Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Marc, Romana"'
Autor:
Emmanuelle Bernit, Marc Romana, Scylia Alexis‐Fardini, Vanessa Tarer, Pierre‐Marie Roger, Lydia Doumdo, Eléonore Petras, Corine Charneau, Benoit Tressières, Marie Dominique Hardy Dessources, Maryse Etienne‐Julan
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 636-643 (2022)
Abstract We investigate risk factors for hospitalization and difference between sickle cell syndromes in a cohort of COVID‐19 sickle cell disease (SCD) adult patients managed in the Reference Center of Guadeloupe. We retrospectively collected data
Externí odkaz:
https://doaj.org/article/a9f653fe2bb84bb78310f709381bd744
Autor:
Sofia Esperti, Elie Nader, Antoine Stier, Camille Boisson, Romain Carin, Muriel Marano, Mélanie Robert, Marie Martin, Françoise Horand, Agnes Cibiel, Céline Renoux, Robin Van Bruggen, Colin Blans, Yesim Dargaud, Philippe Joly, Alexandra Gauthier, Solène Poutrel, Marc Romana, Damien Roussel, Philippe Connes
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Abnormal retention of mitochondria in mature red blood cells (RBC) has been recently reported in sickle cell anemia (SCA) but their functionality and their role in the pathophysiology of SCA remain unknown. The presence of mitochondria within RBC was
Externí odkaz:
https://doaj.org/article/384030a7517d42a8b9b05613491174cd
Autor:
Amélie Rollé, Elsa Vidal, Pierre Laguette, Yohann Garnier, Delphine Delta, Frédéric Martino, Patrick Portecop, Maryse Etienne-Julan, Pascale Piednoir, Audrey De Jong, Marc Romana, Emmanuelle Bernit
Publikováno v:
Medicina, Vol 59, Iss 12, p 2196 (2023)
Background and Objectives: Pain management poses a significant challenge for patients experiencing vaso-occlusive crisis (VOC) in sickle cell disease (SCD). While opioid therapy is highly effective, its efficacy can be impeded by undesirable side eff
Externí odkaz:
https://doaj.org/article/4f9f95f8b17d4eafa3cb48aee199a8c0
Autor:
Daniel A. Bizjak, Fabian Tomschi, Gunnar Bales, Elie Nader, Marc Romana, Philippe Connes, Wilhelm Bloch, Marijke Grau
Publikováno v:
Journal of Sport and Health Science, Vol 9, Iss 6, Pp 595-603 (2020)
Objective: To examine the impact of a 6-week endurance training on red blood cell (RBC) aging and deformability of healthy participants to detect possible improved hemorheological and performance-related adaptations. Methods: A total of 31 participan
Externí odkaz:
https://doaj.org/article/62c784fd6b614f17a4582a31e3691e47
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Prototype of monogenic disorder, sickle cell disease (SCD) is caused by a unique single mutation in the β-globin gene, leading to the production of the abnormal hemoglobin S (HbS). HbS polymerization in deoxygenated condition induces the sickling of
Externí odkaz:
https://doaj.org/article/b6aeba5668834c84b56ac26589b26c3c
Publikováno v:
Bioengineering, Vol 9, Iss 9, p 439 (2022)
Sickle cell disease (SCD) is the most common hemoglobinopathy worldwide. It is characterized by an impairment of shear stress-mediated vasodilation, a pro-coagulant, and a pro-adhesive state orchestrated among others by the depletion of the vasodilat
Externí odkaz:
https://doaj.org/article/3bed7c3dfda34698b33f03f6601bb963
Autor:
David-Zacharie Issom, Marie-Dominique Hardy-Dessources, Marc Romana, Gunnar Hartvigsen, Christian Lovis
Publikováno v:
Frontiers in Digital Health, Vol 3 (2021)
Sickle cell disease (SCD) is the most common genetic blood disorder in the world and affects millions of people. With aging, patients encounter an increasing number of comorbidities that can be acute, chronic, and potentially lethal (e.g., pain, mult
Externí odkaz:
https://doaj.org/article/babe8ea144d9495ea290ccb755069498
Autor:
Elie Nader, Marc Romana, Nicolas Guillot, Romain Fort, Emeric Stauffer, Nathalie Lemonne, Yohann Garnier, Sarah Chambers Skinner, Maryse Etienne-Julan, Mélanie Robert, Alexandra Gauthier, Giovanna Cannas, Sophie Antoine-Jonville, Benoît Tressières, Marie-Dominique Hardy-Dessources, Yves Bertrand, Cyril Martin, Céline Renoux, Philippe Joly, Marijke Grau, Philippe Connes
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO are known to modulate eryptosis in healthy red blood cells (RBCs); however, their
Externí odkaz:
https://doaj.org/article/327d7cbdbea248aeb284d431ff770a87
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Sickle cell disease (SCD) is a genetic disease caused by a single mutation in the β-globin gene, leading to the production of an abnormal hemoglobin called hemoglobin S (HbS), which polymerizes under deoxygenation, and induces the sickling of red bl
Externí odkaz:
https://doaj.org/article/1b1c8e1624cd45cc9796836b4d163989
Autor:
Marie-Laure Lalanne-Mistrih, Philippe Connes, Yann Lamarre, Nathalie Lemonne, Marie-Dominique Hardy-Dessources, Vanessa Tarer, Maryse Etienne-Julan, Dominique Mougenel, Benoît Tressières, Marc Romana
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background The pathophysiology of sickle cell disease (SCD) and the variability of its clinical expression remain not fully understood, whether within or between different SCD genotypes. Recent studies have reported associations between lipi
Externí odkaz:
https://doaj.org/article/93c0d9a1e3724710a6fa3e8cb2a9159b