Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Marc A. Ilies"'
Autor:
R. Kyle Palmer, Anna B. Nechiporenko, Marc A. Ilies, Marcel Winnig, Stephen A. Gravina, Rashmi Tiwari, Indra Prakash
Publikováno v:
PLoS ONE, Vol 19, Iss 11 (2024)
Externí odkaz:
https://doaj.org/article/4b6a86883e5343a687f9ec3f75105705
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The Neurovascular Unit (NVU) is an important multicellular structure of the central nervous system (CNS), which participates in the regulation of cerebral blood flow (CBF), delivery of oxygen and nutrients, immunological surveillance, clearance, barr
Externí odkaz:
https://doaj.org/article/2e237d06c34f4cc29217bc21e708cb15
Autor:
Eugen Brailoiu, Sumita Chakraborty, G. Cristina Brailoiu, Pingwei Zhao, Jeffrey L. Barr, Marc A. Ilies, Ellen M. Unterwald, Mary E. Abood, Colin W. Taylor
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 330-337.e4 (2019)
Summary: Sigma-1 receptors (Sig-1Rs) are integral ER membrane proteins. They bind diverse ligands, including psychoactive drugs, and regulate many signaling proteins, including the inositol 1,4,5-trisphosphate receptors (IP3Rs) that release Ca2+ from
Externí odkaz:
https://doaj.org/article/bba4f71ea52a4806843616fb0bce4be7
Autor:
Elisa Canepa, Rebecca Parodi-Rullan, Rafael Vazquez-Torres, Begona Gamallo-Lana, Roberto Guzman-Hernandez, Nicole L. Lemon, Federica Angiulli, Ludovic Debure, Marc A. Ilies, Leif Østergaard, Thomas Wisniewski, Eugenio Gutiérrez-Jiménez, Adam C. Mar, Silvia Fossati
Publikováno v:
Alzheimer's & Dementia.
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no effective cure. Cerebrovascular and neurovascular pathology are early and causal hallmarks of AD, where cerebral amyloid angiopathy (CAA), the deposition of amyloid β (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20080f4ca713c66fdd6ca9d00f13bcc
https://doi.org/10.1002/alz.13063
https://doi.org/10.1002/alz.13063
Autor:
Md. Abu Sufian, Sabina Zamanova, Ahmed M. Shabana, Brianna Kemp, Utpal K. Mondal, Claudiu T. Supuran, Marc A. Ilies
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4595
Volume 24
Issue 5
Pages: 4595
Carbonic anhydrase IX (CA IX) is a membrane-bound CA isozyme over-expressed in many hypoxic tumor cells, where it ensures pH homeostasis and has been implicated in tumor survival, metastasis and resistance to chemotherapy and radiotherapy. Given the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5b739ea9f2b8fcd078451011a5447f
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7acb624bb3275d8d1ecac419f200eff
https://doi.org/10.1002/alz.064845
https://doi.org/10.1002/alz.064845
Autor:
Md. Abu Sufian, Marc A. Ilies
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology. 15
Synthetic vectors for therapeutic nucleic acid delivery are currently competing significantly with their viral counter parts due to their reduced immunogenicity, large payload capacity, and ease of manufacture under GMP-compliant norms. The approval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb698afba83a17e5688575ed5a0ed872
https://doi.org/10.1002/wnan.1856
https://doi.org/10.1002/wnan.1856
Autor:
Shibbir Ahmed Khan, Marc A. Ilies
Publikováno v:
International Journal of Molecular Sciences. 24:1353
The phospholipase A2 (PLA2) superfamily of phospholipase enzymes hydrolyzes the ester bond at the sn-2 position of the phospholipids, generating a free fatty acid and a lysophospholipid. The PLA2s are amphiphilic in nature and work only at the water/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d9b7555c9c8ca263184e47bf66a2413
https://doi.org/10.3390/ijms24021353
https://doi.org/10.3390/ijms24021353
Autor:
Leslie Lam, Marc A. Ilies
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1262, p 1262 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1262
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1262
Esterases and lipases can process amphiphilic esters used as drugs and prodrugs and impact their pharmacokinetics and biodistribution. These hydrolases can also process ester components of drug delivery systems (DDSs), thus triggering DDSs destabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124341a00c5d720da61fcc6865f298b7
https://pubmed.ncbi.nlm.nih.gov/35163184
https://pubmed.ncbi.nlm.nih.gov/35163184
Autor:
Kazuo Sakurai, Marc A. Ilies
Publikováno v:
ACS Symposium Series. :ix-xiii
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14a348c508891644822269f76f96a28
https://doi.org/10.1021/bk-2019-1309.pr001
https://doi.org/10.1021/bk-2019-1309.pr001