from JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbf18b25e3d8ff07736321b61556d50
https://doi.org/10.1158/0008-5472.22427587
https://doi.org/10.1158/0008-5472.22427587
Autor:
Johann S. de Bono, Adam Sharp, Stephen R. Plymate, Christopher J. Schofield, Bissan Al-Lazikani, Andrea Alimonti, Nina Tunariu, Suzanne Carreira, Maryou B. Lambros, Susana Miranda, Mateus Crespo, Lorenzo Buroni, Veronica S. Gil, Rossitza Christova, Bora Gurel, Akane Kawamura, Martine Abboud, Marc A. Moesser, Md. Saiful Islam, Anthony Tumber, Patrizio Di Micco, Takuma Uo, Soojin Kim, Juan M. Jiménez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Ana Ferreira, Rita Pereira, Ines Figueiredo, Wei Yuan, Antje J. Neeb, Jonathan Welti, Alec Paschalis
Endocrine resistance (EnR) in advanced prostate cancer is fatal. EnR can be mediated by androgen receptor (AR) splice variants, with AR splice variant 7 (AR-V7) arguably the most clinically important variant. In this study, we determined proteins key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8606cfe95f088ed08bde3c47fc7d4d73
https://doi.org/10.1158/0008-5472.c.6512749.v1
https://doi.org/10.1158/0008-5472.c.6512749.v1
Autor:
Andrew Baxter, Garrett Morris, Dominik Klein, Charlotte Deane, Marc Alexander Moesser, Fergus Boyles
Graph Neural Networks (GNNs) have recently gained in popularity, challenging molecular fingerprints or SMILES-based representations as the predominant way to represent molecules for binding affinity prediction. Although simple ligand-based graphs alo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9cd99fde07e7071de114c0e6813276
https://doi.org/10.1101/2022.03.04.483012
https://doi.org/10.1101/2022.03.04.483012
Autor:
Petra Lukacik, Victor Mikhailov, Tika R. Malla, Fernanda Duarte, Rebecca M. Twidale, Claire Strain-Damerell, Alessio Lodola, Deborah K. Shoemark, Vicent Moliner, Christopher J. Schofield, Martin A. Walsh, Helen M. Deeks, Luigi Genovese, Tobias John, Rebecca K. Walters, C. David Owen, David R. Glowacki, Garrett M. Morris, James Spencer, William Dawson, Marc A. Moesser, Adrian J. Mulholland, H. T. Henry Chan, Takahito Nakajima, Eidarus Salah, Tristan Johnston-Wood, Katarzyna Świderek, Richard B. Sessions
Publikováno v:
Chan, H T H, Moesser, M A, Walters, R K, Malla, T R, Twidale, R M, John, T, Deeks, H M, Johnston-Wood, T, Mikhailov, V, Sessions, R B, Dawson, W, Salah, E, Lukacik, P, Strain-Damerell, C, Owen, C D, Nakajima, T, Świderek, K, Lodola, A, Moliner, V, Glowacki, D R, Spencer, J, Walsh, M A, Schofield, C J, Genovese, L, Shoemark, D K, Mulholland, A J, Duarte, F & Morris, G M 2021, ' Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand binding ', Chemical Science, vol. 12, no. 41, pp. 13686-13703 . https://doi.org/10.1039/D1SC03628A, https://doi.org/10.1039/d1sc03628a
The main protease (Mpro) of SARS-CoV-2 is central to viral maturation and is a promising drug target, but little is known about structural aspects of how it binds to its 11 natural cleavage sites. We used biophysical and crystallographic data and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c512a698daef6740becef11c04e70c
https://research-information.bris.ac.uk/en/publications/49ca35cb-c19f-4d6d-bcab-d61edab231ca
https://research-information.bris.ac.uk/en/publications/49ca35cb-c19f-4d6d-bcab-d61edab231ca
Autor:
Eidarus Salah, Adrian J. Mulholland, Petra Lukacik, Rebecca M. Twidale, Takahito Nakajima, Vicent Moliner, David R. Glowacki, Katarzyna Swiderek, Luigi Genovese, Claire Strain-Damerell, David R. Owen, Tristan Johnston-Wood, Richard B. Sessions, H. T. Henry Chan, Martin A. Walsh, Victor A. Mikhailov, Rebecca K. Walters, Tika R. Malla, Fernanda Duarte, Helen M. Deeks, Garrett M. Morris, William Dawson, Christopher J. Schofield, Marc A. Moesser, Tobias John, Alessio Lodola, Deborah K. Shoemark
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Universitat Jaume I
The main protease (Mpro) of SARS-CoV-2 is central to its viral lifecycle and is a promising drug target, but little is known concerning structural aspects of how it binds to its 11 natural cleavage sites. We used biophysical and crystallographic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf8072372b994f2ab75956fda0782e4
Autor:
H T Henry, Chan, Marc A, Moesser, Rebecca K, Walters, Tika R, Malla, Rebecca M, Twidale, Tobias, John, Helen M, Deeks, Tristan, Johnston-Wood, Victor, Mikhailov, Richard B, Sessions, William, Dawson, Eidarus, Salah, Petra, Lukacik, Claire, Strain-Damerell, C David, Owen, Takahito, Nakajima, Katarzyna, Świderek, Alessio, Lodola, Vicent, Moliner, David R, Glowacki, James, Spencer, Martin A, Walsh, Christopher J, Schofield, Luigi, Genovese, Deborah K, Shoemark, Adrian J, Mulholland, Fernanda, Duarte, Garrett M, Morris
Publikováno v:
Chemical Science
The main protease (Mpro) of SARS-CoV-2 is central to viral maturation and is a promising drug target, but little is known about structural aspects of how it binds to its 11 natural cleavage sites. We used biophysical and crystallographic data and an
Autor:
Takuma Uo, Maryou B. Lambros, Suzanne Carreira, Ruth Riisnaes, Veronica Gil, Juan M. Jiménez-Vacas, Ana Ferreira, Susana Miranda, Andrea Alimonti, Jonathan Welti, Lorenzo Buroni, Mateus Crespo, Anthony Tumber, Daniel Nava Rodrigues, Marc A. Moesser, Alec Paschalis, Antje Neeb, Martine I. Abboud, Nina Tunariu, Patrizio Di Micco, Md. Saiful Islam, Akane Kawamura, Rossitza Christova, Wei Yuan, Bissan Al-Lazikani, Ines Figueiredo, Rita Pereira, Christopher J. Schofield, Stephen R. Plymate, Johann S. de Bono, Bora Gurel, Adam Sharp, Soojin Kim
Publikováno v:
Cancer Res
Endocrine resistance (EnR) in advanced prostate cancer is fatal. EnR can be mediated by androgen receptor (AR) splice variants, with AR splice variant 7 (AR-V7) arguably the most clinically important variant. In this study, we determined proteins key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbb4101eee9ccbabd94af29f3d9f9e6
http://hdl.handle.net/11577/3381996
http://hdl.handle.net/11577/3381996