Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marangelie Criado-Marrero"'
Autor:
Marangelie Criado-Marrero, Sakthivel Ravi, Ekta Bhaskar, Daylin Barroso, Michael A. Pizzi, Lakiesha Williams, Cheryl L. Wellington, Marcelo Febo, Jose Francisco Abisambra
Publikováno v:
NeuroImage, Vol 298, Iss , Pp 120764- (2024)
Traumatic brain injuries (TBI) present a major public health challenge, demanding an in-depth understanding of age-specific symptoms and risk factors. Aging not only significantly influences brain function and plasticity but also elevates the risk of
Externí odkaz:
https://doaj.org/article/a65f8608a5d5467cb97194cbac21e60d
Autor:
Nashaly Irizarry-Méndez, Marangelie Criado-Marrero, Anixa Hernandez, Maria Colón, James T. Porter
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7097 (2024)
Fear conditioning evokes a physiologic release of glucocorticoids that assists learning. As a cochaperone in the glucocorticoid receptor complex, FKBP51 modulates stress-induced glucocorticoid signaling and may influence conditioned fear responses. T
Externí odkaz:
https://doaj.org/article/606a014e288a455ca2bbbcb08bbcc0fc
Autor:
Marangelie Criado-Marrero, Danielle M. Blazier, Lauren A. Gould, Niat T. Gebru, Santiago Rodriguez Ospina, Debra S. Armendariz, April L. Darling, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Tau accumulation and progressive loss of neurons are associated with Alzheimer’s disease (AD). Aggregation of tau has been associated with endoplasmic reticulum (ER) stress and the activation of the unfolded protein response (UPR). While E
Externí odkaz:
https://doaj.org/article/64dff707852e4d75bac6a3dfb818855a
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Lauren A. Gould, Danielle M. Blazier, Yamile Vidal-Aguiar, Taylor M. Smith, Salma S. Abdelmaboud, Lindsey B. Shelton, Xinming Wang, Jan Dahrendorff, David Beaulieu-Abdelahad, Chad A. Dickey, Laura J. Blair
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Abnormal accumulation of hyperphosphorylated tau induces pathogenesis in neurodegenerative diseases, like Alzheimer’s disease. Molecular chaperones with peptidyl-prolyl cis/trans isomerase (PPIase) activity are known to regulate these proc
Externí odkaz:
https://doaj.org/article/b06d2c045077424ca482d80168b5726e
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract The microtubule associated protein tau is an intrinsically disordered phosphoprotein that accumulates under pathological conditions leading to formation of neurofibrillary tangles, a hallmark of Alzheimer’s disease (AD). The mechanisms tha
Externí odkaz:
https://doaj.org/article/96db6774e5134960a85eb9d69ac1073a
Autor:
Marangelie Criado-Marrero, Taylor M. Smith, Lauren A. Gould, Sojeong Kim, Hannah J. Penny, Zheying Sun, Danielle Gulick, Chad A. Dickey, Laura J. Blair
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 9, Iss , Pp 100143- (2020)
Early life stress (ELS) adversely affects the brain and is commonly associated with the etiology of mental health disorders, like depression. In addition to the mood-related symptoms, patients with depression show dysregulation of the hypothalamic-pi
Externí odkaz:
https://doaj.org/article/1d59be1b34fb45a384cea2bd683efb31
Autor:
Santiago Rodriguez Ospina, Danielle M. Blazier, Marangelie Criado-Marrero, Lauren A. Gould, Niat T. Gebru, David Beaulieu-Abdelahad, Xinming Wang, Elizabeth Remily-Wood, Dale Chaput, Stanley Stevens, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 851 (2022)
The microtubule-associated protein tau pathologically accumulates and aggregates in Alzheimer’s disease (AD) and other tauopathies, leading to cognitive dysfunction and neuronal loss. Molecular chaperones, like small heat-shock proteins (sHsps), ca
Externí odkaz:
https://doaj.org/article/2ece1a9b1c4a46c8bd5a5ee4da623119
Correction to: Hsp90 co‑chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild‑type mice
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad, Laura J. Blair
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/46ce15823dae4f4db34d871dcda27a46
Autor:
Marangelie Criado-Marrero, Jonathan J. Sabbagh, Margaret R. Jones, Dale Chaput, Chad A. Dickey, Laura J. Blair
Publikováno v:
Cells, Vol 9, Iss 1, p 210 (2020)
Tau dysfunction is common in several neurodegenerative diseases including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Affective symptoms have often been associated with aberrant tau pathology and are commonly comorbid in patients wi
Externí odkaz:
https://doaj.org/article/9ded33bbd84a403cae4e1064f9df8b41
Autor:
Marangelie Criado-Marrero, Niat T. Gebru, Lauren A. Gould, Taylor M. Smith, Sojeong Kim, Roy J. Blackburn, Chad A. Dickey, Laura J. Blair
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2738 (2019)
Clinical studies show a significant association of childhood adversities and FK506-binding protein 5 (FKBP5) polymorphisms on increasing the susceptibility for neuropsychiatric disorders. However, the mechanisms by which early life stress (ELS) influ
Externí odkaz:
https://doaj.org/article/0e5905a28ea6441e81965f7a6648f097