Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marc A Harper"'
Autor:
Marc A Harper, Zugen Chen, Traci Toy, Iara M P Machado, Stanley F Nelson, James C Liao, Christopher J Lee
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16517 (2011)
Random mutagenesis and phenotype screening provide a powerful method for dissecting microbial functions, but their results can be laborious to analyze experimentally. Each mutant strain may contain 50-100 random mutations, necessitating extensive fun
Externí odkaz:
https://doaj.org/article/aaf6e814031f4c118da4a417748398bf
Autor:
Marc S. Harper, Raymond Layton, Waheed Pirzai, Bryan P. Hurley, Cindi Zimmermann, Bryan Delaney, Alex D. Eaton, Jason M. Roper, Gregory S. Ladics
Publikováno v:
Food and Chemical Toxicology. 92:75-87
Human intestinal epithelial cell lines (T84, Caco-2, and HCT-8) grown on permeable Transwell™ filters serve as models of the gastrointestinal barrier. In this study, this in vitro model system was evaluated for effectiveness at distinguishing betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ef789995188e74692d4698e24b0647
Autor:
Bryan Delaney, John F. Barnett, Ljubica Krsmanovic, Z. Amanda Shen, Marc S. Harper, Abby Myhre
Publikováno v:
Food and Chemical Toxicology. 47:2723-2729
N-acetyl-glutamic acid (NAG) is an endogenously produced mammalian substance and minor constituent of commonly consumed foods. This paper reports the outcome of genotoxicity and acute and repeated dose (28-day) oral toxicology studies conducted with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ac9a0c878ee74871c1867e8067cb40
https://doi.org/10.1016/j.fct.2009.07.036
https://doi.org/10.1016/j.fct.2009.07.036
Autor:
Mary E. Hartnett Locke, Ian C. Lamb, Joel L. Mattsson, Raymond Layton, Jean Schmidt, Lora Deege, Bryan Delaney, Michael J. Morrisey, Lee M. Prochaska, Marc S. Harper, Craig D. Sanders, Susan A. MacKenzie, Angel M. Fuentes
Publikováno v:
Food and Chemical Toxicology. 45:551-562
Maize line 1507, containing event DAS-Ø15Ø7-1 (1507), is a genetically modified (GM) maize plant that expresses the cry1F gene from Bacillus thuringiensis (Bt) sbsp. aizawai and the phosphinothricin-N-acetyltransferase (pat) gene from Streptomyces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433ca9418294a972fa0f6654f396c196
https://doi.org/10.1016/j.fct.2006.09.016
https://doi.org/10.1016/j.fct.2006.09.016
Autor:
Theodore L. Hopkins, Marc S. Harper
Publikováno v:
Archives of Insect Biochemistry and Physiology. 47:100-109
Peritrophic membrane (PM) structure and the effects of dietary wheat germ agglutinin (WGA) on PM formation were studied in larvae of the European corn borer (ECB), Ostrinia nubilalis, and the tobacco hornworm (THW), Manduca sexta. Growth of ECB was s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b9654a1883781f356f16dc821e2455
https://doi.org/10.1002/arch.1040
https://doi.org/10.1002/arch.1040
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 49(8)
A single dose of endotoxin (lipopolysaccharide) from a common laboratory cloning and expression strain ( Escherichia coli BL21[DE3]) was administered to groups of male and female CD-1 mice ( n = 5/group) at doses up to 1,000,000 endotoxin units (EU)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef797d1a33137b312a7221e7cec87cc
https://pubmed.ncbi.nlm.nih.gov/21554917
https://pubmed.ncbi.nlm.nih.gov/21554917
Autor:
Marc S. Harper, Laura Privalle, Dean F. Bushey, Bryan Delaney, Krishna M. Madduri, Rakesh Ranjan, John Zhang, Thomas C. Lee, Michael W. Pariza, Xiaoxu Jiang, Gerson Graser, Barry W. Schafer, Gloria Saab-Rincón, Jay J. Thelen, Mary Hefford, Gary A. Bannon
Publikováno v:
Regulatory Toxicology and Pharmacology. (2):154-170
Genetically modified (GM) crops may contain newly expressed proteins that are described as “intractable”. Safety assessment of these proteins may require some adaptations to the current assessment procedures. Intractable proteins are defined here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a815e7153de4b689d6d222b3546478