Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Maram H, Zahra"'
Autor:
Hideki Minematsu, Said M. Afify, Yuki Sugihara, Ghmkin Hassan, Maram H. Zahra, Akimasa Seno, Masaki Adachi, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Previously, our group has demonstrated establishment of Cancer Stem Cell (CSC) models from stem cells in the presence of conditioned medium of cancer cell lines. In this study, we tried to identify the factors responsible for the induction o
Externí odkaz:
https://doaj.org/article/2dd3be2d767c48678d0e4eb56aa14b91
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cancer stem cells (CSCs) are suggested to be responsible for drug resistance and aggressive phenotypes of tumors. Mechanisms of CSC induction are still under investigation. Our lab has established a novel method to generate CSCs from iPSCs u
Externí odkaz:
https://doaj.org/article/f52d2c066b714211bfa9ad70628aea8a
Autor:
Ghmkin Hassan, Toshiaki Ohara, Said M. Afify, Kazuki Kumon, Maram H. Zahra, Xiaoying Fu, Mohamad Al Kadi, Akimasa Seno, David S. Salomon, Masaharu Seno
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cancer stem cells (CSCs) are generated under irregular microenvironment in vivo, of which mimic is quite difficult due to the lack of enough information of the factors responsible for cancer initiation. Here, we demonstrated that
Externí odkaz:
https://doaj.org/article/daf6adf4317e48ca892776e146be0047
Autor:
Kazuki Kumon, Said M. Afify, Ghmkin Hassan, Shunsuke Ueno, Sadia Monzur, Hend M. Nawara, Hagar A. Abu Quora, Mona Sheta, Yanning Xu, Xiaoying Fu, Maram H. Zahra, Akimasa Seno, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cancer stem cells (CSCs) are subpopulations in the malignant tumors that show self-renewal and multilineage differentiation into tumor microenvironment components that drive tumor growth and heterogeneity. In previous studies, our group succ
Externí odkaz:
https://doaj.org/article/94748b8e5a1d4c658dc75ade67ea7e3d
Autor:
Hager Mansour, Ph.D., Said M. Afify, Ph.D., Ghmkin Hassan, Ph.D., Hagar A. Abu Quora, Ph.D., Hend M. Nawara, Ph.D., Maram H. Zahra, Ph.D., Juan Du, Ph.D., Sadia Monzur, Ph.D., Toshiaki Ohara, M.D., Ph.D., Akimasa Seno, PhD, Masaharu Seno, Ph.D.
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 5, Iss , Pp 100062- (2022)
Metastasis is one of the major causes of cancer deaths. However, the mechanisms of cancer cells acquiring aggressiveness and metastatic potential are still under investigation. Although cancer stem cells (CSCs) have been suggested as tumor initiating
Externí odkaz:
https://doaj.org/article/ee1fe0fc410d44f9a94966074602ca1c
Autor:
Ghmkin Hassan, Said M. Afify, Maram H. Zahra, Hend M. Nawara, Kazuki Kumon, Yoshiaki Iwasaki, David S. Salomon, Akimasa Seno, Masaharu Seno
Publikováno v:
Cytotechnology. 75:243-253
Induced pluripotent stem cells (iPSCs) are useful tools for modeling diseases and developing personalized medicine. We have been developing cancer stem cells (CSCs) from iPSCs with conditioned medium (CM) of cancer-derived cells as the mimicry of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff36a9153d9a8c660271ca46a223204
https://doi.org/10.1007/s10616-023-00575-1
https://doi.org/10.1007/s10616-023-00575-1
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 500 (2021)
Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism that disrupts the dynamics of microtubules and induces mitotic arrest and
Externí odkaz:
https://doaj.org/article/904619f709ce416c99780c7a258f5689
Autor:
Said M, Afify, Ghmkin, Hassan, Hiroko, Ishii, Sadia, Monzur, Hend M, Nawara, Amira, Osman, Hagar A, Abu Quora, Mona, Sheta, Maram H, Zahra, Akimasa, Seno, Masaharu, Seno
Publikováno v:
Advances in experimental medicine and biology. 1393
Cancer stem cells (CSCs) are small subpopulation sharing similar properties like normal stem such as self-renewal and differentiation potential to direct tumor growth. Last few years, scientists considered CSCs as the cause of phenotypic heterogeneit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f72397fc4748de2b83ea16bd2e8e48c0
https://pubmed.ncbi.nlm.nih.gov/36587303
https://pubmed.ncbi.nlm.nih.gov/36587303
Publikováno v:
Advances in experimental medicine and biology. 1393
Many tumors are resistant to conventional cancer therapies because a tumor is composed of heterogeneous cell population. Especially, subpopulation of cancer stem cells, which have self-renewal and differentiation properties and responsible for the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4d3fa3660b0b5abdc1e3cf542bef6bb
https://pubmed.ncbi.nlm.nih.gov/36587305
https://pubmed.ncbi.nlm.nih.gov/36587305
Autor:
Sadia Monzur, Masaharu Seno, Hend M. Nawara, Akimasa Seno, Juan Du, Maram H. Zahra, Hagar A. Abu Quora, Ghmkin Hassan, Said M. Afify, Ryo Uesaki, Hager Mansour, Mona Sheta, Samah El-Ghlban
Publikováno v:
Biochemical and Biophysical Research Communications. 583:49-55
Cancer stem cells (CSCs) are responsible for cancer initiation, drug resistance, and aggressive tumor phenotypes. Our lab has established a novel method to induce CSCs from induced pluripotent stem (iPS) cells in a microenvironment mimicking chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f11aa20eaf3d33b4d1dbc5ef8e4269
https://doi.org/10.1016/j.bbrc.2021.10.047
https://doi.org/10.1016/j.bbrc.2021.10.047