Výsledky vyhledávání - "Marc A, Daemen"

Elevated inflammatory cytokine expression in CSF from patients with symptomatic thoracic disc herniation correlates with increased pain scores

Autor: Marc A.R.C. Daemen, Erwin M. J. Cornips, Claudia Sommer, Govert Hoogland, Veerle Visser-Vandewalle, Pablo Andrade

Publikováno v: The Spine Journal, 18(12), 2316-2322. Elsevier Science

BACKGROUND: The pathophysiology of pain in patients with symptomatic thoracic disc herniation (TDH) remains poorly understood. Mere mechanical compression of the spinal cord and/or the exiting nerve root by a prolapsed disc cannot explain the pathoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464cb6dd2fca7b8bdf6347d916636356
https://doi.org/10.1016/j.spinee.2018.07.023

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Role of TNF-alpha during central sensitization in preclinical studies

Autor: Govert Hoogland, Veerle Visser-Vandewalle, Pablo Andrade, Harry W.M. Steinbusch, Carolin Hoffmann, Marc A.R.C. Daemen

Publikováno v: Neurological Sciences
Neurological Sciences, 32(5), 757-771. Springer

Tumor necrosis factor-alpha (TNF-alpha) is a principal mediator in pro-inflammatory processes that involve necrosis, apoptosis and proliferation. Experimental and clinical evidence demonstrate that peripheral nerve injury results in activation and mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d939d7d54bf5d3726694a04aa680f072
http://europepmc.org/articles/PMC3171667

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Protection of nigral cell death by bilateral subthalamic nucleus stimulation

Autor: Marc A.R.C. Daemen, Süleyman Kaplan, Yasin Temel, Christoph Schmitz, Ramazan Kozan, Harry W.M. Steinbusch, Veerle Visser-Vandewalle, Arjan Blokland

Publikováno v: Brain Research, 1120(1), 100-105. Elsevier

Kaplan, Suleyman/0000-0003-1477-5002 WOS: 000242232200011 PubMed: 16999940 In Parkinson disease (PD), the subthalamic nucleus (STN) becomes hyperactive (disinhibited), which is reported to cause excitotoxic damage to midbrain dopaminergic neurons. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b017edee5df8b79775ecb1e07703d2
https://cris.maastrichtuniversity.nl/en/publications/05d0fc65-1860-4c7c-befd-fa0db5d44715

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Tumor necrosis factor-α inhibitors alleviation of experimentally induced neuropathic pain is associated with modulation of TNF receptor expression

Autor: Pablo, Andrade, Govert, Hoogland, John S, Del Rosario, Harry W, Steinbusch, Veerle, Visser-Vandewalle, Marc A, Daemen

Publikováno v: Journal of neuroscience research. 92(11)

Inflammation plays a key role in the development of sensitization after peripheral nerve damage. We recently demonstrated that tumor necrosis factor-α receptor (TNFR) levels in the spinal cord correlate with pain sensation in herniated disc patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94ce157ca0c0dbf00078f4fbe1338e63
https://pubmed.ncbi.nlm.nih.gov/24964368

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