Stereoselective synthesis of (R)-7-pentylhexahydroazepine-2-thione: Formal precursor of (−)-perhydrohistrionicotoxin

Autor: Duhamel, Pierre, Kotera, Mitsuharu, Marabout, Benoit

Publikováno v: In Tetrahedron: Asymmetry 1991 2(3):203-206

SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair.

Autor: Ferzaz B; Discovery Research, Central Nervous System Research Department, Sanofi-Synthélabo Recherche, 31 avenue P. Vaillant-Couturier, 92225 Bagneux Cedex, France. badia.ferzaz@sanofi-synthelabo.com, Brault E, Bourliaud G, Robert JP, Poughon G, Claustre Y, Marguet F, Liere P, Schumacher M, Nowicki JP, Fournier J, Marabout B, Sevrin M, George P, Soubrie P, Benavides J, Scatton B

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2002 Jun; Vol. 301 (3), pp. 1067-78.