Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Marc, Borsotto"'
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/329e75f18c8a4132a6e6a15628350d6a
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
TREK-1 is the most studied background K2P channel. Its main role is to control cell excitability and maintain the membrane potential below the threshold of depolarization. TREK-1 is multi-regulated by a variety of physical and chemical stimuli which
Externí odkaz:
https://doaj.org/article/8f58c11c8f8b43acae9e578307e3026b
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
The molecular identification of sortilin, also called neurotensin receptor-3, from three different biochemical approaches already predicted the involvement of the protein in numerous biological and cellular functions. The first important observation
Externí odkaz:
https://doaj.org/article/34628f01de0744428f6e5d1e0e24609d
Autor:
Sébastien Moreno, Christelle M. Devader, Mariel Pietri, Marc Borsotto, Catherine Heurteaux, Jean Mazella
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The background potassium channel TREK-1 has been shown to be a potent target for depression treatment. Indeed, deletion of this channel in mice resulted in a depression resistant phenotype. The association of TREK-1 with the sorting protein sortilin
Externí odkaz:
https://doaj.org/article/52ef831cf78c4d7d9d4c693193d737af
Autor:
Alaeddine Djillani, Mariel Pietri, Sébastien Moreno, Catherine Heurteaux, Jean Mazella, Marc Borsotto
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Depression is a devastating mental disorder that affects 20% of the population worldwide. Despite their proven efficacy, antidepressants present a delayed onset of action and serious adverse effects. Seven years ago, we described spadin (PE 12-28) as
Externí odkaz:
https://doaj.org/article/82afa037b625468fb2e7f56da6976764
Autor:
Céline Hivelin, Sophie Béraud-Dufour, Christelle Devader, Amar Abderrahmani, Sébastien Moreno, Hamid Moha ou Maati, Alaeddine Djillani, Catherine Heurteaux, Marc Borsotto, Jean Mazella, Thierry Coppola
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Inhibition of the potassium channels TREK-1 by spadin (SPA) is currently thought to be a promising therapeutic target for the treatment of depression. Since these channels are expressed in pancreatic β-cells, we investigated their role in the contro
Externí odkaz:
https://doaj.org/article/5ce0b490bc014551ba4a958c50acb044
Autor:
Giuseppe Aceto, Argel Aguilar-Valles, Mir Hilal Ahmad, Aisha Asad Ahmed, Amani Ahmed, Muneer Ali, Muaweah Ahmad Alsaleh, Daniel Amen, Pedro Araos, João Ronielly Campêlo Araújo, Emily Arsenault, Dimitrinka Atanasova, Xabier Bengoetxea, Nelson Bennett, Alexandra H. Bettis, Cordian Beyer, Katarzyna Bialek, Jerzy Bodurka, Marc Borsotto, Patricia S. Brocardo, Patricia A. Broderick, Tarsis F. Brust, Steven L. Cofresi, Ryan Cook, Piotr Czarny, Marcello D’Ascenzo, Ayeila Daneshmend, Brian Dean, Jessica Di Re, Kurosh Djafarian, David J.A. Dozois, Kristen K. Ellard, Jean Daniel Eloy, Jay Faber, Mahino Fatima, María Flores-López, Anita Forsblom, Christopher J. Funes, Fred H. Gage, Piotr Gałecki, Keming Gao, Nuria García-Marchena, Arianna M. Gard, Gianna Giacoletti, Jennifer C.P. Gillies, Joana Gil-Mohapel, Xenia Gonda, Thomas A Green, Sandeep Grover, Girdhari Lal Gupta, Jessica L. Hamilton, Kelly J. Heard, Catherine Heurteaux, Stefanie Hoffmann, Azar Hosseini, Hossein Hosseinzadeh, Li-Ting Huang, Katriina Hyvönen, Marcus Ising, Sima Jafarirad, Zeynep Jihad-Mohamad, Manuel Jiménez-Navarro, Gábor Juhász, Michał Seweryn Karbownik, Mona Karimpour, Asma Kazemi, Katalin Adrienna Kékesi, Szabolcs Kéri, Daniel N. Klein, Edward Kowalczyk, Mateusz Kowalczyk, Jean-Claude Lacaille, Fernanda Laezza, Anna Landsman, Nikolai Lazarov, Richard T. Liu, Daniel M. Mackin, Paula M. Mangiavacchi, Edna Matta-Camacho, Jean Mazella, Soraya Mehrabi, Mariana S. Mendonça, Fermin Milagro, Akanksha Mishra, Dániel Mittli, Amal Chandra Mondal, Abdulwhab Shremo Msdi, Joona Muotka, Arezo Nahavandi, Brady D. Nelson, Melissa Nyveld, Ana Cristina de Oliveira Monteiro-Moreira, Vinood B. Patel, Cristine de Paula Nascimento-Castro, Francisco Javier Pavón, Peter Petschner, Efruz Pirdoğan Aydın, Evelini Plácido, Oscar Porras-Perales, Maria J. Portella, Victor R. Preedy, Rebecca B. Price, Päivi Pylvänäinen (Maria), Mahboobeh Ghasemzadeh Rahbardar, Mehran Rahimlou, Rajkumar Rajendram, Maria J. Ramirez, Bibi Marjan Razavi, Manivel Rengasamy, Nerea Requena-Ocaña, Álvaro F.L. Rios, M. Moshahid Alam Rizvi, Fernando Rodríguez de Fonseca, Swapnajeet Sahoo, Mirian Sanblas, Maria Semkovska, Antonia Serrano, Priyank Shah, Shubha Shukla, Monika Sienkiewicz, Sonu Singh, Tomasz Śliwiński, Minal Sonawane, Nahum Sonenberg, Rishi Sood, Kelly L. Sullivan, Fatimeh-Frouh Taghavi-Abkuh, Monika Talarowska, Jana Dimitrova Tchekalarova, Vanda Tukacs, Ece Türkyılmaz Uyar, Sofia Uribe, Krishna C. Vadodaria, Muriel Vicent-Gil, Erin B. Ware, Priscilla Gomes Welter, Paulina Wigner, Jesse Lee Wilde, Chunfu Wu, Jingyu Yang, Jiang-Hong Ye, Jian Zhang, Kuo Zhang, Molly Zhang, Sylwia Ziolkowska, Vadim Zotev, Qi Kang Zuo, Wanhong Zuo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8944ed76c5014a6aed75b7810dbeee
https://doi.org/10.1016/b978-0-12-817935-2.09990-6
https://doi.org/10.1016/b978-0-12-817935-2.09990-6
Sortilin, also called neurotensin (NTS) receptor-3 (NTSR3), displays a role of a multifunctional protein that is the consequence of its particular posttranslational and cellular properties. Sortilin is synthesized under a precursor form that is cleav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c49397093270848ea3c6fc1aa3cd869
https://doi.org/10.1016/b978-0-12-817935-2.00027-1
https://doi.org/10.1016/b978-0-12-817935-2.00027-1
Autor:
Hamid Moha Ou Maati, Catherine Widmann, Djamila Sedjelmaci, Bernard Gallois, Catherine Heurteaux, Marc Borsotto, Michel Hugues
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66194 (2013)
Stroke is one of a major cause of death and adult disability. Despite intense researches, treatment for stroke remains reduced to fibrinolysis, a technique useful for less than 10% of patients. Finding molecules able to treat or at least to decrease
Externí odkaz:
https://doaj.org/article/cb11dc94c9884aa9bd9f780fee077e0f