Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Marc, de Perrot"'
Autor:
Marie Bambrick, MBBChBAO, FFRRCSI, Grace Grafham, MSc, Katherine Lajkosz, MSc, Laura Donahoe, MD, MSc, FRCSC, Marc de Perrot, MD, MSc, FRCSC, Micheal McInnis, MD, FRCPC
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100130- (2024)
Background: Registry data suggest women are less likely than men to undergo pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension despite a similar proportion of proximal vs distal disease. We hypothesized that sex-specifi
Externí odkaz:
https://doaj.org/article/623785a19a1743cb87151687ba668429
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/621a3e9882054232b575d602e77cb5d5
Autor:
H. S. Jeffrey Man, Vaneeza A. Moosa, Anand Singh, Licun Wu, John T. Granton, Stephen C. Juvet, Chuong D. Hoang, Marc de Perrot
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Awareness of RNA-based therapies has increased after the widespread adoption of mRNA vaccines against SARS-CoV-2 during the COVID-19 pandemic. These mRNA vaccines had a significant impact on reducing lung disease and mortality. They highlighted the p
Externí odkaz:
https://doaj.org/article/28306af162c14f71b1c0bc7bbe5537cf
Autor:
Grace K. Grafham, Marie Bambrick, Christian Houbois, Sebastian Mafeld, Laura Donahoe, Marc de Perrot, Micheal C. McInnis
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e20899- (2023)
Background: Surgical risk in chronic thromboembolic pulmonary hypertension (CTEPH) depends on the proximity of thromboembolism on CT pulmonary angiography (CTPA). We assessed interobserver agreement for the quantification of thromboembolic lesions in
Externí odkaz:
https://doaj.org/article/b771d7cdbe8745ddbfbb82f658ad45dd
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Chronic thromboembolic pulmonary hypertension (CTEPH) is a challenging diagnosis that can occur even in the absence of a prior thrombotic event. The main screening test is ventilation-perfusion (VQ) scintigraphy. The gold standard treatment for CTEPH
Externí odkaz:
https://doaj.org/article/099404203ea04e3dbcfc59bade7cabaa
Autor:
Caroline Rodrigues, Hagit Peretz Soroka, Agostino Pierro, Reto M. Baertschiger, Marcelo Cypel, Laura Donahoe, Derek S. Tsang, John Cho, Marc De Perrot, Thomas K. Waddell, Abha A. Gupta
Publikováno v:
Current Oncology, Vol 29, Iss 6, Pp 4260-4266 (2022)
Sarcoma can present as locally advanced disease involving pleura for which extra-pleural pneumonectomy (EPP) may be the only surgical option to ensure adequate local control. Data were collected on patients who underwent EPP between January 2009 and
Externí odkaz:
https://doaj.org/article/e3579c6f3a4745729b4e7ef227167545
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Malignant mesothelioma (MESO) is a highly aggressive cancer with poor prognosis. Epithelial–mesenchymal transition (EMT) is a critical process in malignancies involved in tumor angiogenesis, progression, invasion and metastasis, immunosupp
Externí odkaz:
https://doaj.org/article/843b940267f047e8b4b361c24084f0d5
Autor:
Licun Wu, Marc de Perrot
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1103 (2023)
The SPARC gene plays multiple roles in extracellular matrix synthesis and cell shaping, associated with tumor cell migration, invasion, and metastasis. The SPARC gene is also involved in the epithelial-mesenchymal transition (EMT) process, which is a
Externí odkaz:
https://doaj.org/article/f08987965c584631b90b61b95f5550f3
Autor:
Meilin Chan, Licun Wu, Zhihong Yun, Trevor D. McKee, Michael Cabanero, Yidan Zhao, Mikihiro Kohno, Junichi Murakami, Marc de Perrot
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Chan et al find that the GITR-GITRL pathway is an important mechanism of autocrine proliferation in sarcomatoid mesothelioma that could explain their resistance to therapy. Blocking the GITR-GITRL pathway could therefore be a new therapeutic target f
Externí odkaz:
https://doaj.org/article/3c5ca878a66742d7a38438d115052146
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Carbon nanotubes (CNTs) are nanomaterials with broad applications that are produced on a large scale. Animal experiments have shown that exposure to CNTs, especially one type of multi-walled carbon nanotube, MWCNT-7, can lead to malignant transformat
Externí odkaz:
https://doaj.org/article/6918a5b413a54382928ee475606a69ec