Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marc, Evanchik"'
Autor:
Man-Fung Yuen, Kosh Agarwal, Xiaoli Ma, Tuan T. Nguyen, Eugene R. Schiff, Hie-Won L. Hann, Douglas T. Dieterich, Ronald G. Nahass, James S. Park, Sing Chan, Steven-Huy B. Han, Edward J. Gane, Michael Bennett, Katia Alves, Marc Evanchik, Ran Yan, Qi Huang, Uri Lopatin, Richard Colonno, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Ira M. Jacobson, Walid S. Ayoub, Frank Weilert, Natarajan Ravendhran, Alnoor Ramji, Paul Yien Kwo, Magdy Elkhashab, Tarek Hassanein, Ho S. Bae, Jacob P. Lalezari, Scott K. Fung, Mark S. Sulkowski
Publikováno v:
Journal of Hepatology. 77:642-652
HBV nucleos(t)ide reverse transcriptase inhibitors (NrtIs) do not completely suppress HBV replication. Previous reports indicate persistent viremia during NrtI treatment despite HBV DNA being undetectable. HBV core inhibitors may enhance viral suppre
Autor:
Kosh Agarwal, Jia Xu, Edward J. Gane, Tuan T. Nguyen, Yanhua Ding, Steven J. Knox, Katia Alves, Marc Evanchik, Katie Zomorodi, Julie Ma, Ran Yan, Qi Huang, Richard Colonno, Luisa M. Stamm, Tarek I. Hassanein, Dong Joon Kim, Young‐Suk Lim, Man‐Fung Yuen
Publikováno v:
Journal of viral hepatitis.
Treatment for chronic hepatitis B virus infection (cHBV) is mostly indefinite, with new finite-duration therapies needed. We report safety, pharmacokinetics, and antiviral activity of the investigational HBV core inhibitor ABI-H2158. This Phase 1a/b
Autor:
Mark P. Grillo, Svetlana Markova, Marc Evanchik, Marc Trellu, Patricia Moliner, Priscilla Brun, Anne Perreard-Dumaine, Pascale Vicat, Chun Yang, James P. Driscoll, Tim J. Carlson
Publikováno v:
Xenobiotica. 51:222-238
Dilated cardiomyopathy (DCM) is a disease of the myocardium defined by left ventricular enlargement and systolic dysfunction leading to heart failure. Danicamtiv, a new targeted myosin activator de...
Autor:
Joanna Kaplan, Sarah Lehman, Mike Duvall, Molly Madden, Jessica Tolley, Natalie Hawryluk, Stephen Schlachter, Victor Rivas, Carina Jauregui, Amanda Crofton, Samantha Harris, Joshua Aaron Stern, Carlos L. del Rio, Alan Russell, Marc Evanchik
Publikováno v:
Journal of the American College of Cardiology. 81:349
Autor:
Mark S. Sulkowski, Kosh Agarwal, Xiaoli Ma, Tuan T. Nguyen, Eugene R. Schiff, Hie-Won L. Hann, Douglas T. Dieterich, Ronald G. Nahass, James S. Park, Sing Chan, Steven-Huy B. Han, Edward J. Gane, Michael Bennett, Katia Alves, Marc Evanchik, Ran Yan, Qi Huang, Uri Lopatin, Richard Colonno, Julie Ma, Steven J. Knox, Luisa M. Stamm, Maurizio Bonacini, Ira M. Jacobson, Walid S. Ayoub, Frank Weilert, Natarajan Ravendhran, Alnoor Ramji, Paul Yien Kwo, Magdy Elkhashab, Tarek Hassanein, Ho S. Bae, Jacob P. Lalezari, Scott K. Fung, Man-Fung Yuen
Publikováno v:
Journal of hepatology. 77(5)
Nucleos(t)ide reverse transcriptase inhibitors do not completely suppress HBV DNA in chronic HBV infection (cHBV). Vebicorvir (VBR) is an investigational core inhibitor that interferes with multiple aspects of HBV replication. This phase II trial eva
Autor:
Breanne Stamper, Sarah Lehman, Molly Madden, Mike DuVall, Ying Qian, Marc Evanchik, Ben Barthel, Carlos L. del Rio, Alan J. Russell
Publikováno v:
Biophysical Journal. 121:515a-516a
Autor:
Mark P, Grillo, Svetlana, Markova, Marc, Evanchik, Marc, Trellu, Patricia, Moliner, Priscilla, Brun, Anne, Perreard-Dumaine, Pascale, Vicat, James P, Driscoll, Tim J, Carlson
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 51(2)
Dilated cardiomyopathy (DCM) is a disease of the myocardium defined by left ventricular enlargement and systolic dysfunction leading to heart failure. Danicamtiv, a new targeted myosin activator designed for the treatment of DCM, was characterised in