Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Marc, Ferrer"'
Autor:
Isabel Schnorr, Anne Siegl, Sonja Luckhardt, Söri Wenz, Hendrik Friedrichsen, Hiba El Jomaa, Annebirth Steinmann, Tünde Kilencz, Gara Arteaga-Henríquez, Carolina Ramos-Sayalero, Pol Ibanez-Jimenez, Silvia Karina Rosales-Ortiz, István Bitter, Christian Fadeuilhe, Marc Ferrer, Catharina Lavebratt, János M. Réthelyi, Vanesa Richarte, Nanda Rommelse, Josep Antoni Ramos-Quiroga, Alejandro Arias-Vasquez, Eduard Resch, Andreas Reif, Silke Matura, Carmen Schiweck
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The association between Attention Deficit Hyperactivity Disorder (ADHD) and low-grade inflammation has been explored in children but rarely in adults. Inflammation is characteristic of some, but not all, patients with ADHD and might be influ
Externí odkaz:
https://doaj.org/article/4bc89e4d3415447fabfce8ba414f41d5
Autor:
América Chandía-Cristi, Daniela A. Gutiérrez, Andrés E. Dulcey, Marcelo Lara, Lina Vargas, Yi-Han Lin, Pablo Jimenez-Muñoz, Gabriela Larenas, Xin Xu, Amy Wang, Ashley Owens, Christopher Dextras, YuChi Chen, Claudio Pinto, Tamara Marín, Hugo Almarza-Salazar, Keryma Acevedo, Gonzalo I. Cancino, Xin Hu, Patricio Rojas, Marc Ferrer, Noel Southall, Mark J. Henderson, Silvana Zanlungo, Juan J. Marugan, Alejandra Álvarez R
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114144- (2024)
Summary: The molecular mechanisms underlying seizure generation remain elusive, yet they are crucial for developing effective treatments for epilepsy. The current study shows that inhibiting c-Abl tyrosine kinase prevents apoptosis, reduces dendritic
Externí odkaz:
https://doaj.org/article/d6f3af7f5f984ae686e586e3fd0a0393
Autor:
Caroline E. Strong, Jiajing Zhang, Martin Carrasco, Srikanya Kundu, Molly Boutin, Harshad D. Vishwasrao, Jiamin Liu, Angelica Medina, Yu-Chi Chen, Kelli Wilson, Emily M. Lee, Marc Ferrer
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract 3D spheroids have emerged as powerful drug discovery tools given their high-throughput screening (HTS) compatibility. Here, we describe a method for generating functional neural spheroids by cell-aggregation of differentiated human induced p
Externí odkaz:
https://doaj.org/article/f3586b8c452a49948ce8a41970b8c9ec
Autor:
Natalia Calvo, Jorge Lugo Marin, Raquel Vidal, Carla Sharp, Juan D. Duque, Josep-Antoni Ramos-Quiroga, Marc Ferrer
Publikováno v:
Borderline Personality Disorder and Emotion Dysregulation, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Background Although the diagnosis of Borderline Personality Disorder (BPD) during adolescence has been questioned, many recent studies have confirmed its validity. However, some clinical manifestations of BPD could be identifiable in adolesc
Externí odkaz:
https://doaj.org/article/9f1d1cbf8f6e402c80c9ab6cd2868a61
Autor:
Martin Lang, Laura S. Schmidt, Kelli M. Wilson, Christopher J. Ricketts, Carole Sourbier, Cathy D. Vocke, Darmood Wei, Daniel R. Crooks, Youfeng Yang, Benjamin K. Gibbs, Xiaohu Zhang, Carleen Klumpp-Thomas, Lu Chen, Rajarshi Guha, Marc Ferrer, Crystal McKnight, Zina Itkin, Darawalee Wangsa, Danny Wangsa, Amy James, Simone Difilippantonio, Baktir Karim, Francisco Morís, Thomas Ried, Maria J. Merino, Ramaprasad Srinivasan, Craig J. Thomas, W. Marston Linehan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background MiT-Renal Cell Carcinoma (RCC) is characterized by genomic translocations involving microphthalmia-associated transcription factor (MiT) family members TFE3, TFEB, or MITF. MiT-RCC represents a specific subtype of sporadic RCC tha
Externí odkaz:
https://doaj.org/article/6b0458681f774fc788c19d8f3ed9c6d2
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-19 (2022)
Fibrin gel-based 3D co-culture models with human-iPSC differentiated dopaminergic or glutamatergic neurons and astrocytes are shown to be functional using biosensors and can be scaled up for high-throughput assays.
Externí odkaz:
https://doaj.org/article/702753a546e946b59524558bd3ae3339
Autor:
Maria Esteban-Lopez, Kenneth J. Wilson, Courtney Myhr, Elena M. Kaftanovskaya, Mark J. Henderson, Noel T. Southall, Xin Xu, Amy Wang, Xin Hu, Elena Barnaeva, Wenjuan Ye, Emmett R. George, John T. Sherrill, Marc Ferrer, Roy Morello, Irina U. Agoulnik, Juan J. Marugan, Alexander I. Agoulnik
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Specific small molecule RXFP2 agonists with favorable pharmacokinetic properties induce gubernacular invagination in mouse embryos, increase mineralization activity in human osteoblasts in vitro, and improve bone trabecular parameters in adult mice.
Externí odkaz:
https://doaj.org/article/50c86baebeb04e3ebabf87beea0be0a0
Autor:
Samar Sayedyahossein, Jessica Smith, Elena Barnaeva, Zhigang Li, Jun Choe, Michael Ronzetti, Christopher Dextras, Xin Hu, Juan Marugan, Noel Southall, Bolormaa Baljinnyam, Louise Thines, Andy D. Tran, Marc Ferrer, David B. Sacks
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The small GTPase Cdc42 is an integral component of the cytoskeleton, and its dysregulation leads to pathophysiological conditions, such as cancer. Binding of Cdc42 to the scaffold protein IQGAP1 stabilizes Cdc42 in its active form. The inter
Externí odkaz:
https://doaj.org/article/1a21390492ac417fa1c9c755b05598aa
Autor:
Marc Ferrer
Publikováno v:
Revista de Humanidades Digitales, Vol 8 (2023)
En este artículo detallaremos los principios teóricos y procedimentales para realizar un análisis de clústeres aplicado a los estudios históricos medievales utilizando el método de la distancia de Gower. Los análisis de clústeres son una herr
Externí odkaz:
https://doaj.org/article/b89f55f803f24db69b3a04910a01e76f
Autor:
Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova, Olive Jung, Steven Coon, Min Jae Song, Jun-Gyu Park, Fatai Oladunni, Jesse Miller, Yen-Ting Tung, Ivan Kosik, David Schultz, James Iben, Tianwei Li, Jiaqi Fu, Forbes D. Porter, Jonathan Yewdell, Luis Martinez-Sobrido, Sara Cherry, Jordi B. Torrelles, Marc Ferrer, Emily M. Lee
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms.
Externí odkaz:
https://doaj.org/article/003ca60ed064430890c5954d0c4a6343