Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marc, Van der Kamp"'
Autor:
Andrew Poole, Vijaykumar Karuppiah, Annabelle Hartt, Jaafar N. Haidar, Sylvie Moureau, Tomasz Dobrzycki, Conor Hayes, Christopher Rowley, Jorge Dias, Stephen Harper, Keir Barnbrook, Miriam Hock, Charlotte Coles, Wei Yang, Milos Aleksic, Aimee Bence Lin, Ross Robinson, Joe D. Dukes, Nathaniel Liddy, Marc Van der Kamp, Gregory D. Plowman, Annelise Vuidepot, David K. Cole, Andrew D. Whale, Chandramouli Chillakuri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cancers often harbor mutations in genes encoding important regulatory proteins, but therapeutic targeting of these molecules proves difficult due to their high structural similarity to their non-mutated counterpart. Here authors show the engineering
Externí odkaz:
https://doaj.org/article/d2f84672e7fe4eb3b7df368784cf9d36
Autor:
David Cole, Annelise Vuidepot, Andrew Whale, Andrew Poole, Vijaykumar Karuppiah, Annabelle Hartt, Jaafar Haidar, Sylvie Moureau, Aimee Bence Lin, Marc Van der Kamp, Gregory Plowman, Chandramouli Chillakuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/f88c19af0c8e4b699fedf005b648101c
Autor:
Helen Deeks, Kirill Zinovjev, Jonathan Barnoud, Adrian Mulholland, Marc van der Kamp, David Glowacki
iMD-VR trajectories, narupa inputs, system parameters, and umbrella sampling data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c689c6ce76eedcbcfa85ca488c7391ea
Autor:
Helen Deeks, Kirill Zinovjev, Jonathan Barnoud, Adrian Mulholland, Marc van der Kamp, David Glowacki
We describe a novel two-step approach for combining cloud-mounted interactive molecular dynamics in virtual reality (iMD-VR) with free energy sampling (FES) approaches to quantitatively explore the dynamics of biological processes at the molecular le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9350aeac003324a26395f1a78386e24
https://doi.org/10.26434/chemrxiv-2022-w89tc
https://doi.org/10.26434/chemrxiv-2022-w89tc
OXA-48 β-lactamases are frequently encountered in bacterial infections caused by carbapenem-resistant Gram-negative bacteria. Due to the importance of carbapenems in treatment of healthcare-associated infections, and the increasingly wide disseminat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d87075f4047f227d4bdb6dd3ecbf30
https://doi.org/10.26434/chemrxiv-2021-bv7tb-v2
https://doi.org/10.26434/chemrxiv-2021-bv7tb-v2
Autor:
Andrew, Poole, Vijaykumar, Karuppiah, Annabelle, Hartt, Jaafar N, Haidar, Sylvie, Moureau, Tomasz, Dobrzycki, Conor, Hayes, Christopher, Rowley, Jorge, Dias, Stephen, Harper, Keir, Barnbrook, Miriam, Hock, Charlotte, Coles, Wei, Yang, Milos, Aleksic, Aimee Bence, Lin, Ross, Robinson, Joe D, Dukes, Nathaniel, Liddy, Marc, Van der Kamp, Gregory D, Plowman, Annelise, Vuidepot, David K, Cole, Andrew D, Whale, Chandramouli, Chillakuri
Publikováno v:
Nature communications. 13(1)
Neoantigens derived from somatic mutations are specific to cancer cells and are ideal targets for cancer immunotherapy. KRAS is the most frequently mutated oncogene and drives the pathogenesis of several cancers. Here we show the identification and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09b6f49fe5f2b3f9dd982b4e6d4e47e8
https://pubmed.ncbi.nlm.nih.gov/36088370
https://pubmed.ncbi.nlm.nih.gov/36088370
Autor:
Marc Van der Kamp, Kirill Zinovjev
Motivation: Experimental structural data can allow detailed insight into protein structure and protein-ligand interactions, which is crucial for many areas of bioscience, including drug design and enzyme engineering. Typically, however, little more t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::014d02cae53994f5451651603f1b63ff
https://doi.org/10.26434/chemrxiv.11881542.v2
https://doi.org/10.26434/chemrxiv.11881542.v2
Autor:
Alejandro Rodríguez, Carolina Oliva, Miguel González, Marc van der Kamp, Adrian J. Mulholland
Publikováno v:
Journal of Physical Chemistry B; Nov2007, Vol. 111 Issue 44, p12909-12915, 7p